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All Journal Journal SAGO Gizi dan Kesehatan Jurnal Kesehatan Farmasi
Haliza, Yosie
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Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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INOVASI KOSMETIK BAHAN ALAM DARI EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) SEBAGAI KRIM TABIR SURYA Aulianshah, Vonna; Haliza, Yosie; Juwita, Putri Rusma; Alviona, Sapta; Yamara, Putri; Pamudi, Berwi Fazri; Chairunnisa, Chairunnisa
Jurnal Kesehatan Farmasi Vol 6 No 2 (2024)
Publisher : Jurusan Farmasi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jkpharm.v6i2.2639

Abstract

Latar Belakang: Pemanfaatan herbal sebagai bahan aktif kosmetik dipercaya oleh sebagaian masyarakat lebih aman jika dibandingkan dengan senyawa kimia sintetik. Manggis (Garcinia mangostana L.) diketahui dari beberapa penelitian memiliki aktifitas antioksidan. Penelitian ini merupakan penelitian eksperimental yang bertujuan untuk memformulasikan ekstrak kulit manggis menjadi sediaan krim tabir surya sebagai inovasi perkembangan kosmetik bahan alam yang sesuai persyaratan SNI. Metode: Formulasi krim ekstrak kulit manggis dibuat dengan 3 variasi kosentrasi yaitu 1%; 3% dan 5%, sedangkan sebagai kontrol digunakan basis krim tanpa penambahan ekstrak. Selanjutnya dilakukan evaluasi organoleptik, pH, viskositas dan sun Protecting Factor (SPF) sesuai persayaratan SNI 16-4399-19965. Hasil: Berdasarkan hasil evaluasi diperoleh hasil bahwa semua formula memenuhi syarat homogenitas. Nilai pH sediaan berkisar antara 4,6 sampai 6,3. Nilai Viskositas menujukkan nilai antara 7.299 – 14.133 mPa.S. Pada uji penentuan nilai SPF hanya krim dengan konsentrasi 3% dan 5% yang memenuhi syarat nilai SPF (>4) masing-masing dengan nilai 8,3 dan 13,4. Kesimpulan: Maka dapat disimpulkan bahwa esktrak kulit manggis dengan konsentrasi 3% dan 5% dapat diformulasikan sebagai krim tabir surya sesuai dengan persyaratan SNI.
Studi komparatif kadar total flavonoid pada ekstrak n-heksana, etil asetat dan etanol daun mangkokan (Polyscias scutellaria) menggunakan spektrofotometer UV-Vis Safrina, Safrina; Haliza, Yosie
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 3B (2024): Nopember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i3B.1923

Abstract

Background: Mangkokan leaves (Polyscias scutellaria) are a plant with a million benefits from its extraordinary flavonoid content. Flavonoids are a group of compounds that are attracting attention because of their broad potential health benefits and applications in various fields, including nutrition, pharmaceuticals, and medicine.Objectives: Determine the total flavonoid content of mangkokan leaf extract using n-Hexane, ethyl acetate, and 70% ethanol as solvents.Methods: This is an experimental laboratory study by determining the total flavonoid content of mangkokan leaf extract (Polyscias scutellaria) based on differences in solvent polarity using UV-Vis spectrophotometry and comparing its flavonoid content with the ANOVA comparison test. The research was conducted at the Biology Biostatics Laboratory of the Faculty of Mathematics and Natural Sciences, Syiah Kuala University, the Biology Laboratory of the Aceh Ministry of Health Polytechnic, the Chemistry Laboratory of the Faculty of Mathematics and Natural Sciences, Syiah Kuala University, and the Pharmacy Laboratory of the Faculty of Mathematics and Natural Sciences, Syiah Kuala University, from December 1, 2023, to March 31, 2024. A sample of 1,5 kg of mangkokan leaves was obtained from Reuloh, Darul Imarah District, Aceh Besar Regency. The analysis carried out on the sample was phytochemical analysis and flavonoid content using a UV-Vis spectrophotometer instrument. The data obtained were analyzed statistically using the one-way ANOVA method.Results: The best results for determining the total flavonoid content of mangkokan leaves were given by the ethyl acetate extract solvent, namely 25,112 mgQE/g, followed by n-Hexane extract at 22,335 mgQE/g and 70% ethanol extract at 14,285 mgQE/g. The ANOVA test results showed that differences in solvents influenced the total flavonoid content of mangkokan leaf extract with a P value =0,00.Conclusion: The total flavonoid content of mangkokan leaf extract using an ethyl acetate solvent was higher compared to ethanol and n-Hexane solvents.KeywordsMangkokan leaves (Polyscias scutellaria), flavonoids, N-Hexane, ethyl acetate, Ethanol
Co-Authors Alviona, Sapta Aulianshah, Vonna Chairunnisa Chairunnisa Juwita, Putri Rusma Pamudi, Berwi Fazri Safrina Safrina, Safrina Yamara, Putri