Article Per Year (5 Year)
p-Index From 2020 - 2025
1.116
P-Index
This Author published in this journals
All Journal Journal SAGO Gizi dan Kesehatan International Journal of Health and Pharmaceutical (IJHP) Jurnal Kesehatan Farmasi Jurnal Ilmiah Farmasi Simplisia
Aulianshah, Vonna
Jurusan Farmasi Politeknik Kesehatan Kemenkes Aceh, Aceh, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 7 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 7 Documents
Search

 1 
Peningkatan pengetahuan dan keterampilan siswa-siswi dalam pemanfaatan daun sirsak (Annona Muricata L.) untuk pencegahan dan pengobatan berbagai penyakit Noni Zakiah; Munira Munira; Vonna Aulianshah; Rasidah Rasidah; Farida Hanum
Jurnal SAGO Gizi dan Kesehatan Vol 1, No 2 (2020): Januari - Juni
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v1i2.405

Abstract

Background: The use of traditional medicines is increasingly massive, it takes packaging and handling practical ways for the community. Soursop leaf is one of the herbs known to have many pharmacological properties for health. Capsules are an alternative form of packaging that is efficient for the community because in addition to ease of use, it can also mask the unpleasant taste and smell of simplicia.Objectives:  This aims to improve the skills of students in the use of soursop (Annona Muricata L.) leaves for the prevention and treatment of various diseases.Methods: This study was used a quasi-experimental design with a postest only approach. This activity was carried out by providing counseling (lecture method) and providing skills on how to package the soursop leaf simplicia powder into a capsule shell on 28 November 2018 at Suka Makmur High School, Aceh Besar. Direct data collection, and analysis using t-dependent tests.Results: The results of the study have shown an increase in the skills of students in the use of soursop (Annona muricata L.) leaves for the prevention and treatment of various diseases after counseling (p <0.05).Conclusion: Increasing the knowledge of students related to prevention and treatment can be done through counseling, namely counseling about the use of soursop leaves (Annona muricata L.)
Efek sitotoksik ekstrak buah kapulaga jawa (Amomum compactum Soland. Ex. Maton) Nailul Muna; Noni Zakiah; Vonna Aulianshah; Munira Munira; Amelia Sari
Jurnal SAGO Gizi dan Kesehatan Vol 1, No 1 (2019): Juli - Desember
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v1i1.302

Abstract

Background: In developed countries cancer is the second leading cause of death after cardiovascular disease. Cancer prevention can be done with synthetic or traditional medicine. However, synthetic treatments often cause side effects and of course require high costs. Java Cardamom (Amomum compactum Soland. Ex Maton) is a plant that contains antioxidants. Antioxidants can inhibit oxidation reactions by binding to free radicals and molecules that are very reactive so that cell damage can be prevented. Cardamom contains flavonoids which can induce cell death programs as well as tannins as free radical scavengers.Objectives: This study aims to determine the LC50 value of Java cardamom (Amomum compactum Soland. Ex Maton) on Artemia salina Leach.Methods: This study was an experimental study using a completely randomized design (CRD) using 180 artemia larvae which were divided into 6 treatment groups. Each group included 10 artemia larvae with varying concentrations of 500 ppm, 250 ppm, 100 ppm, 50 ppm, 10 ppm and 0 ppm (not given extract). Three repetitions were performed for each concentration.Results: The results showed from the observations obtained the LC50 value of Java cardamom extract is 26.60 ppm. So that the Java cardamom extract (Amomum compactum Soland. Ex Maton) has the potential as an anticancer (cytotoxic).Conclusion: Java cardamom extract (Amomum compactum Soland. Ex Maton) is active and can be developed as an anticancer compound.
Anti-Inflammatory Effect Of Carica Papaya Leaves Extract In Male Wistar Rats Based On Variation Of Concentration Aulianshah, Vonna; Ratu Thaharah, Yelda; Zakiah, Noni; Handayani, Rini
International Journal of Health and Pharmaceutical (IJHP) Vol. 4 No. 3 (2024): August 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v4i3.279

Abstract

Treatment of inflammation is currently dominated by using synthetic drugs, which if used in cases of chronic inflammation such as hyperuricemia and rheumatoid arthritis will carry the risk of increasing side effects for the user. Papaya leaves as a potential herb in some communities are also used as a treatment for inflammatory conditions. The aim of this research was to determine the anti-inflammatory effect of papaya leaf extract in vivo based on variations in concentration in Wistar white rats. This research is an in vivo study using 25 male Wistar Rats and divided into 5 groups. Group I was given as a negative control (P0), the group used Diclofenac Sodium as a positive control (P1), the Carica papaya leaf extract test group with varying concentrations of 40% (P2), 50% (P3), and 60% concentration (P4). Carrageenan 1% is used as an inflammation inducer. The inflammation observation parameter in this study was the volume of edema in the rats' feet at 30 minute intervals for 180 minutes. The average percentage reduction in edema during 180 minutes of observation in the P2, P3 and P4 extract test groups was 81.00%, 78.33% and 81.00%, respectively. The positive control group (P1) showed a reduction of 81.66%, while the negative control was only 26%. The results of statistical tests show that there is an effect of giving the extract on reducing edema in mice compared to the negative control group. From these results it can be concluded that the ethanol extract of Carica papaya leaves with concentrations of 40%, 50% and 60% showed an anti-inflammatory effect on male Wistar rats.
INOVASI KOSMETIK BAHAN ALAM DARI EKSTRAK KULIT MANGGIS (Garcinia mangostana L.) SEBAGAI KRIM TABIR SURYA Aulianshah, Vonna; Haliza, Yosie; Juwita, Putri Rusma; Alviona, Sapta; Yamara, Putri; Pamudi, Berwi Fazri; Chairunnisa, Chairunnisa
Jurnal Kesehatan Farmasi Vol 6 No 2 (2024)
Publisher : Jurusan Farmasi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jkpharm.v6i2.2639

Abstract

Latar Belakang: Pemanfaatan herbal sebagai bahan aktif kosmetik dipercaya oleh sebagaian masyarakat lebih aman jika dibandingkan dengan senyawa kimia sintetik. Manggis (Garcinia mangostana L.) diketahui dari beberapa penelitian memiliki aktifitas antioksidan. Penelitian ini merupakan penelitian eksperimental yang bertujuan untuk memformulasikan ekstrak kulit manggis menjadi sediaan krim tabir surya sebagai inovasi perkembangan kosmetik bahan alam yang sesuai persyaratan SNI. Metode: Formulasi krim ekstrak kulit manggis dibuat dengan 3 variasi kosentrasi yaitu 1%; 3% dan 5%, sedangkan sebagai kontrol digunakan basis krim tanpa penambahan ekstrak. Selanjutnya dilakukan evaluasi organoleptik, pH, viskositas dan sun Protecting Factor (SPF) sesuai persayaratan SNI 16-4399-19965. Hasil: Berdasarkan hasil evaluasi diperoleh hasil bahwa semua formula memenuhi syarat homogenitas. Nilai pH sediaan berkisar antara 4,6 sampai 6,3. Nilai Viskositas menujukkan nilai antara 7.299 – 14.133 mPa.S. Pada uji penentuan nilai SPF hanya krim dengan konsentrasi 3% dan 5% yang memenuhi syarat nilai SPF (>4) masing-masing dengan nilai 8,3 dan 13,4. Kesimpulan: Maka dapat disimpulkan bahwa esktrak kulit manggis dengan konsentrasi 3% dan 5% dapat diformulasikan sebagai krim tabir surya sesuai dengan persyaratan SNI.
EFEKTIVITAS KOMPRES PANAS DAN DINGIN TERHADAP NYERI DISMENORE Aulianshah, Vonna; Nafisa, Azwa; Rizka, Ramaza; Silviana, Ernita; Pamudi, Berwi Fazri
Jurnal Kesehatan Farmasi Vol 7 No 1 (2025): Jurnal Kesehatan Farmasi
Publisher : Jurusan Farmasi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jkpharm.v7i1.2829

Abstract

Metode: Penelitian eksperimental ini melibatkan 20 responden yang dibagi ke dalam dua kelompok intervensi. Tingkat nyeri diukur menggunakan Numerical Rating Scale (NRS) sebelum dan sesudah pemberian kompres panas (40–45°C) atau kompres dingin (15–18°C) selama 15 menit. Data dianalisis menggunakan uji Paired T-test dan Independent T-test. Hasil: Baik kompres panas maupun dingin secara signifikan menurunkan tingkat nyeri (p < 0,05). Namun, penurunan rata-rata skala nyeri lebih besar pada kelompok kompres panas (4,40) dibandingkan dengan kompres dingin (1,20). Hasil uji Independent T-test menunjukkan perbedaan signifikan antara kedua intervensi (p = 0,001), dengan kompres panas lebih efektif. Kesimpulan: Kompres panas dan dingin sama-sama efektif dalam mengurangi nyeri dismenore, namun kompres panas terbukti lebih efektif berkat efek vasodilatasinya yang meningkatkan sirkulasi darah dan mengurangi ketegangan otot.
PENGARUH WAKTU PEMETIKAN TERHADAP KADAR FLAVONOID TOTAL DAN AKTIVITAS ANTIOKSIDAN ESKTRAK DAUN KELOR (Moringa oleifera) Aulianshah, vonna; Rasidah, Rasidah; Handayani, Rini
JURNAL ILMIAH FARMASI SIMPLISIA Vol. 4 No. 2 (2024): Desember 2024
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jifs.v4i2.708

Abstract

Moringa is a plant that is believed to have antioxidant activity that is able to provide cell defense against reactive oxygen species that cause cell damage. This activity is likely mediated by the high total flavonoid content of Moringa leaves, but the chemical content of the plant is highly dependent on several factors, one of which is the time of picking or picking. The purpose of this study is to determine the effect of picking time on the total level of flavonoids and antioxidant activity of Moringa leaf extract (Moringa oleifera). The study was experimental by using two bound variables, namely total flavonoid levels and antioxidant activity from moringa leaf extract collected with different picking, namely at 6-7 a.m (EEDK1), 12-13 p.m (EEDK2) and 17-18 p.m (EEDK3) on the same day. Moringa leaf extract is made using a repetitive maceration method with a 70% ethanol solvent. The measurement of total flavonoid levels was carried out by spectrophotometry method with a concentration of 10,000 ppm and used quercetin as the benchmark standard. Antioxidant activity was determined through the DPPH method with extract concentrations of 20, 40, 60, 80 and 100 ppm. The measurement results were analyzed for the percentage of inhibition and the IC50 (inhibitory concentration) value was calculated using the linear regression curve equation. Vitamin C was used as a comparison The measurement results of each test sample showed a significant difference in the percentage of inhibition and IC50 value, where EEDK1 was the most active and categorized as very strong with a value of 45.08 ppm. With these significant differences, it can be concluded that the picking time affects the total flavonoid levels and anti-oxidation activity of Moringa leaves
UJI EFEKTIVITAS EKSTRAK BIJI PEPAYA (Carica papaya L.) SEBAGAI ANTHELMINTIK TERHADAP CACING Ascaridia galli: UJI EFEKTIVITAS EKSTRAK BIJI PEPAYA (Carica papaya L.) SEBAGAI ANTHELMINTIK TERHADAP CACING Ascaridia galli Khaliza, Nur; Handayani, Rini; Aulianshah, Vonna; Zakiah, Noni; Munira, Munira; Nindia, Yuni
JURNAL ILMIAH FARMASI SIMPLISIA Vol. 5 No. 1 (2025): Juni 2025
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/jifs.v5i1.890

Abstract

Infeksi cacing masih menjadi masalah kesehatan yang umum di negara tropis seperti Indonesia. Salah satu tanaman yang banyak dibudidayakan di Indonesia adalah pepaya (Carica papaya L.), yang bijinya diketahui memiliki sifat anthelmintik, tetapi biji pepaya seringkali dibuang tanpa dimanfaatkan. Penelitian ini bertujuan untuk mengetahui efek ekstrak biji pepaya terhadap mortalitas cacing Ascaridia galli. Sebanyak 75 ekor cacing digunakan dalam penelitian ini, dibagi dalam tiga kali ulangan, masing-masing terdiri dari lima kelompok perlakuan: kontrol negatif (NaCl 0,9%), kontrol positif (Pirantel Pamoat 0,5%), serta ekstrak biji pepaya dengan konsentrasi 10%, 15%, dan 20%. Penilaian dilakukan berdasarkan skor gerakan cacing setelah inkubasi selama 12, 24, dan 36 jam. Skor 2 diberikan jika seluruh tubuh cacing bergerak, skor 1 diberikan jika cacing tidak bergerak namun masih hidup, dan skor 0 diberikan jika cacing mati. Hasil uji in vitro menunjukkan bahwa ekstrak biji pepaya 10% menyebabkan kelumpuhan pasca inkubasi 12 jam pertama dan kematian seluruh cacing setelah 24 jam pasca inkubasi. Konsentrasi 15% dan 20% menyebabkan kematian pada semua cacing pasca inkubasi 12 jam pertama. Hasil penelitian ini dapat disimpulkan bahwa ekstrak biji pepaya konsetrasi 10%, 15% dan 20% efektif sebagai anthelmintik terhadap Ascaridia galli.
Co-Authors Alviona, Sapta Amelia Sari Chairunnisa Chairunnisa Farida Hanum Haliza, Yosie Juwita, Putri Rusma Khaliza, Nur Munira Munira Munira Munira Munira Munira, Munira Nafisa, Azwa Nailul Muna Nindia, Yuni Noni Zakiah Noni Zakiah Noni Zakiah Pamudi, Berwi Fazri Rasidah Rasidah Rasidah Rasidah, Rasidah Ratu Thaharah, Yelda Rini Handayani Rizka, Ramaza Silviana, Ernita Yamara, Putri