Article Per Year (5 Year)
p-Index From 2021 - 2026
1.244
P-Index
This Author published in this journals
All Journal International Journal of Applied and Scientific Research (IJASR) International Journal of Global Sustainable Research International Journal Of Public Health International Journal Of Health And Social Behavior
Ohiwerei Wisdom Omogbai
Unknown Affiliation
Religion Humanities Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Nursing Public Health Social Sciences

Published : 8 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 8 Documents
Search

 1 
Gender-Based Comparative Study Of The Influence Of Cola Nitida On Urine Calcium And Magnesium Concentrations Of Humans Igbinovia Igbinovia; Edokpolor Nestor; Ohiwerei Wisdom Omogbai; Festus, Oloruntoba O.; Ibhadode Adesua; Echekwube Marylyn E
International Journal of Health and Social Behavior Vol. 1 No. 4 (2024): November : International Journal of Health and Social Behavior
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijhsb.v1i4.181

Abstract

How Cola nitida could affect the urine calcium and magnesium concentrations of the male human subjects in comparison to the female counterpart were focused on. Sixty subjects (males=30 and females=30) and unaccustomed to Cola nut eating were involved. Their age range was between 18 and 28years. Three (3) sub-categories were involved: underweight=10, normal weight=10 and overweight=10. Hypertensive, renal and any subject with cardio-pulmonary-related conditions were exempted from the study. The normal chamber temperature, (RT=270C and RH=70%), the raised chamber temperature (RT =370C and RH=90%) were studied. Sequel to the foregoing, the subjects sat quietly in the sweat chamber for 20 minutes. The third experimental condition was the normal chamber temperature with exercise (RT=270C and RH=70%) and the subjects rode a bicycle ergometer at 750J/minute for 20 minutes. All of these happened prior to the consumption Cola nitida. Ahead of the experimentation in the sweat chamber, the subject urinated in a container in order for the timed urine volume to be measured and urine was again taken at the end of the experimentation that was also measured in order to obtain the actual urine volume within the given period. Thereafter, the urinary flow rate was calculated. The urine calcium and magnesium concentrations were likewise estimated. 0.5g/kg body weight of Cola nitida was given to each subject and chewed as a bolus. After swallowing, 50ml of deionized water was given to each subject to drink and the subject was allowed to rest for 90 minutes before being brought into the sweat chamber. The results showed that in respect to urine Ca ions concentration, no significant change was observed in a comparison between the males and females after the ingestion of Cola nitida under normal, raised temperature and exercise experimental conditions. As regards urine Mg ions concentration, no significant change was observed in a comparison between the males and females after the ingestion of Cola nitida under normal and exercise experimental conditions. However, there was a significant increase in Mg ions concentration in the female UW and NW subjects compared to the males after the consumption of Cola nitida under raised temperature condition.
Gender-Based Comparative Study Of The Influence Of Cola Nitida On The Sweat Sodium, Potassium And Chloride Concentrations Of Humans Igbinovia Igbinovia; Edokpolor Nestor; Ohiwerei Wisdom Omogbai; Ibhadode Adesua; Festus, Oloruntoba O.; Echekwube Marylyn E
International Journal of Public Health Vol. 1 No. 4 (2024): December : International Journal of Public Health
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62951/ijph.v1i4.191

Abstract

The study investigated how Cola nitida affects the sweat concentrations of sodium (Na), potassium (K), and chloride (Cl) in male and female subjects. Sixty healthy participants (30 males, 30 females) aged 18–28 years, with varying body weights (underweight, normal weight, overweight), were selected. Subjects were exposed to three conditions: normal chamber temperature (27°C, 70% RH), raised temperature (37°C, 90% RH), and exercise at normal temperature (27°C, 70% RH) while riding a bicycle ergometer at 750J/min for 20 minutes. Prior to the experiment, 0.5g/kg body weight of Cola nitida was consumed, followed by a 90-minute rest. Sweat samples were collected to measure ion concentrations. Results showed no significant changes in sodium (Na) concentrations between males and females under normal and raised temperature conditions. However, under exercise conditions, there was a significant increase in sweat Na in female underweight subjects compared to males. Regarding chloride (Cl), there was no significant difference between males and females under all conditions. For potassium (K), significant increases were observed in the sweat of female underweight subjects compared to males in normal, raised temperature, and exercise conditions. Conversely, decreases in sweat potassium were noted in female normal weight subjects under normal conditions and overweight subjects under raised temperature and exercise conditions compared to males.
Histological Effect of Ultra Violet (UV) Light on the Brain of Albino Wistar Rats Uwuigbe Mathew; Ohiwerei Wisdom Omogbai; Edebiri Ogbemudia; Ajanwachukwu; Ogbonna Wilson
International Journal of Global Sustainable Research Vol. 2 No. 12 (2024): December 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59890/ijgsr.v2i12.2940

Abstract

UV light, or ultraviolet light, is a type of radiation that falls between the visible light and X-ray regions of the electromagnetic spectrum. It is a form of electromagnetic radiation emitted by the sun and artificial sources, such as tanning beds and UV lamps. It has a shorter wavelength than visible light, ranging from 100 to 400 nanometers (nm). It is categorized into three types based on their wavelengths: UVA, UVB, and UVC. The aim of this study is to evaluate the histopathological effect of uv light on the brain of adult Wistar albino rats. In all, fifty (50) adult Albino Wistar rats were used for this study. Group A served as the control and the rats were given distilled water. Animals in the test groups (B, C, D and E) were exposed to 30mins, 1hr, 2hrs and 4hrs of UV lights. After the administration, the rats were put under light chloroform anaesthesia and the brain harvested for histological processing. Short-term exposure (30 min daily) did not cause significant changes, whereas prolonged exposure (1 to 4 hours daily) led to pronounced gliosis, neuronal congestion, and axonal alterations. These findings suggest that chronic UV radiation exposure can have detrimental effects on neural integrity, possibly through oxidative stress, DNA damage, and vascular compromise. The long-term implications of these findings may extend beyond structural damage to include cognitive and behavioral deficits, underscoring the need for further investigations
Evaluation of the Effect of Ginger Zingiber Officinale Extract on Kidney of Albino Rat Administered with Graded Doses of Piroxicam Uwuigbe Mathew; Ohiwerei Wisdom Omogbai; Ajanwachukwu; Ogbonna Wilson; Edebiri Ogbemudia .E; Loveth Ada Adikwu
International Journal of Global Sustainable Research Vol. 3 No. 3 (2025): March 2025
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59890/ijgsr.v3i3.2997

Abstract

Ginger or ginger root is the rhizome of the plant Zingiber officinale, commonly consumed as a delicacy, medicine, or spice. It is named after its genus and belongs to the Zingiberaceae family. Ginger is native to southern China and later spread to the Spice Islands, other parts of Asia, West Africa, and the Caribbean. This study aims to evaluate the effects of ginger Zingiber officinale extracts on the kidney when administered alongside graded doses of piroxicam. Fifty albino rats were used, divided into five (5) equal groups (A to E) of ten (10) rats each. Group A served as the control, while Group B received 2.7mg/kg of piroxicam. Group C was administered 400mg/kg of ginger, Group D received 2.7mg/kg of piroxicam and 100mg/kg of ginger, and Group E received 2.7mg/kg of piroxicam along with 400mg/kg of gingerData on weight changes were analyzed using ANOVA, with statistical significance set at P < 0.05. All results were expressed as Mean ± Standard Error of Mean (SEM) and presented in tables for statistical comparison. However, Group B (administered 2.7mg/kg of piroxicam) displayed signs of renal distortion, while Group C (administered 400mg/kg of ginger) showed adipose tissue formation. Groups D and E, which received both piroxicam and ginger at different doses, exhibited normal histological features. Further research is recommended to determine the precise effects of mild, moderate, and high doses of Zingiber officinale (ginger) on kidneys affected by varying levels of piroxicam
Evaluation of the Histological Effects of Allium Cepa Administration on the Prostate Histology and Prostate Specific Antigen of Male Albino Rats Induced with Ciprofloxacin Mathew, Uwuigbe; Ohiwerei Wisdom Omogbai; Edebiri Ogbemudia E; Ajanwachukwu Ogbonna Wilson; Oriahoghen E E
International Journal of Applied and Scientific Research Vol. 2 No. 11 (2024): November 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The primary objective of this study is to assess the histological impact of Allium cepa administration on prostate histology and prostate-specific antigen (PSA) levels in male albino rats that were induced with ciprofloxacin. A total of 100 albino rats, each weighing between 150–250g, were used in the experiment. The experimental group was further divided into four subgroups, each containing 10 rats, labeled as Groups A, B, C, D, and E. Group A served as the control, while Group B received only ciprofloxacin. Group C was administered ciprofloxacin along with 100mg of Allium cepa extract, whereas Group D received ciprofloxacin and 200mg of Allium cepa extract. Group E was treated solely with Allium cepa extract. Groups B, C, and D were given 22.86 mg/kg of oral ciprofloxacin (500 mg/tablet), manufactured by Fidson Health Care Ltd. The ciprofloxacin was obtained from a reputable pharmaceutical store in Ekpoma, Edo State, and administered via gavage. The control group was provided with only water and food. The PSA levels in control and test subjects were recorded as Mean ± SEM. For the control group, the PSA level was 0.6250 ± 0.085 ng/ml. The PSA levels for test groups B, C, D, and E were 1.575 ± 0.417 ng/ml, 1.200 ± 0.123 ng/ml, 1.125 ± 0.048 ng/ml, and 3.300 ± 0.835 ng/ml, respectively. Notably, only Group E exhibited a significant increase (P<0.05) in PSA levels when compared to the control group.In conclusion, this study indicates that exposure to ciprofloxacin and Allium cepa at mild or moderate doses can lead to severe histopathological changes in the testis, prostate, and epididymis, with the exception of the brain
Histomorphological and Hormonal Changes in the Testes of Albino Rats Treated with Herbal Aphrodisiac Formular Wilson, Ajanwachukwu Ogbonna; Ohiwerei Wisdom Omogbai; Olugbenga Mary; Echekwube Marylyn E; Obeagu E I
International Journal of Applied and Scientific Research Vol. 2 No. 12 (2024): December 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Herbal supplements, commonly referred to as botanicals, are plant-derived products utilized for their therapeutic properties. This study aims to examine the histomorphological and hormonal changes in the testes of albino rats treated with a herbal aphrodisiac formula. A total of eight male and two female rats were used in the study, with the males divided into control and test groups, while the females were used for mating with the test groups. Group A (Control) received only normal feed (growers’ mash) and distilled water daily for four weeks. Group B was administered 0.2 ml of Men’s Formula supplement and sacrificed on day 7, whereas Group C was administered 0.2 ml of Men’s Formula supplement and sacrificed on day 14. The body weights of the animals were measured before and after acclimatization, and similar weight assessments were performed at the end of each phase, with the average weights recorded accordingly. At the end of the procedure, the testes of each rat were excised under chloroform anesthesia and fixed in 10% formal saline for subsequent histological examination. Blood samples were collected via cardiac puncture into plain bottles, and sera were later separated for hormonal analysis. The results indicated that the herbal aphrodisiac formula enhanced testosterone levels and increased testis weight. However, no significant change (P > 0.05) was observed in body weight, and testicular histology remained unaffected. Further studies with prolonged usage of the herbal aphrodisiac formula are recommended to determine potential long-term effects
Assessment of the Effect of Graded Doses Alligator Pepper on Uterus of Female Albino Rats Mathew, Uwuigbe; Ohiwerei Wisdom Omogbai; Amina Momodu; Ogbe O Clementina
International Journal of Applied and Scientific Research Vol. 2 No. 12 (2024): December 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The aim of this study is to determine the histological effects of alligator on the uterus of wistar rats, as a result of different doses of alligator administered orally. Fifty (50) adult female wistar rats were use for this study for a period of 28 days (14 days for aclimitization and 14 days for administration). The rats were randomized and divided into five groups (A, B, C, D and E) of ten (10) animals each. the animals were sacrificed two times. All animals were sacrificed by cervical dislocation at least three hours after the last administration of alligator pepper. The results showed the weight before acclimatization, after acclimatization, before sacrifice of control and test subjects in which the Mean±SEM of weight before acclimatization, after acclimatization, before sacrifice were 247±3.00, 226±2.00 and 226±2.00 respectively for control subjects. None of the test groups were found statistically significant (p<0.05) when compared with their respective control. The micrograph result showed that ovary group A in the photomicrograph had a normal histological features. Uterus group B administered with 100mg/kg of aqueous extracts of alligator pepper showed clear carcinoma (neoplastic changes) of the endomentry uterus. Uterus group C (200mg of Alligator pepper) and group D (300mg of Alligator pepper) showed hyperplasic cells of the endomentry uterus. Uterus group E (400g of Alligator pepper) photomicrograph showed andenomyosis endoutrolysis internal. In conclusion, hyperplasic cells ( a condition suggestive of Hyperplasia) was found to be more common in groups with moderate doses. This study suggests that the oral administration of Alligator pepper at mild or moderate doses could cause severe histopathologic changes in the uterus without having any adverse effect on body weight
Histological Effect of Ultra Violet (UV) Light on the Testis of Albino Wistar Rats Uwuigbe Mathew; Ohiwerei Wisdom Omogbai; Ogbe O Clementina; Ajanwachukwu Ogbonna Wilson; Obeagu E I
International Journal of Applied and Scientific Research Vol. 2 No. 12 (2024): December 2024
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

UV light, or ultraviolet light, is a type of radiation that falls between the visible light and X-ray regions of the electromagnetic spectrum. It is a form of electromagnetic radiation emitted by the sun and artificial sources, such as tanning beds and UV lamps. It has a shorter wavelength than visible light, ranging from 100 to 400 nanometers (nm). It is categorized into three types based on their wavelengths: UVA, UVB, and UVC. The aim of this study is to evaluate the histopathological effect of uv light on the testis of male Wistar albino rats. A total of fifty (50) adult Albino Wistar rats of comparable sizes were used for this study. They were divided into four equal groups (A – E) with ten (10) rats each. Group A served as the control and the rats were given distilled water and feed only. In addition to feed and water, Groups B rats were kept under Uv light for 30mins, Group C rats were kept under Uv light for 1hour twice daily, Group D rats were kept under Uv light for 2 hours thrice daily and Group E were kept under Uv light for 4 hours thrice daily. The administration was given daily for 14 days (2 weeks) and the weights of both the test and control animals was monitored before and after administration of Uv light. After the administration, the rats were put under light chloroform anaesthesia and the stomach was obtained. ANOVA was used to analyze the results of the weight and differences was considered significant at p<0.05 level of confidence. All data was expressed in table as mean ± standard deviation (SD). From the results, it was observed that Group B showed mild adenofibroma, Group C exhibited denatured testicular cells, indicating severe damage. Group D had adenocarcinoma and fatty tissue, suggesting potential malignancy and Group E presented fatty tissue. In conclusion, the exposure of testis to uv light cause significant alterations in testis histology
Co-Authors Ajanwachukwu Ajanwachukwu Ogbonna Wilson Amina Momodu Echekwube Marylyn E Edebiri Ogbemudia Edebiri Ogbemudia .E Edebiri Ogbemudia E Edokpolor Nestor Festus, Oloruntoba O. Ibhadode Adesua Igbinovia Igbinovia Loveth Ada Adikwu Mathew, Uwuigbe Obeagu E I Ogbe O Clementina Ogbonna Wilson Olugbenga Mary Oriahoghen E E Uwuigbe Mathew Wilson, Ajanwachukwu Ogbonna