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All Journal Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran
Muhammad Natsir Ilvira
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Evaluasi Pola Penggunaan Obat Tradisional dan Swamedikasi di Desa Bireuen Meunasah Blang Muhammad Natsir Ilvira; Fahmi Irsan Nasution; Hanafis Sastra Winata; Bayu Irvia Satria; Ekawaty Suryani Mastari
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v2i4.501

Abstract

The use of traditional medicine has long been integral to Indonesian society, offering affordable and accessible healthcare options. This study evaluates the patterns of traditional medicine use in Bireuen Meunasah Blang Village, focusing on respondent demographics, self-medication practices, and perceptions of affordability, effectiveness, and accessibility. Using a descriptive quantitative design, data were collected from 97 respondents aged 18–60 years through structured questionnaires. Results indicate that 54.6% of respondents demonstrate adequate use of traditional medicine, while 76.3% follow appropriate usage guidelines. Perceptions of cost and availability were predominantly positive, with 48.5% finding traditional medicines affordable and 70.1% familiar with their names. However, knowledge of side effects and sources of information remains limited. These findings underline the need for targeted public health education to enhance safe and informed self-medication practices with traditional medicines.
High Grade Myxoid Round Cell Liposarcoma Fahmi Irsan Nasution; Lely Hartati; Muhammad Natsir Ilvira
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 2 (2025): Agustus : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i2.6230

Abstract

Background: Myxoid liposarcoma is a malignant tumor composed of uniform, partially round to oval cells with lipoblast, in the myxoid stroma with branching capillaries. Very rarely presents as a primary neoplasm of the subcutis or retroperitoneum. Myxoid liposarcoma in the retroperitoneum is the most common metastases. Case description: We reported a case of Mr M, male, 48 years old, came to the hospital. Private in the city of Medan on April 19 2021 with complaints of upper left abdominal pain, nausea (+), vomiting (-), fever. vital sign, general condition: compos mentis, temperature: 36 ℃, Pulse: 80 x/min. Breathing: 20x/min, Blood pressure: 120/80 mmHg. Previously, a gastric biopsy was performed on suspicion of gastric carcinoma and a histopathological examination was carried out with the results of a gastric adenoma. Subsequently, an exploratory laparotomy was performed with tumor debulking and the tissue was sent to the H. Adam Malik Hospital unit. On macroscopic examination, the tissue was split in a state of 16 cm x 12 cm x 7 cm, yellowish-gray in color, chewy consistency. The of cutting, a solid mass of white, yellow, and brown color appears, the consistency is chewy and brittle. With a tissue-weight of 800 grams then labeled O/1260/21. On microscopic examination of the tumor mass, it appears that the tumor mass is mostly arranged in solid sheets, consisting of round, relatively uniform cells, arranged back to back. Round and oval nuclei with increased N/C ratio, coarse chromatin, eosinophilic cytoplasm. Among them are lipoblast cells with spider web and small signet ring lipoblast. Atypical mitoses are relatively easy to find > 19 mitoses / 10 LPB. Proliferative and congested blood vessels, necrotic masses <50% are also seen. Immunohistochemical examination was carried out with S100 positive staining results on the nuclear membrane and cytoplasm of tumor cells with a proportion of more than 70% moderate to strong intensity. Conclusion: Based on macroscopic and microscopic examination this patient was diagnosed with High grade myxoid round cell liposarcoma grade III with ICD-O 8852/3.
Comparison Of Reduction In Blood Pressure Between Sublingual and Oral Captopril Agustiawan, Agustiawan; Tabari, Muhammad Fadhlan La; Ilvira, Muhammad Natsir; Mastari, Ekawaty Suryani; Hardiyanti, Dwi
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 4 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i4.1794

Abstract

Background: Hypertensive crisis poses a high risk for long-term cardiovascular complications, and management focuses on controlled blood pressure (BP) reduction rather than immediate normalization. Objective: To compare the effectiveness of sublingual and oral captopril in reducing BP among patients with hypertensive urgency. Methods: A literature review was conducted using English-language studies published after 2012 that evaluated BP reduction outcomes of sublingual versus oral captopril. Results: Three relevant studies met the inclusion criteria, comparing both administration routes in hypertensive urgency management. All studies demonstrated that sublingual and oral captopril were similarly effective in lowering systolic and diastolic BP within the first few hours after administration. Sublingual captopril consistently produced a faster onset of action, with BP reduction observed within 15–30 minutes, whereas oral administration required 30–60 minutes to achieve comparable effects. None of the studies reported significant differences in adverse effects between the two routes. These findings suggest that while overall efficacy is comparable, the sublingual route provides more rapid BP control, which may be crucial in acute care settings. Conclusion: Both sublingual and oral captopril are effective options for hypertensive urgency, with the sublingual form offering a faster therapeutic response suitable for rapid BP reduction in emergency situations.
Interaksi Antara Defisiensi Vitamin A dan Anemia Defisiensi Zat Besi pada Anak : Perspektif Biomolekuler dan Patofisiologis Andy Sulaiman Siregar; Arfiany Marina Nasution; Muhammad Natsir Ilvira
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 2 No. 4 (2025): Oktober : Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v2i4.2338

Abstract

Vitamin A Deficiency (VAD) and iron deficiency anemia (IDA) are global nutritional issues affecting children, particularly in developing countries. The interaction between these two conditions can lead to a more complex condition known as Vitamin A Deficiency Anemia (VADA). This study aims to review the molecular relationship between Vitamin A deficiency and iron metabolism leading to VADA, as well as its impact on children's health. The methodology used in this article is a literature review of various clinical studies, epidemiological research, and relevant molecular experiments. The results show that VADA is primarily a functional iron deficiency, where iron absorption is impaired despite overall body iron levels not being critically low. This mechanism involves the regulation of hepcidin, redistribution of iron, and its effects on erythropoiesis. Additionally, therapy with Vitamin A supplementation has been shown to increase erythropoietin and hemoglobin production in children with dual deficiencies. The implications of these findings highlight the need for more integrated therapeutic strategies that consider both Vitamin A and iron status simultaneously. Further research is needed to understand the molecular mechanisms more deeply involved in this interaction and to develop more effective therapies for children with VADA.
Co-Authors Agustiawan Andy Sulaiman Siregar Arfiany Marina Nasution Bayu Irvia Satria Ekawaty Suryani Mastari Fahmi Irsan Nasution Hardiyanti, Dwi Lely Hartati Tabari, Muhammad Fadhlan La Winata, Hanafis Sastra