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All Journal Muhammadiyah Medical Journal Sanus Medical Journal
Kurnia, Achdi
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Sanus Medical Journal

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Fahr Disease : A Case Repor Abdulmannan, Adamilzary Fikry; Prodjokusumo, Hafidz Muhammad; Rahman, Putri Windiana; Fitriana, Rizni; Kurnia, Achdi
Sanus Medical Journal Vol. 7 No. 1 (2025)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v7i1.7955

Abstract

In Indonesia, life expectancy has risen significantly. The rise in life expectancy is, of course, directly proportional to the rise in the elderly population (elderly). Coronary heart disease, hypertension, metabolic disorders, and arthritis are all problems that the elderly face on a daily basis. To improve the quality of life of the elderly, preventive efforts that are tailored to their physiological needs are required. However, descriptive data on the parameters to be examined in this group are required before conducting an intervention. The authors are encouraged to know the description of total cholesterol levels in the elderly who are in the DPC Muhammadiyah Pondok Aren environment based on the background of the problems described above. Glucose, hemoglobin, and total cholesterol levels in plasma will be measured. This study collects primary data from respondents by taking finger blood samples, which are then measured using the Easy Touch® tool. Total sampling was used, and the number of samples that met the inclusion criteria was 13 people. The data is analyzed to generate distributions and percentages. The findings revealed that 85.19 percent of the elderly had normal blood glucose levels. According to age, the elderly aged 60-74 years have 83.33 percent normal blood glucose levels, while the elderly aged 75-70 years have 86.67 percent normal blood glucose levels. According to gender, elderly men with normal blood glucose levels account for approximately 84.21 percent of the population, while elderly women with normal blood glucose levels account for approximately 87.50 percent. It was determined that over half of the elderly in PSTW
Synergistic Anti-inflammatory Activity of Tinospora crispa L. and Zingiber officinale: A BSA Assay Study Dewi, Sari Puspita; Kurnia, Achdi; Permata Sari, Shinta Dewi; Budiman, Muhamad Arif
Sanus Medical Journal Vol. 7 No. 1 (2025)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v7i1.20514

Abstract

Ginger rhizome (Zingiber officinale) and Tinospora crispa L. (Tinospora crispa L.) extracts contain various active compounds that have the potential to be anti-inflammatory agents. This study aims to evaluate the anti-inflammatory activity of ginger rhizome and Tinospora crispa L. leaf extracts, both singly and in combination, using the BSA test method. Extraction was carried out using the maceration method with 70% ethanol solvent. Anti-inflammatory activity tests were carried out in vitro at 75, 100, and 150 μg/mL concentrations by measuring the extract's ability to prevent heat-induced BSA denaturation. The yield of Tinospora crispa L. extract reached 41.39% and that of ginger extract 25.63%. The combination of 150 μg/mL extracts showed the highest anti- inflammatory activity (96.82%) of all the extract test samples. In comparison, the lowest anti-inflammatory activity was found in 75 μg/mL ginger extract, at 89.21%. Statistical tests showed a significant difference between the 75 μg/mL ginger extract and the 150 μg/mL combination (p=0.047). The combination of ginger and Tinospora crispa extract has the potential to be developed as a natural anti-inflammatory agent.
Co-Authors Abdulmannan, Adamilzary Fikry Budiman, Muhamad Arif Fitriana, Rizni Kirani, Elisa Safa Permata Sari, Shinta Dewi Prodjokusumo, Hafidz Muhammad Rahmadi, Agus Rahman, Putri Windiana Sari Puspita Dewi, Sari Puspita Sari, Shinta Dewi Permata