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All Journal Medical Journal of Indonesia CRJIM (Clinical and Research Journal in Internal Medicine)
Hasrianti, Nuvita
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Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Risk Factors Analysis of Diabetes Prevalence in Wetland Area: A Study from Borneo Wetland Study on Diabetes Fajari, Nanang Miftah; Hariyanto, Felix; Nur'amin, Hendra; Hasrianti, Nuvita
Clinical and Research Journal in Internal Medicine Vol. 5 No. 2 (2024): Volume 5 No 2, November 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.02.04

Abstract

Background: National Basic Health Survey held by the Ministry of Health Republic of Indonesia shows the prevalence of Diabetes Mellitus increased from 6.9% to 8.5% in 2018. Wetland is an area covered by shallow water on the surface, which represents a unique ecosystem. Aim: This study investigated the association between various risk factors and DM prevalence in South Kalimantan Wetlands, Indonesia. Early identification and management of risk factors may prevent progression into diabetes mellitus. Methods: We conducted the Borneo Wetland Study on Diabetes (Best-Diab 1) with a cross-sectional study approach using the latest health survey data conducted by the South Kalimantan Provincial Health Office from the primary health center visit from January 2020 to March 2022. Using Proportionate Random Sampling, we divided samples into two groups; 6.010 in the DM group, and 6.010 non DM group. Results: Gender, age, BMI, blood pressure, and blood glucose level were significantly correlated with diabetes mellitus prevalence (p<0.001). Family history of DM surprisingly has a significant impact on DM prevalence (PR, 3.16; 95% CI, 2.80-3.57, p<0.001). The prevalence of DM in the smoking group was 0.78 times less than in non-smoking individuals (PR, 0.78; 95% CI, 0.74-0.82; p<0.001). Excess sugar was the greatest risk factor for diabetes mellitus, with the prevalence of DM 4.72 times greater than normal sugar intake (PR, 4.72; 95% CI, 4.29-5.2; p<0.001). Excess salt intake also seemed to be a significant risk factor among DM patients (PR, 1.24; 95% CI, 1.17-1.30, p<0.001. Conclusion: Females, older age, higher BMI, and family history of DM were significant risk factors for diabetes mellitus prevalence in this study. Further studies are needed to determine how those factors impacted diabetes mellitus. Keywords: risk factors, prevalence, diabetes mellitus, wetland, South Kalimantan
Comparison of stingless bee honey and silver sulfadiazine on diabetic wound healing in rat models Fajari, Nanang Miftah; Pranoto, Agung; Perdanakusuma, David Sontani; Prenggono, Muhammad Darwin; Rudiansyah, Mohammad; Nur'amin, Hendra Wana; Syarifa, Yulia; Hasrianti, Nuvita; Saputri, Imelda Nita; Afrianto, Muhammad Irawan; Husna, Annisa Halida
Medical Journal of Indonesia Vol. 34 No. 3 (2025): September
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.257974

Abstract

BACKGROUND Diabetic foot ulcers (DFUs) are a major health concern in Indonesia. Adjuvant therapies may improve healing by avoiding secondary infections, promoting angiogenesis, and supporting oxygen circulation. This aimed to evaluate the effect of stingless bee honey (SBH) from Heterotrigona itama on diabetic wound size in rats (Rattus norvegicus), compared to silver sulfadiazine (SSD). METHODS An experimental study was conducted on 13 diabetic wounds in streptozotocin-induced diabetic rats treated with three types of therapies: SSD (n = 5), pure SBH (n = 5), and SBH with 20% water content (n = 3). The study initially involved 21 rats, but eight died during the diabetes modeling and wound observation phases, presumably due to hyperglycemia. Baseline characteristics did not differ significantly across the groups. RESULTS SBH with 20% water content and pure SBH reduced wound size by 95.1% and 92.1%, outperforming SSD (77.4%), with all therapies showing statistically significant improvement (p<0.05). However, the differences between groups were not statistically significant (p = 0.162). CONCLUSIONS Topically applied SBH is a potential natural therapeutic agent for diabetic wounds, in addition to standard treatment such as SSD.
Co-Authors Afrianto, Muhammad Irawan Agung Pranoto Annisa Halida Husna, Annisa Halida Hariyanto, Felix Mohammad Rudiansyah Nanang Miftah Fajari Nur'amin, Hendra Nur'amin, Hendra Wana Perdanakusuma, David Sontani Prenggono, Muhamad Darwin Saputri, Imelda Nita Syarifa, Yulia