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All Journal Sriwijaya Journal of Surgery Crown: Journal of Dentistry and Health Research
Reisha Notonegoro
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Dentistry Health Professions Medicine & Pharmacology Neuroscience Public Health

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Activated Growth Factors (AGF), an Advanced Platelet-Rich Plasma (PRP) Modality, as a Novel Biological Treatment for Partial Anterior Cruciate Ligament Tears: A Case Report Hidayat, Rachmat; Kemas Abdul Mutholib Luthfi; Olivia Azalia Putri; Sony Sanjaya; Linda Purnama; Sonya Syarifah; Nadia Khoirina; Abu Bakar; Rashidah Unaib Al Zayid; Reisha Notonegoro
Sriwijaya Journal of Surgery Vol. 8 No. 1 (2025): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v8i1.114

Abstract

Introduction: Partial anterior cruciate ligament (ACL) ruptures present a complex clinical challenge. Traditional treatment options, including conservative management and surgical reconstruction, often yield unpredictable outcomes and extended recovery periods. This case report explores the potential of activated growth factors (AGF), an advanced platelet-rich plasma (PRP) modality, as a novel biological treatment strategy for partial ACL tears. Case presentation: A 39-year-old male presented with right knee pain and instability following a twisting injury sustained during exercise. Magnetic resonance imaging (MRI) confirmed a partial tear of the anteromedial bundle of the ACL. The patient was treated with a series of three intra-articular injections of AGF, administered at weekly intervals. The AGF was prepared using a proprietary protocol aimed at optimizing growth factor concentration and release. The patient's progress was meticulously monitored through clinical evaluations and functional assessments at 3 and 6 months post-treatment. Conclusion: This case suggests that AGF may offer a promising alternative for the treatment of partial ACL tears, potentially facilitating accelerated healing and improved clinical outcomes. Further research, including controlled trials, is warranted to validate these findings and establish the efficacy and safety of AGF in a larger patient population.
The Impact of 3D Printing Technology on the Accuracy and Efficiency of Dental Implant Placement: A Randomized Controlled Trial in Semarang, Indonesia Reisha Notonegoro; Oliva Azalia Putri; Michelle Birne; Syaifudin Syaifudin; Indri Yani Septiana
Crown: Journal of Dentistry and Health Research Vol. 1 No. 1 (2023): Crown: Journal of Dentistry and Health Research
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/crown.v1i1.52

Abstract

Introduction: Accurate and efficient dental implant placement is crucial for successful treatment outcomes. Traditional implant placement techniques rely on 2D imaging and freehand surgery, which can be associated with inaccuracies and prolonged surgical time. This study aimed to evaluate the impact of 3D printing technology, specifically the use of patient-specific surgical guides, on the accuracy and efficiency of dental implant placement in Semarang, Indonesia. Methods: This randomized controlled trial included 60 patients requiring a single dental implant in the posterior mandible. Participants were randomly assigned to either the control group (conventional freehand implant placement) or the experimental group (3D printed surgical guide-assisted implant placement). Primary outcome measures were implant placement accuracy (deviation from planned implant position) and surgical time. Secondary outcomes included postoperative pain, swelling, and patient satisfaction. Results: The use of 3D printed surgical guides significantly improved implant placement accuracy in all three dimensions (mesiodistal, buccolingual, and apicocoronal) compared to the freehand technique (p<0.001). Surgical time was also significantly reduced in the experimental group (p=0.02). There were no significant differences between the groups in terms of postoperative pain, swelling, or patient satisfaction. Conclusion: 3D printing technology significantly enhances the accuracy and efficiency of dental implant placement. The use of patient-specific surgical guides resulted in more precise implant positioning and reduced surgical time, contributing to improved treatment outcomes.
Co-Authors Abu Bakar Indri Yani Septiana Kemas Abdul Mutholib Luthfi Linda Purnama Michelle Birne Nadia Khoirina Oliva Azalia Putri Olivia Azalia Putri RACHMAT HIDAYAT Rashidah Unaib Al Zayid Sony Sanjaya Sonya Syarifah Syaifudin