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All Journal Usadha Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Khuluq, Muh. Husnul
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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REAL WORLD DATA; EFFECTIVENESS OF COVID-19 TREATMENT IN SEVERE SYMPTOMS PATIENTS AT RS PKU MUHAMMADIYAH GAMPING IN AUGUST 2022-2023 Simamora, Patimah; Risdiana, Irma; Khuluq, Muh. Husnul; Perwitasari, Dyah A
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1133

Abstract

Severe COVID-19 has created significant real-world clinical challenges, particularly in the management of critically ill patients in intensive care units. The disease is often accompanied by serious complications, such as acute respiratory distress syndrome (ARDS), multiple organ damage, and increased risk of mortality, particularly in individuals with risk factors such as advanced age and comorbidities. Real World data provide evidence related to effectiveness as patients are observed from admission to discharge. This study aimed to obtain an overview of the effectiveness of COVID-19 treatment with severe symptoms at RS PKU Muhammadiyah Gamping in August 2022-2023. This observational study used a descriptive research design. Data collection was retrospective and was obtained from medical records. Descriptive analyses were conducted including patient characteristics, drug usage, and therapy effectiveness. This study obtained data from 45 patients who met the inclusion criteria for severe COVID-19 ...
KAJIAN PENGGUNAN OBAT KELASI BESI PADA PASIEN TALASEMIA MAYOR DI RSUD X KEBUMEN TAHUN 2023 Nurhasanah, Lutfia; Ainni, Ayu Nissa; Widiastuti, Tri Cahyani; Khuluq, Muh. Husnul
Usadha Journal of Pharmacy Vol. 4 No. 1 (2025): Februari
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v4i2.531

Abstract

Talasemia mayor merupakan jenis talasemia yang harus menjalankan transfusi darah seumur hidup. Obat kelasi besi digunakan untuk mengurangi peningkatan kadar besi dalam tubuh karena efek samping transfusi darah. Penggunaan obat kelasi besi, dapat menyebabkan efek yang signifikan, sehingga penting untuk mengkaji terapi pengobatan selama penggunaannya. Tujuan penelitian ini untuk mengetahui karakteristik pasien dan ketepatan penggunaan obat kelasi besi berdasarkan tepat indikasi, dosis, pasien, obat, dan rute pemberian obat di RSUD X Kebumen periode tahun 2023. Metode penelitian ini menggunakan metode  deskriptif, pengambilan data secara retrospektif. Populasi seluruh rekam medis pasien dengan diagnosis talasemia mayor periode Januari-Desember 2023 yang memenuhi kriteria inklusi yaitu pasien talasemia mayor yang sedang menjalani pengobatan kelasi besi. Berdasarkan hasil penelitian didapatkan sebanyak 74 pasien sesuai kriteria inklusi, jenis kelamin terbanyak perempuan (61%) dengan usia13-64 tahun (70,1%), obat kelasi besi yang paling banyak yaitu Deferipron 500 mg (68,9%). Ketepatan dosis Deferipron 500 mg (4%), Deferasirox 250mg (20%), Deferasirox 500 mg (67%), dan tepat rute pemberian (100%). Berdasarkan hasil penlitian etsrbut dapat disimpulkan bahwa kajian penggunaan obat kelasi besi pada pasien talasemia mayor di RSUD X masih terdapat beberapa pemberian obat yang tidak tepat dosis obat sebesar 59 pasien (79%).
Co-Authors Ainni, Ayu Nissa Irma Risdiana, Irma Nurhasanah, Lutfia Perwitasari, Dyah A Simamora, Patimah Widiastuti, Tri Cahyani