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All Journal JURNAL IBNU SINA BIOMEDIKA JURNAL ILMIAH MAKSITEK JURNAL ILMIAH SIMANTEK Jurnal Pandu Husada
Dian Erisyawanty Batubara
Universitas Muhammadiyah Sumatera Utara
Religion Agriculture, Biological Sciences & Forestry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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PERBANDINGAN EFEKTIFITAS EKSTRAK DAUN PEPAYA (Carica papaya) 100% DAN GENTAMISIN KRIM 0,1% TERHADAP KETEBALAN EPITEL PADA LUKA SAYAT TIKUS WISTAR (Rattus Norvegicus) Amanda, Alya; Batubara, Dian Erisyawanty
JURNAL IBNU SINA BIOMEDIKA Vol 1, No 1 (2017)
Publisher : UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (375.095 KB) | DOI: 10.30596/isb.v1i1.1108

Abstract

ABSTRAKLatar Belakang : Luka adalah rusak atau hilangnya jaringan tubuh. Selama ini penanganan standar pada luka adalah dengan pemberian antiseptik, antibiotik, dan anti radang. Salah satu tanaman yang bisa dijadikan tumbuhan obat adalah daun pepaya. Tanaman pepaya (Carica papaya) merupakan tanaman yang mudah tumbuh di dataran rendah maupun dataran tinggi, banyak dijumpai di Indonesia sebagai tanaman kaya manfaat. Para ilmuwan telah meneliti manfaat daun pepaya dalam bidang ilmu kedokteran modern, terutama dalam mempercepat penyembuhan luka karena mengandung enzim papain dan saponin. Tujuan : Membuktikan efektifitas pemberian ekstrak daun pepaya terhadap ketebalan epitel yang terbentuk pada luka sayat dibandingkan dengan gentamisin 0,1% pada tikus wistar selama proses penyembuhan luka. Metode : Penelitian ini merupakan penelitian eksperimen murni laboratorium untuk membandingkan efektifitas pemberian ekstrak daun pepaya terhadap ketebalan epitel yang terbentuk pada luka sayat dibandingkan dengan gentamisin 0,1% pada tikus wistar selama proses penyembuhan luka. Hasil : Rata-rata ketebalan epitel luka sayat yang terbentuk dengan pemberian ekstrak daun pepaya 100% adalah 355,18 µm sedangkan rata-rata ketebalan epitel luka sayat yang terbentuk dengan pemberian gentamisin 0,1% adalah 265,12 µm. Kesimpulan : Ekstrak daun pepaya 100% dapat dipertimbangkan sebagai salah satu alternatif untuk mempercepat pembentukan epitel luka sayat dari pada gentamisin 0,1%. Kata Kunci : Luka sayat, Ekstrak daun pepaya 100%, Gentamisin 0,1%, Ketebalan epitel.ABSTRACTBackground: Injuries are damaged or lost one of the body’s tissues all this time. Standard treatment of epidermal injury in medical ways were given antiseptic, antibiotic and anti-inflammatory. One of plant that can be medicinal plants is papaya leaf. Papaya plants (Carica papaya) is a plant that can growth easily in low land or high land, familiar in Indonesia as a plants with many beneficial. The scientist had research the benefits of papaya plants in medical science modern scope, especially in accelerating injuries healing process because it contains enzyme papain and saponin. Objective: To prove the effect of papaya leaf extract 100% againts epithelial thickness which formed by cut injury compared with gentamicin cream 0.1%  on wistar mice during healing injuries process. Methods: This research is an experimental laboratorium study to compare the effects of papaya leaf extract 100% against epithelial thickness which formed by cut injury compared with gentamicin cream 0.1%  on wistar mice during healing injuries process. Results: The mean of epithelial thickness with cut injuries was formed by given papaya leaf extract 100% is 355.18 (micrometer) the mean of epithelial thickness with cut injuries was formed by gentamicin cream 0.1% is 265.12 (micrometer). Conclusion: papaya leaf extract 100% can be considered as one of an alternative to accelerate the healing injuries process of cut injuries rather than gentamicin cream 0.1%.Keywords: cut injuries, papaya leaf extract 100%, gentamicin cream 0.1%, epithelial thickness.
UJI EFEKTIVITAS EKSTRAK KENCUR (Kaempferia galanga L.) TERHADAP PERTUMBUHAN CANDIDA ALBICANS SECARA IN VITRO Annisah, Rati; Batubara, Dian Erisyawanty; Roslina, Ance
JURNAL IBNU SINA BIOMEDIKA Vol 2, No 2 (2018)
Publisher : UNIVERSITAS MUHAMMADIYAH SUMATERA UTARA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (336.407 KB) | DOI: 10.30596/isb.v2i2.2598

Abstract

AbstrakLatar Belakang. Penyakit infeksi merupakan salah satu masalah kesehatan global baik di negara maju dan terlebih lagi di negara berkembang seperti Indonesia. Candida albicans merupakan suatu yeast patogen, secara normal ditemukan dalam tubuh manusia, spesies ini pada keadaan normal tidak berbahaya bagi tubuh.Namun, apabila terjadi gangguan seperti daya tahan tubuh yang lemah dan perubahan keseimbangan flora normal dapat menyebabkan penyakit kandidiasis. Kencur diketahui memiliki kandungan kimia seperti flavonoid, tannin, saponin dan minyak esensial yang bekerja sebagi anti fungal. Metode. Jenis penelitian yang dilakukan adalah penelitian eksperimental  post test only control group design disc difusiin method. Hasil. Hasil penelitian diperoleh bahwa ekstrak kencur memiliki daya hambat rata-rata terhadap pertumbuhan Candida albicans pada konsentrasi 40% dengan diameter resistansi 21,36 mm, konsentrasi 60% diameter hambatan 22,68 mm, konsentrasi diameter hambat 80% 24,74 mm, konsentrasi 100% diameter resistor 25,18 mm. Kesimpulan. Ekstrak Kencur memiliki ketahanan terhadap pertumbuhan Candida albicans secara in vitro.Kata Kunci: Ekstrak kencur, nystatin, candida albicans 
PROFIL DERMATOFITOSIS DI RUMAH SAKIT UMUM DAERAH DELI SERDANG TAHUN 2015 - 2017 TAUFIQ .; DIAN ERISYAWANTY BATUBARA
JURNAL ILMIAH MAKSITEK Vol 5 No 4 (2020): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Dermatophytosis is a superficial fungal infection of tissues containing horn substances such as the stratum corneum of theskin, hair and nails. Dermatophytosis infections are caused by dermatophytic fungi. Dermatophytosis is the biggest skinproblem in the world, especially in developing countries. This research objective is to explain the profile of dermatophytosisin Deli Serdang Regional General Hospital in 2015-2017. Penelitian ini merupakan penelitian deskriptif retrospektif.This research method is a retrospective descriptive study. Results: Based on the results of the study, the most cases ofdermatophytosis in 2015-2017 based on the classification according to location are tinea corporis, for female sex more thanmen, for the most variable age cases in 2015 occurred at the age of 45-64 years, 2016- 2017 most at the age of 25-44,based on the most patient in this case is housewife , the common treatment is a combination of systemic anti fungal, topicalanti-fungal and anti-histamine. The most cases of dermatophytosis are tinea corporis, dermatophytosis most commonlyaffects the age of group 45-64, the most genderoften affected by dermatophytosis is women compared to men,dermatophytosis most commonly affects housewives, for the treatment of more dermatophytosis patients treated withcombination therapy (systemic + topical) with anti-histamine.
PROFIL ERUPSI OBAT DI RSUD DR. PIRNGADI KOTA MEDAN TAHUN 2015 – 2017 DIZA TANZIRA; DIAN ERISYAWANTY BATUBARA
JURNAL ILMIAH MAKSITEK Vol 5 No 4 (2020): JURNAL ILMIAH MAKSITEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Indiscriminate use of drugs, the entry of new drugs almost every day on the market, and the lack of habits to report theoccurrence of drug eruption reactions, has resulted in a high incidence of drug eruption reactions occurring. Due to the lackof the latest data regarding the epidemiology of drug eruptions, this has led to need for more research. To determine theprofile of drug eruption at the regional hospital of Dr. Pirngadi in Medan City in the period of 2015-2017. Descriptive studywith cross-sectional approach from secondary data based on the medical records of in-patients and out-patients treated inthe regional hospital of Dr. Pirngadi in Medan City in the period of 2015-2017. During the period of January 2015 - December2017, there were 87 cases of drug eruption. The age group of 45-64 years (36,8%) was the commonest age group. Theincidence of drug eruption by sex, women (54,0%) is more frequent than men (46,0%). Allergic history is almost entirely notlisted on medical records (94,5%). The most frequently associated disorders was non-infectious disease (37,9%). Themaculopapular rash type is the commonest clinical manifestation of drug eruption (37,9%). The most suspected drugs thatcause the eruption was antibiotic (48,3%). The most widely used treatments were combination of corticosteroid andantihistamine (33,3%). In this study, the age group of 45-64 years was the commonest age group and women is morefrequent than men to develop drug eruption. The maculopapular rash type is the commonest clinical manifestation of drugeruption.
HUBUNGAN TINGKAT PENGETAHUAN DAN SIKAP REMAJA DI SMA MUHAMMADIYAH 02 MEDAN DENGAN KEJADIAN AKNE VULGARIS ARDA TILLA; HERVINA .; DIAN ERISYAWANTY; RINNA AZRIDA
JURNAL ILMIAH SIMANTEK Vol 4 No 4 (2020): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Akne vulgaris is a skin disease caused by inflammation of the pilosebaseus follicles and is the most common disease inadolescents aged 15-18 years. Akne vulgaris sufferers generally complain of aesthetic complaints. The lack of knowledgeand attitude of adolescents towards akne vulgaris can lead to the number of adolescents suffering from akne vulgaris. Thepurpose of this research is to find out the relationship of the level of knowledge and attitude of teenagers at SmaMuhammadiyah 02 Medan with the incident akne vulgaris. This research is descriptive of analytics with cross-sectionaldesign. The subjects in this study are students of Muhammadiyah High School 02 Medan. The technique in this study is touse simple random sampling and data analysis using chi square test. Data retrieval through questionnaire filling. Theknowledge level test of Muhammadiyah High School students 02 Medan about akne vulgaris is majority categorized enough(48.4%) and attitude test results against akne vulgaris the majority are well categorized (66.7%). Chi-Square statistical testresults, the relationship between knowledge level and attitude with akne vulgaris event was obtained a value of p = 0.877(p>0.05) and p = 0.000 (p<0.05). There is no relationship between the level of knowledge and the occurrence of aknevulgaris, and there is a relationship between attitude and the occurrence of akne vulgaris.
FAKTOR RISIKO TERJADINYA AKNE VULGARIS PADA SISWA - SISWI KELAS XII SMA HARAPAN 1 MEDAN FITRI HAFIANTY; DIAN ERISYAWANTY BATUBARA; FEBRINA DEWI PRATIWI LINGGA
JURNAL ILMIAH SIMANTEK Vol 5 No 2 (2021): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

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Abstract

Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicles which generally occurs in adolescence and canheal itself. This study aims to determine the risk factor expect acne vulgaris through several characteristics in class XIIstudens. The research method is a descriptive cross sectional study with a sample collection technique is consecutivesampling. The sample in this study is class XII students in high school of Harapan 1 Medan. This study used questionnairesand direct examination on the face and neck area to diagnose acne vulgaris in high school of Harapan 1 Medan. The resultsof the study with the majority of patients with acne vulgaris have mild degree acne (63.5%), have families who suffer fromacne vulgaris (81%), the type of food consumed is bread with butter (17.5%), normal skin type ( 42.5%), irregularly cleaningthe face (78.8%), cleaning the face <2x daily (82.5%) using special facial washing soap (87.5%), not using any cosmetics(37.5%), acne occurs before or during menstruation (70.6%), stress is quite severe (81%). From the results of this study, themost influential risk factors for the appearance of acne vulgaris are family history (81%), stress factors (81%), irregular facialcleaning (78.8%), cleaning of the face <2x a day (82.5%) and acne occurs before or during menstruation (70,6%).
Profil Erupsi Obat di RSUD Dr. Pirngadi Kota Medan Tahun 2015-2017 Diza Tanzira; Dian Erisyawanty Batubara
JURNAL PANDU HUSADA Vol 2, No 3 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/jph.v2i3.5531

Abstract

Abstrak: Penggunaan obat tanpa pandang bulu, masuknya obat baru hampir setiap hari di pasaran, dan kurangnya kebiasaan untuk melaporkan terjadinya reaksi erupsi obat, telah mengakibatkan tingginya insiden reaksi erupsi obat yang terjadi. Karena kurangnya data terbaru mengenai epidemiologi erupsi obat, hal ini menyebabkan perlunya penelitian lebih lanjut. Penelitian ini bertujuan untuk mengetahui profil erupsi obat di rumah sakit daerah Dr. Pirngadi di Kota Medan pada periode 2015-2017.  Studi deskriptif dengan pendekatan cross sectional dari data sekunder berdasarkan rekam medis pasien dalam dan luar pasien yang dirawat di rumah sakit umum daerah (RSUD) Dr. Pirngadi Kota Medan periode 2015-2017.  Selama periode Januari 2015 - Desember 2017, ada 87 kasus erupsi narkoba. Kelompok usia 45-64 tahun (36,8%) merupakan kelompok usia yang paling umum. Insiden erupsi obat berdasarkan jenis kelamin, wanita (54,0%) lebih sering terjadi daripada pria (46,0%). Riwayat alergi hampir seluruhnya tidak tercantum dalam rekam medis (94,5%).  Gangguan yang paling sering dikaitkan adalah penyakit tidak menular (37,9%). Jenis ruam makulopapular adalah manifestasi klinis paling umum dari erupsi obat (37,9%). Obat yang paling dicurigai menyebabkan erupsi adalah antibiotik (48,3%). Perawatan yang paling banyak digunakan adalah kombinasi kortikosteroid dan antihistamin (33,3%). Dalam penelitian ini,  kelompok usia 45-64 tahun adalah kelompok usia yang paling umum dan wanita lebih sering daripada pria untuk mengembangkan erupsi obat. Jenis ruam makulopapular adalah manifestasi klinis paling umum dari erupsi obat.
Co-Authors Amanda, Alya Ance Roslina Annisah, Rati ARDA TILLA Diza Tanzira DIZA TANZIRA FITRI HAFIANTY Hervina, Hervina LINGGA, FEBRINA DEWI PRATIWI RINNA AZRIDA TAUFIQ .