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All Journal Nusantara Hasana Journal International Journal of Health and Pharmaceutical (IJHP) Jurnal Ilmu Multidisplin
Putri Rahmawati, Riana
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UJI TOKSISITAS AKUT EKSTRAK ETANOL 70% KULIT PISANG KEPOK KUNING (Musa paradisiaca L.) TERHADAP LARVA UDANG (Artemia salina Leach) MENGGUNAKAN METODE Brine Shrimp Lethality Test (BSLT) Hasriyani, Hasriyani; Putri Rahmawati, Riana; Putri Utami, Meira
Nusantara Hasana Journal Vol. 4 No. 9 (2025): Nusantara Hasana Journal, February 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i9.1366

Abstract

Yellow kepok banana is a horticultural plant native to Indonesia in Southeast Asia, which is used as an antimicrobial, antihypertensive, antiallergic, antioxidant, antianalgesic, diuretic, hypolipidemic and vasodilator. Yellow kepok banana peel is a waste of kepok banana which contains high antioxidant compounds such as phenol, catecholamide, carotene and flavonoids, polyphenols, vitamin C, and tannins. Method: Experimental research design, 180 Artemia Shrimp Larvae were divided into 5 concentration groups consisting of 10 shrimp larvae with 3 replications of concentration groups, namely 250, 500, 750, 1,000 ppm. Results: Phytochemical screening of 70% ethanol extract of yellow kepok banana peel contains active compounds of alkaloids, flavonoids, saponins, and tannins. Observations for 24 hours, at a concentration of 250 ppm there was a percentage of death of 63%, at a concentration of 500 ppm of 73%, at a concentration of 750 ppm of 87% and a concentration of 1000 ppm of 97%. The LC50 value obtained was 38.899 ppm. So the highest dose is 1,000 ppm and it can be stated that the yellow banana peel extract in this study was highly toxic to Artemia salina larvae test animals so that it can be used as an anti-cancer. Conclusion: Ethanol extract of 70% yellow banana peel has the potential for acute toxicity to Artemia Shrimp Larvae using the (BSLT) method because the LC50 value was <50 µg/ml.
AKTIVITAS BIOLARVASIDA EKSTRAK ETANOL SEREH WANGI (Cymbopogon nardus L) TERHADAP MORTALITAS LARVA AEDES AEGYPTI Putri Rahmawati, Riana; Hasriyani, Hasriyani; Nisrina Absor, Farah
Nusantara Hasana Journal Vol. 4 No. 9 (2025): Nusantara Hasana Journal, February 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i9.1370

Abstract

Aedes aegypti mosquitoes  are the main vector of the spread of dengue hemorrhagic fever (DHF). These mosquito controls are often carried out with synthetic insecticides, but their use can lead to resistance and negative impacts on the environment. Therefore, a more environmentally friendly control alternative is needed, one of which is with natural biolarvicides. One example of a plant that has the potential to be a biolarvicide is citronella (Cymbopogon nardus L). This study aims to determine the biolarvicide activity of citronella ethanol extract (Cymbopogon nardus L) on the mortality of Aedes aegypti larvae  and determine the Lethal Concentration 50 (LC50) value. This research was carried out using experimental methods and data analysis techniques used, namely quantitative by calculating the LC valueof 50 using the probit analysis test on SPSS.  The results of the average percentage of mortality of Aedes aegypti larvae in group 1 (5%) was 61.3%, group 2 (10%) was 86.6%, and group 3 (15%) was 96.6%. The LC value of 50 from citronella ethanol extract (Cymbopogon nardus L) on the mortality of Aedes aegypti larvae was 3.531%. Citronella ethanol extract (Cymbopogon nardus L) has been shown to have natural biolarvicide effectiveness as the concentration of the extract increases.
Formulasi dan Uji Aktivitas Sediaan Lilin Aromaterapi Minyak Atsiri Daun Nilam (Pogostemon Cablin Benth) terhadap Nyamuk Aedes Aegypti Bagaskara; Putri Rahmawati, Riana; Jayanti Besan, Emma
Jurnal Ilmu Multidisiplin Vol. 4 No. 1 (2025): Jurnal Ilmu Multidisplin (April–Mei 2025)
Publisher : Green Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38035/jim.v4i1.897

Abstract

Lilin aromaterapi salah satu sediaan aromaterapi yang di aplikasikan dengan cara dihirup dari uap yang dihasilkan sediaan lilin aromaterapi apabila di bakar. Penggunaan lilin aromaterapi sebagai pengusir nyamuk sering digunakan karena sifatnya yang hemat energi dan tidak memerlukan listrik. Penggunaan insektisida alami lebih aman dibandingkan insektisida sintesis/kimia. Penggunaan lilin aromaterapi dapat menggantikan penggunaan antinyamuk yang berbahan insektisida sintesis/kimia. Daun nilam (Pogostemon cablin Benth) memiliki kandungan Patchouli alkohol yang dimanfaatkan sebagai antinyamuk dan juga sebagai aromaterapi. Penelitian ini bermaksud untuk merumuskan formulasi lilin aromaterapi yang dapat berfungsi sebagai antinyamuk yang berbahan dasar minyak atsiri daun nilam. Metode yang diterapkan dalam pengujian ini adalah eksperimen laboratorium. Proses pembuatan minyak atsiri ddiperoleh melalui proses destilasi, sementara pembentukkan lilin aromaterapi dilakukan melalui teknik pelelehan. Produk lilin arometarapi diformulasikan melalui 4 formulasi di antaranya : formulasi 0 sebagai kontrol negatif, formulasi 1,2 dan 3 menggunakan zat aktif minyak atsiri dengan konsentrasi : 4%, 6% dan 8%., sedangkan formulasi 4 sediaan lilin aromaterapi merek X sebagai kontrol positif. Hasil lilin kemudian dilaksanakan uji mutu fisik untuk mencakup aspek uji organoleptik, uji waktu bakar, uji aktivitas pada nyamuk, uji titik leleh serta pengujian kadar air. Berdasarkan hasil penelitian daun nilam yang menghasilkan minyak atsiri dapat dimanfaatkam untuk pembuatan lilin aromaterapi.
Antibacterial Effectiveness Test Of Kersen Leaf Extract Lotion (Muntingia Calabura L.) Against Staphylococcus Aureus Using Disc Diffusion Method Nisa, Sofiyatun; Putri Rahmawati, Riana; Tri Sukoharjanti, Bintari
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 3 (2025): August 2025 (Indonesia - Malaysia)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i3.434

Abstract

Increasing antibiotic resistance, especially in Staphylococcus aureus, has prompted the search for safer and more effective antibacterial alternatives. Cherry leaves (Muntingia calabura L.) can be used as an antibacterial and contain secondary metabolites flavonoids, alkaloids, and tannins. This study aims to formulate an ethanol extract of cherry leaves in the form of an antibacterial lotion and evaluate its effectiveness against Staphylococcus aureus using the disc diffusion method. This study used a laboratory experimental design with concentrations of ethanol extract of cherry leaves of 5%, 10%, and 15%. The antibacterial effectiveness test was carried out by measuring the growth inhibition zone of Staphylococcus aureus. Evaluation of the physical quality of the lotion included organoleptic tests, homogeneity, pH, spreadability, and viscosity to ensure the stability of the formulation. The irritation test was carried out using the patch test method for 24 hours to assess the safety of using the lotion on the skin. The results of the study on F1 showed an inhibition zone of 10.67 mm, an inhibition zone on F2 of 11 mm, an inhibition zone on F3 of 11.33 mm and in the positive control had an inhibition zone of 12.67 mm. The most optimal concentration in inhibiting the growth of Staphylococcus aureus bacteria was at concentration F3 (15%).
Co-Authors Bagaskara Hasriyani Hasriyani, Hasriyani Jayanti Besan, Emma Nisa, Sofiyatun Nisrina Absor, Farah Putri Utami, Meira Tri Sukoharjanti, Bintari