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All Journal Jurnal Biologi Tropis JFL : Jurnal Farmasi Lampung DEVOTE: Jurnal Pengabdian Masyarakat Global Benzena Pharmaceutical Scientific Journal
Saputri, Alip Desi Suyono
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Environmental Science Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Other

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PENGARUH METODE EKSTRAKSI DAN PELARUT TERHADAP KANDUNGAN METABOLIT SEKUNDER DAN AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN INSULIN (Smallanthus sonchifolius): SOLVENTS EFFECT AND EXTRACTION METHODS ON SECONDARY METABOLITE CONTENT AND ANTIOXIDANT ACTIVITY OF INSULIN LEAF EXTRACT (Smallanthus sonchifolius) Saputri, Alip Desi Suyono; Sa'ad, Muhammad; Maharani, Putri; Prahesti, Maya Tesa
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1629

Abstract

Insulin leaves (Smallanthus sonchifolius) are reported to have strong antioxidant activity. This activity comes from the content of secondary metabolite compounds such as phenolics, flavonoids, tannins, as well as anthocyanin and betacyanin pigments. To obtain the phytochemical content of a plant, an extraction process is carried out. The extraction method and solvent are factors that influence the amount of phytochemical content in the extract. There has been no research analyzing effective methods and solvents for extracting insulin leaves to obtain the highest antioxidant effect. This research was conducted to determine the effect of extraction methods and solvents on the antioxidant activity of insulin leaf extract. Maceration and digestion methods with distilled water, 50% ethanol and 96% ethanol were used in the extraction of insulin leaf simplicia in this study. Samples obtained were Aquadest Macerated Extract (EMA), 50% Ethanol Macerated Extract (EME50), 96% Ethanol Macerated Extract (EME96), Aquadest Digested Extract (EDA), 50% Ethanol Digested Extract (EDE50), and 96% Ethanol Digested Extract (EDE96). Testing the antioxidant activity of each sample used the DPPH method by calculating the IC50 value and using Quercetin as a positive control. Data analysis was carried out using one way anova analysis. The results show that the choice of solvent and extraction method influences the antioxidant activity of the extract. The IC50 values ​​for each extract from low to high are: EDA, EDE50, EMA, EDE96, EME50, and EME96, with values: 20.06ppm; 22.44ppm; 23.77ppm; 23.84ppm; 24.55ppm; and 27.71ppm. It can be concluded that the method and solvent to obtain the best antioxidant activity from insulin leaves (Smallanthus sonchifolius) is extraction using the digestion method with distilled water as a solvent (p<0,05). Keywords:  antioxidant, digestion, insulin leaf, maceration, solvent  
PELATIHAN DIGITAL MARKETING SEBAGAI UPAYA PENGEMBANGAN KETERAMPILAN PELAKU UMKM DI POLOKARTO, SUKOHARJO Semartini, Atur; Saputri, Alip Desi Suyono
Devote: Jurnal Pengabdian Masyarakat Global Vol. 4 No. 2 (2025): Devote : Jurnal Pengabdian Masyarakat Global, Juni 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/devote.v4i2.3758

Abstract

Micro, Small, and Medium Enterprises (MSMEs) play an important role in the welfare of society and in economic development in many countries, including Indonesia. However, in practice, MSMEs often face obstacles in advancing and growing their businesses. One common challenge is in product promotion. This Community Service activity aims to provide knowledge and training to MSME actors in Polokarto village regarding digital marketing to help them promote their businesses more widely. This activity was conducted through counseling and training methods, which also facilitated discussions between the participants and the service team. Before the activity began, participants were given a pre-test to assess their initial knowledge of digital marketing. After the activity concluded, a post-test was administered to evaluate the increase in knowledge. Based on the pre-test and post-test results, there was an average score increase of 28.750. Additionally, based on data analysis, a p-value of < 0.05 was obtained. This indicates that the counseling and training had a significant impact on participants’ knowledge of digital marketing. With this digital marketing training and counseling, MSME actors can overcome promotional challenges, making their products more widely known and enabling them to survive in a competitive market.
Ethnopharmaceutical Study of Plants as an Alternative Treatment Gastritis Baluwarti Society Risma, Nindita Yoan; Saputri, Alip Desi Suyono; Anggraini, Truly Dian
Jurnal Biologi Tropis Vol. 24 No. 2 (2024): April - Juni
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i2.6904

Abstract

The Baluwarti community is a community that lives around the Surakarta Hadiningrat Palace with consist of princes relatives, courtiers, and ordinary people. Baluwarti community to currently still carrying out traditional medicine traditions by utilizing medicinal plants as a treatment in Baluwarti village, gastritis is included in the category of 15 diseases frequent highs. This research is an ethnopharmaceutical research aimed at to find out the local name of the plant, the part used, the way of processing, the rules usage, and treatment methods used as an alternative treatment of gastritis carried out by the community around the Surakarta Hadiningrat Palace. This research is descriptive research that uses quantitative methods. The analysis parameters used are: Use Value (UV), Informant Consensus Factor (ICF), Fidelity Level (FL), and Plant Part Value (PPV). Sampling technique using snowball sampling through open ended interview with the community around the Surakarta Hadiningrat Palace. Based on results interviews with 17 informants found 13 types of medicinal plants used as alternatives treatment of gastritis includes African plants, neem plants, cassava genderuwo, white turmeric, temulawak, cassava, and ginger are processed by boiling. In addition, breadfruit pace and white duwet that can be eaten immediately. Turmeric by processing is ground and grated, as well as aloe vera that is taken mucus using a spoon. The result of the ICF value obtained disease gastritis with a value of 0.25. Plant species that have the highest UV value with a value 0.647 and the highest FL yield of 64.70% is turmeric (Curcuma longa L.) while the PPV value obtained the use of plant parts that are most often used as medicinal materials traditional is 30% rhizome, 18% leaf, 12% fruit, 12% tuber, and 6% mucus.
Effect of Guava Fruit Aqueous Extract on Haematological Profile of Carbon Tetrachloride Induced Rat Rahmawati, Aulia Nur; Lestari, Mastuti Widi; Saputri, Alip Desi Suyono; Berliana, Adinda Aisyah; Fattany, Davan Nur; Cahyaningrum, Oktavia Fajar
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8066

Abstract

Psidium guajava or guava have many potential value, including as antioxidant. Psidium guajava fruits have been reported that contain essential oil, flavonoid, polyphenol, ascorbic acid, dan tocopherol. This study aims to investigate weight gain and heamatological alteration as an effect from administration of red guava fruit extract in male wistar rats after carbon tetrachloride. This study was experimental design using male wistar rats as an experimental animals. The results of the study were red guava fruit aqueous extract can control weight gain in model animal, increasing of LYM, MCMC dan WBC. It indicated that Psidium guajava fruit is potentially be able to be used as an pharmaceutical product because of its antioxidant ability.
PENETAPAN KADAR FLAVONOID REBUSAN DAN SEDUHAN DAUN TAPAK LIMAN (Elephantopus scaber) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Multi, Bryan Dwi; Saputri, Alip Desi Suyono; Sa'ad, Muhammad
BENZENA Pharmaceutical Scientific Journal Vol 3 No 01 (2024): BENZENA PHARMACEUTICAL SCIENTIFIC JOURNAL
Publisher : Universitas Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31941/benzena.v3i01.4425

Abstract

Latar bekalang :  Banyak penduduk Indonesia yang menggunakan tanaman obat atau jamu baik untuk menjaga kesehatan maupun untuk pengobatan karena sakit. Salah satu tanaman obat yang sering dikonsumsi oleh masyarakat yaitu tanaman tapak liman (Elephantopus scaber). Tanaman Tapak liman (Elephantopus scaber) diketahui mempunyai kandungan flavonoid yang cukup tinggi. Masyarakat Indonesia dalam mengkonsumsi tanaman obat menggunakan cara direbus dan diseduh.Tujuan:Tujuan dari penelitian ini adalah untuk mengetahui kadar flavonoid tertinggi pada dua metode ekstraksi (rebusan dan seduhan) menggunakan Spektrofotometri UV-Vis.Metode:Metode penelitian ini berupa metode eksperimental. Uji kualitatif dilakukan dengan uji KLT dan menghasilkan bercak dibandingkan dengan standar kuersetin. Uji kuantitatif dilakukan dengan penetapan kadar flavonoid total rebusan dan seduhan simplisia daun tapak liman dengan Spektrofotometri UV-Vis.Hasil: Hasil penetapan kadar flavonoid total didapatkan sebesar 2,448 ± 0,1597 mgQE/100ml dengan %KV 0,65 pada metode rebusan. Pada seduhan simplisia daun tapak liman kadar yang diperoleh sebesar 0,531 ± 0,0096 mgQE/100ml dengan %KV 1,81. Uji statistik menunjukkan nilai signifikansi dari perbedaan kadar flavonoid (p value 0,000 < 0,05).Kesimpulan: Kesimpulan pada penelitian ini terdapat perbedaan kadar flavonoid yang signifikan antara rebusan dan seduhan daun tapak liman. Metode rebusan memiliki kandungan flavonoid lebih besar dibanding metode seduhan.
Co-Authors Anggraini, Truly Dian Aulia Nur Rahmawati Berliana, Adinda Aisyah Cahyaningrum, Oktavia Fajar Fattany, Davan Nur Mastuti Widi Lestari, Mastuti Widi Muhammad Sa'ad Multi, Bryan Dwi Prahesti, Maya Tesa Putri Maharani Risma, Nindita Yoan Sa'ad, Muhammad Semartini, Atur