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All Journal Jurnal Pendidikan Matematika dan IPA Jurnal Mandala Pharmacon Indonesia SITAWA : Jurnal Farmasi Sains dan Obat Tradisional FASKES : Jurnal Farmasi, Kesehatan, dan Sains
Fera, Okta
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Physics Public Health

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Potential of Endophytic Bacteria from Pauh Stems (Mangifera sumatrana Miq) as Antimicrobials Zaunit, Muthia Miranda; Verawati, Verawati; Anela Putri, Suci; Fera, Okta
FASKES : Jurnal Farmasi, Kesehatan, dan Sains Vol. 1 No. 2 (2023): Bulan November 2023 Faskes : Jurnal Farmasi, Kesehatan dan Sains
Publisher : Program Studi Farmasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32665/faskes.v1i3.2425

Abstract

Background: Endophytic bacteria are microorganisms whose life cycle resides in plant tissue without causing damage to the host and are capable of producing bioactive compounds, one of which is antibacterial compounds from the papuh plant (Mangifera sumatrana Miq.). Objective: This study aims to isolate and test the antimicrobial activity of endophytic bacteria in the stems against Staphylococcus aureus, Escherichia coli and Candida albicans and to carry out molecular identification using the 16S rRNA gene against endophytic bacteria that have the greatest antimicrobial power. Method: Antimicrobial activity testing was carried out using the disc diffusion method. Results: The results of the characteristics of endophytic bacteria obtained using the planting method were 6 isolates, namely 4 isolates from the outer stem (BL1, BL2, BL3, and BL4) and 2 isolates from the inner stem (BD1 and BD2). The results of the antimicrobial activity test for isolates BL2 and BL3 against Staphylococcus aureus found an inhibition zone of 13.20 mm and 12.05 mm, whereas against Candida albicans and Escherichia coli, they had no antimicrobial activity. The results of molecular identification show that the BL2 is Bacillus altitudinis. Conclusions and suggestions: Bacterial isolates from pauh stems have the potential to be antibacterial.
Kajian Penggunaan Obat Antihipertensi Pada Pasien Stroke Di RSUD DR. Rasidin Padang Periode April-Desember 2021 Azyenela, Lola; Fera, Okta; Nofiandi, Dedi; Fauziah, Nur
Jurnal Mandala Pharmacon Indonesia Vol. 10 No. 1 (2024): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v10i1.508

Abstract

Terapi antihipertensi merupakan salah satu terapi preventif yang diterima pasien stroke terutama pasien stroke iskemik. Terapi antihipertensi yang tidak tepat pada pasien stroke, dapat menyebabkan perburukan kondisi pasien. Tujuan penelitian ini adalah mengkaji ketepatan penggunaan obat antihipertensi pada pasien stroke di RSUD Dr. Rasidin Padang periode tahun 2021, yang meliputi, tepat indikasi, tepat pasien, tepat obat, tepat dosis,dan tepat rute pemberian obat. Jenis penelitian ini adalah deskriptif observasional dengan pengambilan data secara retrospektif dari data rekam medis pasien. Kriteria inklusi pada penelitian ini adalah pasien rawat jalan yang didiagnosa stroke disertai hipertensi dengan atau tanpa komplikasi penyakit lain yang mendapatkan terapi antihipertensi. Ketepatan penggunaan obat antihipertensi dilakukan secara deskriptif, dengan cara membandingkan data yang didapat dengan rujukan yang digunakan, meliputi JNC VIII, Guideline Stroke yang dikeluarkan oleh PERDOSSI tahun 2011 serta Formularium Rumah Sakit RSUD Dr. Rasidin Padang. Hasil penelitian ini menunjukkan bahwa ketepatan indikasi dan pasien sebanyak 60 pasien atau 100%, ketepatan penggunaan obat adalah sebanyak 57 pasien atau 95%, ketepatan penggunaan dosis adalah 100% serta ketepatan rute pemberian obat adalah sebanyak 60 pasien atau 100%. Jenis ketidaktepatan yang ditemukan adalah pemilihan kombinasi antihipertensi yang tidak tepat yaitu penggunaan kombinasi obat dari golongan yang sama. Simpulan penelitian ini adalah perlunya evaluasi penggunaan obat oleh apoteker untuk meningkatkan ketepatan penggunaan obat di RSUD Dr. Rasidin Padang.
ANALYSIS OF DISEASE SEVERITY ON CITRUS LEAVES (CITRUS spp.) USING IMAGEJ AND PLANTIX SOFTWARE Hasanah, Melly Rya; Rosadi, Imam; Oktavianingsih, Linda; Fitriani, Nur Indah; Fera, Okta; Addin, Rosita; Ayuni, Cici Lis Qurrotun; Muhammadiyah, Muhammadiyah
Jurnal Pendidikan Matematika dan IPA Vol 14, No 2 (2023): July 2023
Publisher : Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/jpmipa.v14i2.65294

Abstract

The purpose of this case study is to determine the severity of citrus leaves using Plantix software and ImageJ software. Based on the results of this case study, it was found that the severity of the disease using ImageJ software was on citrus leaves at the first location (10.641%), citrus leaves at the second location (53.278%), and citrus leaves at the third location (15.828%) which were generally the fruit plants caused by fungi and based on the results of Plantix software data, diseases in the first, second, and third locations of citrus leaves were caused by bacterial diseases. Based on the results of bacterial cell culture, isolates were found to be round white in color with a slight yellowness which is a characteristic of Xanthomonas axonopodis bacteria with a large number of ±12 colonies and a smaller number of ±35 colonies. Using software and imageJ can help farmers to find out the types of pests that attack citrus plants so that farmers can handle plants to minimize damage to citrus plants caused by pests.
Perbandingan Kandungan Fenolik Total Dan Antioksidan Ekstrak Akar Tapak Liman (Elephantopus scaber Linn Dan Elephantopus mollis Kunth) Mega Yulia; Adelya, Melta; Nurdin, Hazli; Fera, Okta
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 5 No. 1 (2026): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v5i1.227

Abstract

Two species of tapak liman plants commonly known in Indonesia, Elephantopus scaber Linn and Elephantopus mollis Kunth, belonging to the Asteraceae family, are known to have many health benefits. Tapak liman plants produce secondary metabolites such as phenolics. Phenolic compounds are known to act as antioxidants. This study aims to determine the comparison of total phenolic content in ethanol extracts of E. scaber and E. mollis roots, as well as the comparison of antioxidant activity between E. scaber and E. mollis roots using the DPPH method. The results of phytochemical screening of ethanol extracts from E. scaber and E. mollis roots revealed the presence of phenolic compounds, flavonoids, and terpenoids. The total phenolic compound content in E. scaber samples was determined to be 4.31% and in E. mollis samples to be 2.35%. The determination of the maximum absorption wavelength of DPPH at 35 µg/ml using a UV-Vis spectrophotometer showed a maximum absorption wavelength of 519 nm with an absorbance of 0.610. The antioxidant activity of the ethanol extract of E. scaber roots was obtained with an IC50 of 131.4431 µg/ml, while that of E. mollis roots was 106.4321 µg/ml. Based on these results, it can be concluded that the total phenolic content of the ethanol extract of E. scaber roots is higher than that of E. mollis roots. Furthermore, the antioxidant activity of the E. scaber root extract is stronger than that of the E. mollis root extract, but both still fall into the same category, namely the moderate category. Based on statistical tests using the T test, it shows that the significant differences for phenolic content and not significant for antioxidant activity (p < 0.05).
Co-Authors Addin, Rosita Adelya, Melta Anela Putri, Suci Ayuni, Cici Lis Qurrotun Azyenela, Lola Fitriani, Nur Indah Hasanah, Melly Rya Hazli Nurdin Imam Rosadi Linda Oktavianingsih Mega Yulia Muhammadiyah, Muhammadiyah Nofiandi, Dedi Nur Fauziah Verawati Verawati Zaunit, Muthia Miranda