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All Journal JFIOnline JURNAL FARMASIMED (JFM) Unri Conference Series: Community Engagement
Husori, Dadang Irfan
Departemen Farmakologi, Fakultas Farmasi, Universitas Sumatera Utara, Medan
Humanities Health Professions Medicine & Pharmacology

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Aktivitas Antelmintik Ekstrak Air Daun Puguntano Curanga fel-terrae (Lour.) Merr. Patilaya, Popi; Husori, Dadang Irfan
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 7, No 4 (2015)
Publisher : Indonesian Research Gateway

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Abstract

Penelitian ini dilakukan untuk menentukan aktivitas antelmintik ekstrak air daun puguntano (Curanga fel-terrae). Daun puguntano diekstraksi dalam air suling dengan pendidihan selama 10 menit. Cacing Pheretima posthuma dipaparkan ke dalam ekstrak air daun puguntano konsentrasi 10, 20, 30, dan 40 mg/ml selama 5 jam. Larutan albendazol 10 mg/ml dan salin masing-masing digunakan sebagai kontrol positif dan kontrol negatif. Aktivitas antelmintik ditentukan dengan mengamati waktu paralisis dan kematian Pheretima Posthuma. Hasil penelitian menunjukkan bahwa ekstrak air daun puguntano konsentrasi 20 - 40 mg/ml menyebabkan paralisis dan kematian Pheretima Posthuma masing-masing antara 14,27 - 36,82 menit dan 18,69 - 42,47 menit. Penelitian ini menunjukkan bahwa ekstrak air daun puguntano memiliki potensi aktivitas antelmintik.
Aktivitas Antelmintik Ekstrak Air Daun Puguntano Curanga fel-terrae (Lour.) Merr. Patilaya, Popi; Husori, Dadang Irfan
Jurnal Farmasi Indonesia Vol 7, No 4 (2015)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfi.v7i4.195

Abstract

Penelitian ini dilakukan untuk menentukan aktivitas antelmintik ekstrak air daun puguntano (Curanga fel-terrae). Daun puguntano diekstraksi dalam air suling dengan pendidihan selama 10 menit. Cacing Pheretima posthuma dipaparkan ke dalam ekstrak air daun puguntano konsentrasi 10, 20, 30, dan 40 mg/ml selama 5 jam. Larutan albendazol 10 mg/ml dan salin masing-masing digunakan sebagai kontrol positif dan kontrol negatif. Aktivitas antelmintik ditentukan dengan mengamati waktu paralisis dan kematian Pheretima Posthuma. Hasil penelitian menunjukkan bahwa ekstrak air daun puguntano konsentrasi 20 - 40 mg/ml menyebabkan paralisis dan kematian Pheretima Posthuma masing-masing antara 14,27 - 36,82 menit dan 18,69 - 42,47 menit. Penelitian ini menunjukkan bahwa ekstrak air daun puguntano memiliki potensi aktivitas antelmintik.
Edukasi Diabetes Melitus dan Pemeriksaan Glukosa Darah Acak serta Asam Urat Sebagai Upaya Preventif Penyakit Komorbid Covid-19 Urip Harahap; Ade Sri Rohani; Hari Ronaldo Tanjung; Dadang Irfan Husori; Khairunnisa Khairunnisa; Embun Suci Nasution
Unri Conference Series: Community Engagement Vol 3 (2021): Seminar Nasional Pemberdayaan Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/unricsce.3.450-456

Abstract

Diabetes mellitus is one of the comorbid Covid-19, leading cause of death after kidney and heart disease. Lack of understanding related to diabetes mellitus and its prevention in the community in Karya Jati sub-district, North Binjai, Binjai City and the lack of medical check-up including random blood glucose and uric acid levels make education about diabetes mellitus necessary. This program aimed to increase participants knowledge in Karya Jati sub-district, North Binjai, Binjai City about diabetes mellitus, signs/symptoms, prevention, risk factor, life style, and diabetes as covid-19 comorbidity. This program was carried out using the Active Participant Learning Method (CBPA) and medical check-up including random blood glucose and uric acid levels, as well as monitoring and evaluation of community service. Based on T-Test, the results of the pre-test and post-test analysis showed an increase in participants' knowledge about diabetes significantly (p<0.05).
Effect of Pharmaceutical Care on Adherence, Drug-Related Problems, Cost of Illness, and Quality of Life in Hemodialysis Outpatients Annas Reza; Embun Suci Nasution; Dadang Irfan Husori
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.4093

Abstract

Background: Complex treatment regimens in hemodialysis patients often lead to drug-related problems (DRPs), non-adherence, diminished quality of life, and a high medical cost burden. This presents an opportunity to implement pharmaceutical care to optimize patients' therapeutic outcomes. Objective: This study aimed to analyze medication adherence, drug-related problems (DRPs), cost of illness (COI), and quality of life in hemodialysis patients following a pharmacist-led pharmaceutical care intervention. Methods: A single-group, quasi-experimental study with a pre-test and post-test design was conducted using total sampling from March to June 2026 at Meuraxa Regional General Hospital, Banda Aceh. The pharmaceutical care intervention included medication reconciliation, pharmacotherapy review,individual counseling using the "teach-back" method, and medication monitoring. Adherence was assessed using the Medication Adherence Report Scale-5 (MARS-5) questionnaire; DRPs were evaluated using the Pharmaceutical Care Network Europe (PCNE) classification (version 9.1); COI was analyzed to determine the magnitude and composition of direct medical costs; and quality of life was measured using the WHOQOL-BREF questionnaire. Data were analyzed using non-parametric tests, specifically the Wilcoxon signed-rank test and the Friedman test (for COI). Results: Patient adherence significantly increased by 67.6% (p<0.001), and the incidence of DRPs decreased from 63 to 32 occurrences (p=0.022). Patients' quality of life improved by 54.2% (p<0.001). The difference in costs between the pre-test and post-test was not statistically significant after Bonferroni correction (p=0.045), although the cost per dialysis visit decreased by 5.8%. Conclusion: Pharmaceutical care can improve medication adherence, reduce the incidence of DRPs, and enhance the quality of life of hemodialysis patients. Controlled studies are required to establish causality and economic benefits.
Co-Authors Ade Sri Rohani Annas Reza Embun Suci Nasution Khairunnisa Khairunnisa Patilaya, Popi Patilaya, Popi Tanjung, Hari Ronaldo Urip Harahap