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Identification of Atherosclerosis Based on The Differences in Cholesterol and Creatinine in Indonesia with Multivariate Analysis of Variance Maulana Achiar, Anshari Luthfi; Aidi, Muhammad Nur; Kurnia, Anang; Widoretno, Widoretno
EKSAKTA: Berkala Ilmiah Bidang MIPA Vol. 24 No. 03 (2023): Eksakta : Berkala Ilmiah Bidang MIPA (E-ISSN : 2549-7464)
Publisher : Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Negeri Padang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/eksakta/vol23-iss03/417

Abstract

Atherosclerosis is a chronic inflammatory disease indicated by plaque build-up in the arteries due to increased total cholesterol, low-density lipoproteins (LDL), triglycerides, and decreased high-density lipoproteins (HDL). It is also associated with disruption of renal function high creatinine blood level. This study aims to identify atherosclerosis based on differences in total cholesterol, HDL, LDL, triglycerides, and creatinine levels in 35.509 residents from 33 provinces and rural-urban areas in Indonesia. This study uses two-factor MANOVA where the province and rural-urban are the factors, followed by ANOVA and Tukey's test. Results show differences between total cholesterol, HDL, LDL, triglyceride, and creatinine levels of the residents among provinces and rural-urban areas. The Residents from Bangka Belitung and North Sulawesi provinces have the highest risk of atherosclerosis, and Jambi province has the most balanced condition. Urban residents tend to be at risk for atherosclerosis due to high levels of LDL, while rural residents are at risk by low HDL or high creatinine levels
Dyslipidemia in Renal Dysfunction among Non-diabetic Individuals from the 2019 Indonesian Cohort Study: A Cross-Sectional Study Retiaty, Fifi; Dany, Frans; Ernawati, Fitrah; Nurjanah, Nunung; Efriwati, Eriwati; Arifin, Aya Yuriestia; Sundari, Dian; Prihatini, Mutiara; Widoretno, Widoretno; Sahara, Ema; Imanningsih, Nelis; Herawati, Ade Nugraheni
Jurnal Gizi dan Pangan Vol. 18 No. 2 (2023)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25182/jgp.2023.18.2.71-78

Abstract

The aim of this study was to investigate the relationship between dyslipidemia and the estimated Glomerular Filtration Rate (eGFR) values in a healthy population without a history of diabetes mellitus. Data were part of the cohort study database of 2019. Data analysis was perfomed using descriptive and inferential statistics with linear regression in 893 of 1,545 non-diabetic participants. The results showed that the average cholesterol levels, High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), and triglycerides were 196.75, 48.71, 123.37, and 109.56 mg/dl, respectively, and the average eGFR level of the respondents was 98.47±15.50 mg/dl. This study found that age, HDL levels, and LDL levels had a significant relationship with eGFR (p<0.05). It was concluded that increasing age and LDL levels and decreasing HDL levels would decrease eGFR.