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Management and Complications of Cerebral Malaria Putra, Rifky Sandya Rakadi; Retnaningsih, Ekawaty; Kadarisma, Shofia; Sesariana, Mayumi Agestia; Syalsabila, Dara Pitra; Karlina, Fairuz
PROMOTOR Vol. 8 No. 4 (2025): AGUSTUS
Publisher : Universitas Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/pro.v8i4.1287

Abstract

Malaria remains a major public health issue in Indonesia, particularly in regions with high endemicity such as Papua and East Nusa Tenggara. According to the 2010 Basic Health Research (Riskesdas), the national malaria prevalence was 0.6%, with the highest rates recorded in West Papua (10.6%), Papua (10.1%), and East Nusa Tenggara (4.4%). In 2023, Papua continued to be identified as a region with high endemicity, while West Nusa Tenggara was classified as having low endemicity. Severe malaria, including cerebral malaria, is a serious complication characterized by central nervous system dysfunction, such as decline consciousness, seizures, and neurocognitive impairment, as well as systemic complications such as anemia, hypoglycemia, metabolic acidosis, and hepatosplenomegaly. Management of severe malaria requires the administration of antimalarial injections, such as intravenous artesunate as the first line therapy or quinine drip if artesunate is unavailable, performed in healthcare facilities equipped with inpatient care and intensive monitoring. This procedure involves close monitoring of blood pressure, temperature, blood glucose levels, and organ function to prevent further complications. The prognosis of cerebral malaria patients depends on the timeliness of diagnosis and proper management, while comprehensive care can improve recovery rates and reduce long-term risks. Preventive efforts through strengthening healthcare facilities in endemic areas and increasing public awareness is crucial to reduce the incidence of severe malaria and its adverse effects.
A Complete Guide to Hyperthyroidism: What You Need to Know Yahya, Najla Aulia; Nugraha , Kadek Nandita; Hardyningrat, Baiq Inna Dwi; Kirana, Devi Chandra; Kadarisma, Shofia; Nurhaliza , Siti; Ishlahi , Salsabila Dinda Nuril; Makbul, Ini Hidayat; Farras , Afif; Amanullah , Mohammad Sany Rosafi
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.7930

Abstract

Hyperthyroidism is a condition characterized by excessive thyroid gland activity, leading to an overproduction of thyroid hormones, namely thyroxine (T4) and triiodothyronine (T3). These hormones play a crucial role in regulating the body's metabolism, and their overproduction can affect various bodily functions. The aim of this article is to provide a comprehensive review of the epidemiology, etiology, clinical manifestations, and management options for hyperthyroidism. The review method involves a thorough analysis of relevant literature, including observational studies, clinical trials, and other related articles, to assess various aspects of the condition. This review identifies that hyperthyroidism is more prevalent in women, particularly with increasing age, with key risk factors including autoimmune diseases, genetic disorders, and environmental exposures. Clinical manifestations vary widely, from metabolic symptoms to systemic disorders, necessitating a proper diagnostic approach. Management strategies include the use of antithyroid medications, radioactive iodine therapy, and thyroid surgery. A deep understanding of hyperthyroidism is critical for effective diagnosis and treatment, as timely and appropriate interventions can improve patient outcomes and minimize long-term complications.