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Pengaruh Ekstrak Daun Kelor (Moringa oleifera Lam.) terhadap Penyembuhan Luka Herdiani, Mirsa; Pramasari, Cristiani Nadya; Purnamasari, Cicih Bhakti
Mulawarman Dental Journal Vol 2, No 1 (2022): MOLAR Maret 2022
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/MOLAR.v2i1.5533

Abstract

Penyembuhan luka merupakan proses alami dan kompleks yang melibatkan tiga fase, inflamasi, proliferasi dan remodeling. Semakin cepat proses penyembuhan terjadi, semakin sedikit kemungkinan terjadinya keparahan dan infeksi sekunder. Beberapa agen dan zat aktif digunakan dalam mempercepat proses tersebut. Daun kelor merupakan bahan alam dengan kandungan zat aktif yang banyak digunakan sebagai anti inflamasi. Penelitian ini bertujuan untuk mengetahui apakah ekstrak daun kelor dapat mempengaruhi proses penyembuhan luka, terutama pada fase proliferasi dan remodeling. Penelitian ini menggunakan Post test only control group design. Dengan 3 kelompok perlakuan ektrak daun kelor 5%, 10% dan 15%, diaplikasikan pada hewan coba yang telah dilukai sebelumnya. Terjadinya penyembuhan luka ditandai dengan pengukuran sel fibroblas dan kolagen yang dihitung pada hari ke-3, ke-5 dan ke-7 paska perlukaan. Data dianalisa menggunakan One Way Anovadan dilanjutkan dengan uji LSD serta uji Kruskal Wallis dan dilanjutkan dengan Mann Whitney U. Hasil penelitian menunjukkan bahwa terdapat peningkatan jumlah sel fibroblas dan kolagen di daerah luka pada kelompok perlakuan. Ekstrak daun kelor 15% menunjukkan peningkatan lebih tinggi dibandingkan kelompok perlakuan lainnya. Ekstrak daun kelor berpengaruh terhadap proses penyembuhan luka.
Mandibular third molar autotransplantation in a 15-year-old patient: five-year radiographic and clinical follow-up case report Marampa, Wilman Rante; Herdiani, Mirsa; Samad, Syahril; Agustin, Sylvia
Padjadjaran Journal of Dentistry Vol 37, No 2 (2025): July 2025
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol37no2.61910

Abstract

ABSTRACT Introduction: Tooth autotransplantation is a viable treatment option for replacing extracted permanent teeth that have been damaged due to caries, trauma, and malformations. This method offers a quick and economical solution when a donor tooth is available to replace a non-restorable tooth. The purpose of this case report is to present a unique case of mandibular third molar autotransplantation performed in a 15-year-old patient, with five-year radiographic and clinical follow-up. Case report: A 15-year-old female patient presented with her parents to the emergency room at Abdul Wahab Sjahranie Regional Hospital, complaining of an unbearable toothache following a previous dental filling. Intraoral examination revealed tooth 46 with a glass ionomer cement (GIC) restoration, a positive percussion test, and no history of swelling. An orthopantomogram (OPG) examination showed a radiolucent area at the apex of tooth 46. Impacted tooth 48 was observed with periodontal tissue in good condition and an incompletely formed root. Autotransplantation was performed using tooth 48 after the extraction of tooth 46. At the five-year follow-up appointment after treatment, tooth 48 remained stable and fully functional, with no complications, including mobility or infection. Conclusion: Tooth autotransplantation is an effective option for replacing missing teeth in young patients. Long-term success can be achieved with appropriate patient selection, atraumatic surgical technique, and careful postoperative care.KEYWORDSMandible, immature teeth, third molars, autotransplantation, extraction