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Effect of Moringa Leaves Oral Supplementation on Pro-Inflammatory Cytokines in PEM Conditions Aquarista, Nita; Widyawati, Melyana Nurul; Kurnianingsih, Kurnianingsih
Indonesian Journal of Global Health Research Vol 6 No 4 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i4.3256

Abstract

Protein-Energy Malnutrition (PEM) is a nutritional problem resulting from protein or energy deficiency, often associated with the occurrence of infections. Infections due to weakened immune systems caused by protein deficiency can lead to inflammation. The flavonoid content in moringa oleifera leaf (MOL) has anti-inflammatory that can be utilized as an alternative treatment for PEM. Objective: To identified the potential of MOL as an anti-inflammatory in PEM conditions. Method: This study is a systematic literature review that were obtained through Google Scholar, ScienceDirect and PubMed databases for the last 10 years from 2012 to 2022 with a total 80 articles found based on keyword searches. References then re-selected using PICOS method, resulting in 9 articles be reviewed. The review process involves gathering pertinent information that is applicable to the study objectives and analyzing it based on population/problems, intervention or management to the case, comparating the similarities and differences, study the outcome and study design of the previous articles. Then the information will be synthesized to conclude the review. Results: The findings indicate that MOL can be used effectively for patient with PEM as an anti-inflammatory agent by reducing the secretion of pro-inflammatory cytokines such as IL-1, IL-6 and TNF-α Conclusions: Administration of oral supplementation of MOL has a positive impact as an anti-inflamatory in PEM condition.
Geographical Variations in Moringa Oleifera and Its Potential for Stunting Intervention: A Systematic Review Muryasari, Ika; Widyawati, Melyana Nurul; Kurnianingsih, Kurnianingsih; Aquarista, Nita
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.5787

Abstract

Stunting is a major global health issue, particularly in Indonesia, where malnutrition rates remain high. Poor childhood nutrition affects growth, cognition, and long-term health. Moringa oleifera is a nutrient-rich herbal supplement, but its nutritional composition varies by geography, potentially influencing its effectiveness in stunting interventions. Objective: To identify the best Moringa leaf source for extract production to support weight and height improvement in stunted children. Method: A systematic literature review (SLR) was conducted using Google Scholar, ScienceDirect, and PubMed (2014–2024). From 70 initially identified articles, 6 were selected using the PICOS method, focusing on Moringa supplementation, malnourished children, and growth outcomes. Results: Highland Moringa contains higher vitamin C and flavonoid levels, while lowland Moringa offers greater biomass for large-scale production. Studies confirm that dried Moringa extract significantly improves weight gain (p = 0.002), though its effects on height and inflammation reduction were less pronounced. Conclusion: Dried Moringa extract shows promise for weight gain and nutrition enhancement in stunted children. However, geographical factors influence its nutrient content, requiring further research to standardize formulations, optimize dosages, and assess long-term effects in human trials.
HUBUNGAN STATUS GIZI IBU HAMIL ANEMIA DENGAN PERTUMBUHAN FEMUR LENGHT JANIN Aquarista, Nita; Sulianty, Ati
Jurnal Midwifery Update (MU) Vol. 5 No. 2 (2023): Jurnal Midwifery Update (MU)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jmu.v5i2.175

Abstract

Latar Belakang : Angka stunting yang tinggi di Lombok Barat (24.4%) tahun 2017 menempati peringkat pertama di NTB.  Salah satu penyebabnya adalah status gizi kurang sebelum hamil dan anemia. Status gizi dapat ditentukan dengan IMT pra-hamil. Kurangnya status gizi berkaitan dengan kejadian anemia. Keduanya dapat menghambat pertumbuhan janin khususnya pertumbuhan femur length.  Tujuan : Untuk mengetahui hubungan status gizi ibu dengan pertumbuhan femur length janin pada ibu hamil anemia. Metode : Penelitian ini menggunakan Observational Analitik (Non-Eksperimental) dan pendekatan Cross Sectional dengan populasi seluruh ibu hamil anemia di wilayah kerja UPT BLUD Puskesmas Meninting, usia kehamilan awal 21-27 minggu. Sampel yang digunakan sebanyak 30 orang menggunakan teknik Purposive Sampling. Penelitian ini dilakukan dengan memantau hasil USG setiap bulan sebanyak 3 kali di dokter spesialis kandungan yang sama. Uji statistik yang digunakan dalam penelitian ini adalah Fisher Exact. Hasil: Status gizi sampel ibu hamil anemia paling banyak berada pada kategori kurus dengan IMT ≤ 18.5 sebanyak 19 orang (63%). Paling banyak pertumbuhan femur length janin mengalami ketidaksesuaian yaitu 25 orang (83.3%) dan 5 orang (16.7%) mengalami pertumbuhan sesuai. Hasil uji dengan Fisher Exact menunjukan p-value 0.047 (p < 0.05).  Kesimpulan : Terdapat Hubungan Antara Status Gizi Ibu dengan Pertumbuhan Femur Length Janin pada Ibu Hamil Anemia. AbstractBackground : High stunting rates in West Lombok (24.4%) in 2017 ranked first in NTB. One of the causes is poor nutritional status before pregnancy and anemia. Nutritional status can be determined by pre-pregnancy BMI. Lack of nutritional status is related to the incidence of anemia. These problems can inhibit fetal growth, especially femur length. Aim : To determine the correlation of maternal nutritional status with growth of fetal femur length in anemic pregnant women. Method : This study used Observational Analysis (Non-Experimental) and Cross Sectional approach with population of all anemic pregnant women in the working area of Meninting Health Care Center with initial gestational age of 21-27 weeks. The sample used was 30 samples using purposive sampling technique. This study was conducted by monitoring the results of ultrasound examination every month for 3 times at the same obstetrician. The test used in this study was Fisher Exact test. Results : The nutritional status of anemic pregnant women mostly in the thin category with BMI ≤ 18.5 as much as 19 people (63%). Mostly fetal femur length growth is unsuitable that is 25 people (83.3%) and 5 people (16.7%) experience suitable growth. Results of the test using Fisher Exact show p-value 0.025 (p <0.05). Conclusion : There is a Correlation Between Maternal Nutritional Status and Growth of Fetal Femur Length in Anemic Pregnant Women.
Development and Optimization of an Ultrasound-Assisted Extraction Apparatus with Integrated Advanced Features for Enhanced Essential Oil Production Fatmasari, Diyah; Widyawati, Melyana Nurul; Amartha, Tecky Afifah Santy; Fathonah, Yayuk; Aquarista, Nita; Amalia, Dhanty Nurul
Indonesian Journal of Electronics, Electromedical Engineering, and Medical Informatics Vol. 7 No. 1 (2025): February
Publisher : Jurusan Teknik Elektromedik, Politeknik Kesehatan Kemenkes Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/11vb2734

Abstract

The development of essential oil extraction techniques has seen significant advancements with the introduction of Ultrasound-Assisted Extraction (UAE) technology. UAE is known for its ability to accelerate chemical processes and improve the efficiency of essential oil extraction. However, to achieve optimal extraction quality and yield, precise control over various process parameters is required. This study focuses on enhancing the UAE extraction process by integrating modified features, including a temperature sensor, speed sensor, frequency regulator, temperature controller, stirrer, and cooler, into the extraction apparatus. Objective of this research is to develop a UAE-based extraction apparatus with advanced features that optimize the pre-treatment extraction process of essential oils. The research employs a Research and Development (R&D) approach to design and develop the UAE-based extraction apparatus. The apparatus is then tested to evaluate its performance in optimizing the extraction process. Experimental trials are conducted to assess the impact of each feature on the efficiency and quality of the extracted essential oils. The integration of the temperature sensor, speed sensor, frequency regulator, temperature controller, stirrer, and cooler allowed for better control over the extraction conditions, leading to higher yield and improved quality of the essential oils. The apparatus demonstrated its ability to consistently produce essential oils with higher purity and active ingredient concentrations compared to conventional methods. In conclusion, the development of the modified UAE-based extraction apparatus proves to be an effective solution for optimizing the essential oil extraction process