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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Inovasi Pendidikan dan Sains
Sipahutar, Nathalia E.R.
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Materials Science & Nanotechnology Mathematics Physics Social Sciences

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Routine Hematology Findings in Pulmonary Tuberculosis Cases at Regional General Hospital of Dr. Pirngadi, Medan, Indonesia Sihombing, Jenny Ria; Sipahutar, Gabriella M.C.; Sipahutar, Nathalia E.R.; Simanjuntak, Rotua Chatarina; Suhartomi
Jurnal Penelitian Pendidikan IPA Vol 11 No 2 (2025): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i2.10370

Abstract

Pulmonary Tuberculosis (TB) is an infection of the lung parenchyma caused by Mycobacterium tuberculosis and is transmitted via droplets. A routine hematological examination is crucial for evaluating disease progression, complications, and therapeutic responses. Thus, this study aimed to To identify routine hematological characteristics in pulmonary tuberculosis patients in RSUD Dr. Pirngadi Kota Medan. This observational study with cross-sectional design included 105 pulmonary tuberculosis patients, that selected via total sampling technique from 2019 to 2020. Data on demographic characteristics (age, sex, and occupation) and hematological profiles were analyzed. The majority of patients were male (67.6%), aged 46–55 years (24.8%), and worked as self-employed (47.6%). Hematological profiles showed elevated neutrophils (72.4%) and erythrocyte sedimentation rate (53.3%), alongside reduced hemoglobin (58.1%), hematocrit (61%), and lymphocytes (83.8%). Most patients had normal number of leukocytes (52.4%), platelets (63.8%), monocytes (47.6%), eosinophils (87.6%), and basophils (99%). he most characteristic routine hematological changes in pulmonary tuberculosis patients include decreased hemoglobin, hematocrit, and lymphocytes, as well as increased neutrophils and erythrocyte sedimentation rate. These findings emphasize the importance of hematological examination in the diagnosis and monitoring of pulmonary tuberculosis.
Unveiling Inflammation: Blood Peripheral Indices in Pulmonary Tuberculosis Sipahutar, Gabriella M.C.; Sihombing, Jenny Ria; Jirwanto, Hendra; Sipahutar, Nathalia E.R.; Suhartomi, Suhartomi; Sitepu, Sadarita
JURNAL INOVASI PENDIDIKAN DAN SAINS Vol 6 No 3 (2025): December
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Nahdlatul Wathan Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51673/jips.v6i3.2776

Abstract

Pulmonary tuberculosis (TB) remains a global and national health challenge. Peripheral blood inflammatory indices—NLR, PLR, PNR, MLR, dNLR, SIRI, SII, and AISI—have been proposed as markers of systemic inflammation and prognosis, yet local data are scarce and findings vary. Thus, this study was aimed to describe these indices in pulmonary TB patients at Dr. Pirngadi Regional General Hospital, Medan (2019–2020). This cross-sectional study was analysed 105 inpatient medical record via total sampling technique. Demographics and eight inflammatory indices were analyzed using descriptive statistics. Median values ​​of NLR, PLR, PNR, MLR, dNLR, SIRI, SII, and AISI in pulmonary tuberculosis patients are quite varied and tend to be higher than several previous studies. High NLR and PLR values ​​can reflect a severe degree of inflammation, while PNR and dNLR values ​​show less consistent results. Indices such as SIRI, SII, and AISI show potential as indicators of systemic inflammation, but still require further study. These indices have the potential to be used as markers of inflammation and prognosis in pulmonary tuberculosis, but cannot yet be used as a single reference
Co-Authors Jenny Ria Sihombing Jirwanto, Hendra Simanjuntak, Rotua Chatarina Sipahutar, Gabriella M.C. Sitepu, Sadarita Suhartomi SUHARTOMI .