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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Kedokteran Meditek
Suhartomi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health

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Case Report: Aspiration Pneumonitis as a Rare Complication Following Hydrogen Peroxide Intoxication Putri, Maulinda; Suhartomi; OK Yulizal; Syarifah, Siti
Jurnal Kedokteran Meditek Vol 31 No 4 (2025): JULI
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i4.3404

Abstract

Introduction: Suicide rates continue to rise globally, with self-poisoning being a common method in some developing countries. This report reported a case of hydrogen peroxide ingestion leading to aspiration pneumonitis, a less-discussed complication compared to gastrointestinal toxicity. Case Illustration: A 41-year-old woman presented to the emergency unit 8 hours post-ingestion of a hydrogen peroxide-based toilet cleaner. Symptoms included vomiting, hoarseness, faintness, and frothing at the mouth. The physical examination revealed dyspnea, irritability, a cleaning solution odor in the oral cavity, rhonchi in the middle and lower lung fields, epigastric tenderness, and increased bowel sounds. Gastric lavage with 200 mL of saline was performed, and activated charcoal and sucralfate syrup were administered via a nasogastric tube. The patient had previously received ranitidine at another facility and was also treated with omeprazole and ondansetron. Laboratory results showed leukocytosis, and a chest x-ray indicated bilateral lung infiltration and increased broncho-vascular pattern. Discussion: Early and proper intervention by trained healthcare professionals, combined with preventive measures such as positioning the patient in a semi-upright position and avoiding emetogenic liquids, is essential. Conclusion: This case showed the importance of prompt management involving gastric lavage, mucosal protection, acid suppression, and absorption inhibition. Nonetheless, respiratory complications, such as aspiration pneumonitis, remain challenging to prevent.
Routine Hematology Findings in Pulmonary Tuberculosis Cases at Regional General Hospital of Dr. Pirngadi, Medan, Indonesia Sihombing, Jenny Ria; Sipahutar, Gabriella M.C.; Sipahutar, Nathalia E.R.; Simanjuntak, Rotua Chatarina; Suhartomi
Jurnal Penelitian Pendidikan IPA Vol 11 No 2 (2025): February
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i2.10370

Abstract

Pulmonary Tuberculosis (TB) is an infection of the lung parenchyma caused by Mycobacterium tuberculosis and is transmitted via droplets. A routine hematological examination is crucial for evaluating disease progression, complications, and therapeutic responses. Thus, this study aimed to To identify routine hematological characteristics in pulmonary tuberculosis patients in RSUD Dr. Pirngadi Kota Medan. This observational study with cross-sectional design included 105 pulmonary tuberculosis patients, that selected via total sampling technique from 2019 to 2020. Data on demographic characteristics (age, sex, and occupation) and hematological profiles were analyzed. The majority of patients were male (67.6%), aged 46–55 years (24.8%), and worked as self-employed (47.6%). Hematological profiles showed elevated neutrophils (72.4%) and erythrocyte sedimentation rate (53.3%), alongside reduced hemoglobin (58.1%), hematocrit (61%), and lymphocytes (83.8%). Most patients had normal number of leukocytes (52.4%), platelets (63.8%), monocytes (47.6%), eosinophils (87.6%), and basophils (99%). he most characteristic routine hematological changes in pulmonary tuberculosis patients include decreased hemoglobin, hematocrit, and lymphocytes, as well as increased neutrophils and erythrocyte sedimentation rate. These findings emphasize the importance of hematological examination in the diagnosis and monitoring of pulmonary tuberculosis.
Effect of Pakkat Ethanol Extract (Calamus L. Blum) on Spermatogenesis and Testosterone Levels of Diabetes Mellitus Wistar Rats Lubis, Yolanda Eliza Putri; Aipin, Anggi Sri Ananda; Hanjaya; Lina, Juliana; Suhartomi
Jurnal Penelitian Pendidikan IPA Vol 11 No 12 (2025): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i12.13495

Abstract

Diabetes mellitus is a metabolic disorder marked by high blood glucose levels (hyperglycemia) that is caused by insulin deficiency. It also affects male infertility. Pakkat, young rattan, contains various phytochemicals, which can affect blood glucose levels, spermatogenesis, and testosterone production. Objective: To assess the effectiveness of Pakkat extract in regulating blood glucose levels, testosterone hormone, and spermatogenesis in alloxan-induced diabetic rats. This experimental study used 25 diabetic male Wistar rats and was grouped into five groups including negative control (distilled water), positive control (metformin), Treatment 1 (125 mg/KgBW Pakkat extract), 2 (250 mg/KgBW Pakkat extract), and 3 (500 mg/KgBW Pakkat extract) for 14 days. All data were analyzed by One-way ANOVA followed by a Post-Hoc Test. Pakkat extract at 125 mg/kgBW dose effectively reduced glucose levels (P-Value < 0.001) after 14 days. It also significantly increased spermatogenesis (P-Value < 0.001) and testosterone levels (P-Value < 0.001) in alloxan-induced diabetic rats. Thus, it can be concluded that any doses of Pakkat (Calamus L. Blume) extract significantly improve blood glucose levels after 14 days of administration. However, a higher dosage is required to increase spermatogenesis and testosterone hormone in diabetic conditions.
Co-Authors Aipin, Anggi Sri Ananda Hanjaya Jenny Ria Sihombing Lina, Juliana Putri, Maulinda Simanjuntak, Rotua Chatarina Sipahutar, Gabriella M.C. Sipahutar, Nathalia E.R. Syarifah, Siti Yolanda Eliza Putri Lubis Yulizal, Ok