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Telemedicine and AI in Occupational Skin Disease Management: A Contemporary Review Purwoko, Reza Yuridian; Muliadi, Jemie; Roestam, Rusdianto; Wan Sen, Tjong Wan Sen; Pamungkas, Lukas Sangka; Nugroho, Anto Satriyo; Armi, Nasrullah; Supriyadi, Muhamad Rodhi; Melati, Rima; Alfaqih, Muhammad Subhan; Montolalu, Ivan Adrian; Ruhdiat, Rudi; Ferianasari, Inneke Winda; Aryanti, Evy Aryanti; Saputra, Silvan; Asmail, Asmail; Rahayaan, Manuela; Hi Rauf, Siti Nuraini
FIRM Journal of Management Studies Vol 8, No 2 (2023): FIRM JOURNAL OF MANAGEMENT STUDIES
Publisher : President University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33021/firm.v8i2.5802

Abstract

Occupational skin diseases present significant challenges to workplace health, impacting both productivity and quality of life. The integration of telemedicine and artificial intelligence (AI) has transformed dermatological care by facilitating remote consultations, enabling early diagnosis, and supporting continuous monitoring. The COVID-19 pandemic has accelerated the adoption of digital health solutions, underscoring their potential to enhance accessibility and efficiency in occupational dermatology.AI-driven innovations, including machine learning algorithms and wearable technologies, have further improved diagnostic accuracy and patient management. However, challenges such as healthcare disparities, technological limitations, and workplace-specific factors continue to hinder widespread implementation. This review explores the evolving role of telemedicine and AI in managing occupational skin diseases, highlighting key challenges, emerging opportunities, and policy considerations for enhancing workplace health outcomes.
Stem Cell-based Therapeutic Approaches For Thalassemia: A Systematic Review Rahayaan, Manuela; Hi Rauf, Siti Nuraini; Meralda, Arla Sindu
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Book of Abstrack RCIMS 2025
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.vi.965

Abstract

Thalassemia is a hereditary hematologic disorder characterized by defective hemoglobin synthesis, resulting in chronic anemia and rekated systemic complications, which are often managed through lifelong blood transfusions and iron chelation therapies. Recent advances in cell-based therapeutic strategies, particularly hematopoietic stem cell ( HCS ) gene therapy, have demonstrated substantial potential in addressing the underlying genetic defects and improving erythropoiesis. This systematic review evaluates preclinical and clinical studies, from PubMed, ScienceDirect, SCOPUS, focusing on the efficacy of HSC gene therapy and other immunomodulatory cellular approaches in thalassemia models. Studies involving thalassemic mice indicated that HCS-based gene therapy significantly enhanced ?-globin expression and restored normal red blood cell phenotypes, suggesting functional hematologic improvements. Complementary strategies involving regulatory T cells (Tregs) and engineered immune cells, including CAR-T and NK cells, offer additional promise for immune modulation, transplant tolerance, and the reduction of therapy-related complications. Despite these advances, challenges including limited cell availability, complex ex vivo culture conditions, immune rejection, and scalability remain. Innovations in genome editing, engineered TCR/CAR technology and CRISPR/Cas-edited iPSC-derived cells may further improve specificity, stability, and efficacy. Collectively, cell-based therapies offer a transformative approach for thalassemia by correcting the underlying genetic defect and modulating immune responses, with the potential to reduce dependence on conventional transfusions and enhance quality of life. Further clinical studies are required to establish long-term safety, feasibility and therapeutic efficiency in human patients