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A Case Report: Multidrug-Resistant Tuberculosis in A 53-Year-Old Patient Mustofa, Syazili; Ananta, Yoga; Ginting, Bisart; Septiani, Linda; Busman, Hendri
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 2 (2025): Volume 12 Nomor 2
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i2.18173

Abstract

A 53-year-old man with multidrug-resistant tuberculosis (MDR-TB) presented with clinical symptoms such as cough with yellow-white sputum for a month, shortness of breath, fever, night sweats, and weight loss. After completing six months of TB treatment in 2010, he developed MDR-TB, proven by resistance to rifampicin. Initial diagnosis by chest X-ray showed signs of pulmonary TB and right pleural effusion, while the sputum test confirmed Mycobacterium tuberculosis with moderate bacterial load. Laboratory results showed anemia, leukocytosis, and hypoalbuminemia. The patient's therapy included a combination of bedaquiline, levofloxacin, linezolid, clofazimine, cycloserine, and vitamin B6, along with additional treatments such as antibiotics, symptomatic therapy, and nutritional support. The medical team conducted regular monitoring and consultation with pulmonary, psychiatry, and nutrition specialists to ensure treatment compliance. This case highlights the challenges in managing MDR-TB, especially in patients with a history of TB. Early detection of drug resistance and prompt implementation of appropriate therapy are essential to improve treatment outcomes and prevent further spread. This report emphasizes the need for a multidisciplinary approach and close monitoring in the management of MDR-TB.
INFEKSI SALURAN KEMIH AKIBAT PENGGUNAAN KATETER PADA PASIEN RAWAT INAP DI RUMAH SAKIT Ananta, Yoga; Mustofa, Syazili; Septiani, Linda; Busman, Hendri
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1436

Abstract

Urinary tract infection (UTI) is a disorder caused by microorganisms that multiply in the urinary tract, which is normally sterile from bacteria. Risk factors for UTI include age, gender, medical procedures such as catheterization, hygiene, and duration of catheter use. Catheter-related UTI is the most common type of nosocomial infection, with a prevalence of up to 80% in patients who use catheters. The main cause of UTI is gram-negative bacteria, such as Escherichia coli (48.44%) and Klebsiella pneumoniae. In women, the risk is higher because the urethra is shorter and closer to the anus. UTI is divided into lower and upper urinary tract infections, where symptoms vary from pain during urination to serious complications such as pyelonephritis and urosepsis. The pathophysiology of UTI often involves the colonization of microorganisms on the catheter or urinary tract. The risk of infection increases with the duration of catheter placement, reaching 5–10% per day. Diagnosis of UTI involves history taking, physical examination, and urine culture, although modern methods such as flow cytometry are increasingly used for efficiency. Prevention involves personal hygiene, aseptic technique during catheter insertion, and prophylactic antibiotic use in selected cases. Treatment of UTI includes empiric antibiotics such as trimethoprim-sulfamethoxazole, fluoroquinolones, or nitrofurantoin, depending on the severity and causal pathogen. Appropriate preventive and treatment approaches can reduce the incidence of UTI, improve patient quality of life, and decrease the rate of complications. Keywords: Trigger Factors, Urinary Tract Infection (UTI), Catheter
ANALISIS PEMANFAATAN DAN PEMELIHARAAN TERHADAP MANAJEMEN SARANA DAN PRASARANA PENDIDIKAN Sucia, A. Zahra Intan; Prihatmi, Erina; Ananta, Yoga; Supriyadi, Supriyadi; Izzatika, Amrina
JGK (Jurnal Guru Kita) Vol. 9 No. 1: Desember 2024
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jgk.v9i1.64392

Abstract

Pendidikan masa kini penting dalam memanajemen sarana prasarana guna mendorong meningkatnya kualitas pembelajaran. Kualitas pendidikan dan sarana prasarana sebagai penunjang mempunyai korelasi yang erat. Penelitian ini bertujuan guna mengetahui pengaruh pemanfaatan dan pemeliharaan terhadap sarana dan prasarana pendidikan agar menjadi opimal. Pendekatan kualitatif dengan jenis deskriptif, yaitu telaah pustaka memakai berbagai sumber literatur dan artikel sebagai bahan analisis dari penelitian dipakai sebagai metode dalam penelitian ini. Berdasarkan penelitian dan pembahasan disimpulkan: Tingkat pemanfaatan sarana dan prasarana sekolah merupakan indikator pengukuran baik-buruknya pelayanan yang diberikan sekolah kepada pelanggannya. Sesuai dengan Undang-Undang RI No. 20 Tahun 2003 tentang Sistem Pendidikan Nasional, Bab XII, Pasal 45, analisis pemanfaatan sarana dan prasarana guna menunjang aktivitas pendidikan memperlihatkan bahwa tingkat pemanfaatan sarana dan prasarana sekolah memperlihatkan seberapa baik pelayanan yang diberikan sekolah kepada pelanggannya. Pemeliharaan sarana dan prasarana pendidikan biasanya dibagi menjadi dua kategori: barang tidak bergerak yang diperiksa dan barang bergerak yang diperiksa berdasarkan sifat dan waktunya karena sarana pendidikan sangat penting untuk dipakai dan dipelihara dengan baik, kepala sekolah harus selalu berkomunikasi dengan pengelola sarana dan prasarana, guru, dan warga sekolah yang ikut serta. Jika siswa memakai dan mempertahankan sumber belajar yang ideal, maka akan memicu motivasi untuk belajar.