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All Journal Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry
Swe, Thet Thet
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Odontogenic maxillary sinusitis and oroantral communication: A case report Dipankara, Jackson; Hadrian, Gary; Eddy; Putri, Tansza Setiana; Rinanti, Astri; Swe, Thet Thet; Poedjiastoeti, Wiwiek
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 2 (2025): June
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i2.p194-197

Abstract

Background: Odontogenic maxillary sinusitis (OMS) and oroantral communication (OAC) have been well recognized in oral and maxillofacial surgery. The treatment ranges from non-surgical treatment to surgical treatment. Purpose: This case report discusses the management of OMS and OAC through a non-surgical approach. Case: A female patient presented to our department after being referred from a different department. After informed consent was obtained, her tooth was extracted. Unfortunately, the maxillary sinus was exposed, and OMS was suspected after pus leakage occurred into the oral cavity prior to tooth extraction. The communication was found at the mesiobuccal region with a 3 mm diameter and distobuccal region with a 2 mm diameter. Case management: Due to the small size of the OAC, it was decided to close the communication using the figure-of-eight suture technique, and an absorbable gelatin sponge was placed inside the socket. Odontogenic maxillary sinusitis was treated with a combination of pharmacological therapy and dental therapy, including the removal of the source of infection and a prescription of antibiotics and nasal decongestant due to the OAC. Finally, the patient was educated about the sinus precaution step. Conclusion: Good healing of the lesion was noted in this report. Non-surgical treatment such as dental therapy and pharmacological therapy can, therefore, be considered to treat OMS. Closure of the OAC using a suture technique and a gelatin sponge can treat small-sized communication.
Cytotoxicity of β-tricalcium phosphate chitosan gelatin composite scaffold as a bone substitute: in vitro study Putri, Tansza Setiana; Eddy, Eddy; Pratiwi, Deviyanti; Kurniawan, Florencia Livia; Swe, Thet Thet
Padjadjaran Journal of Dentistry Vol 38, No 1 (2026): March 2026
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol38no1.63795

Abstract

Introduction: Beta-tricalcium phosphate (βTCP) has higher solubility than hydroxyapatite (HA), allowing it to be more easily resorbed and replaced by newly formed bone. This higher solubility enables the release of calcium and phosphate ions that play important roles in bone remodeling and osteoblast activity; however, excessive ion release may lead to cytotoxic effects. Limestone, mainly composed of calcium carbonate (CaCO₃), can serve as a calcium source for the fabrication of βTCP. βTCP scaffolds can be combined with organic components such as chitosan and gelatin to form composite scaffolds for bone tissue engineering. Therefore, this study aimed to analyze the cytotoxicity of a β-tricalcium phosphate–chitosan–gelatin composite scaffold as a bone substitute. Methods: Type of research was experimental laboratory. Freeze-drying method was used to produce a composite scaffold which was divided into two groups: chitosan-gelatin scaffold as control group and βTCP-chitosan-gelatin scaffold (each group consisted of three samples) To evaluate cytotoxicity, composite scaffolds were tested on osteoblast cells and the MTT assay was measured and assessed based on time evaluation at 24 hours and 72 hours. Cytotoxicity was determined based on the percentage of viable cells obtained from the MTT assay. Results: Viable cells percentage on the chitosan-gelatin scaffold was 70.32% at 24 h and increased to 99.52% at 72 h. While on the chitosan-gelatin-βTCP scaffold there were 85.11% viable cells at 24 h and increased to 89.54% at 72 h. Statistical analysis using one-way ANOVA showed no significant difference among all groups (p>0.05). However, Fisher’s LSD test indicated a significant difference in cell viability between 24 hours and 72 hours within the chitosan gelatin group. Conclusion: The βTCP-chitosan-gelatin composite scaffold demonstrated no cytotoxic effect on osteoblast cells, indicating its biocompatibility and potential suitability as a bone substitute material.
Co-Authors Deviyanti Pratiwi Dipankara, Jackson Eddy Eddy Eddy, Eddy Florencia Livia Kurniawan Hadrian, Gary Tansza Setiana Putri Wiwiek Poedjiastoeti, Wiwiek