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Daya Analgesik Ekstrak Daun Picisan (Polypodium nummulariifolium Mett) Pada Mencit Putih Ceriana, Ria; Mukhlisa, Ida; Zafis, Fathiya Imaniyyah; Safira, Ulfia; Pratiwi, Silvia Putri; Desi, Navira Nava; Husni, Barada; Rumaida, Rumaida; Kinanti, Kinanti; Adisah, Nur; Putri, Virda
Science: Indonesian Journal of Science Vol. 1 No. 2 (2024)
Publisher : LPPI Yayasan Almahmudi bin Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/science.v1i2.15

Abstract

Pengalaman empirik tentang pemanfaatan aneka herba dalam seni pengobatan dunia timur telah menarik perhatian masyarakat barat untuk mempelajari lebih lanjut tanaman herba sebagai sumber obat- obatan masa depan. Daun picisan termasuk dalam famili Polypodiaceae. Daun picisan memiliki berbagai manfaat diantaranya dapat digunakan sebagai antinyeri atau analgesik. Penelitian ini menggunakan sampel dan konsentrasi yang berbeda dari penelitian sebelumnya dimana sampel diambil berasal dari daerah Aceh Besar dengan volume 0,5 ml. Oleh karena itu, penelitian ini perlu dilakukan untuk mengetahui daya analgesik ekstrak daun picisan (Polypodium nummulariifolium Mett) pada mencit putih. Penelitian ini menggunakan 3 kelompok perlakuan yaitu akuades, ekstrak daun picisan dan obat Ibuprofen. Perlakuan tersebut diulang sebanyak 3 kali. Data dianalisis secara deskriptif yang ditampilkan dalam bentuk tabel. Kesimpulan dari penelitian ini adalah ekstrak daun picisan memiliki daya analgesik yang dapat terlihat dari penurunan jumlah lompatan pada mencit.
Formulasi Sediaan Body Scrub Pencerah Kulit Dari Serbuk Kopi Robusta (Coffea Robusta L) dan Lidah Buaya (Aloe Vera) Lidyawati, Lidyawati; Mardiana, Rosa; Pratiwi, Silvia Putri
Journal of Pharmaceutical and Health Research Vol 6 No 1 (2025): February 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i1.6220

Abstract

Body scrub is one form of pharmaceutical preparation that functions to clean the skin from dirt, dead skin cells, dust, and oil with the help of scrub particles that act as abrasives. Currently, the use of natural body scrubs is more popular because of the minimal risks and side effects. Robusta coffee beans and aloe vera extract contain flavonoid compounds that function as free radical scavengers. This study aims to determine whether robusta coffee beans (Coffea Robusta) and aloe vera extract (Aloe vera) can be used as a body scrub preparation to ward off free radicals, and to evaluate their physical stability through organoleptic testing, pH testing, homogeneity, accompanied by irritation testing. This study used an experimental method in the laboratory. The body scrub formulation was developed in three variations of the proportion of coffee extract and powder, namely F0 (0%), F1 (4.6%), and F2 (6.13%). Evaluation of the body scrub preparation includes organoleptic testing, homogeneity testing, pH testing, and skin irritation testing. The results showed that robusta coffee beans and aloe vera extract can be formulated into a body scrub preparation. The results of the pH test show that the pH of the body scrub is 6, according to the pH of the skin, so it is safe when applied to the skin. The results of the volunteer skin irritation test are also safe, having no irritating effect on the skin.