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All Journal Journal of Pharmaceutical and Health Research Aceh Sanitation Journal (ASjo) Journal of Health Science and Medical Therapy Science: Indonesian Journal of Science Jurnal Sains & Kesehatan Darussalam
Mukhlisa, Ida
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Physics Public Health

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Effectiveness of Chinese Betel Leaf Extract (Peperomia pellucida L) on the Growth of Propionibacterium acnes Bacteria Mukhlisa, Ida; Juwita ZR, Juwita ZR; Dita, Sasmiati Farach
Journal of Health Science and Medical Therapy Том 3 № 01 (2025): Journal of Health Science and Medical Therapy
Publisher : PT. Riset Press International

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59653/jhsmt.v3i01.1435

Abstract

Propionibacterium acnes bacteria cause acne by producing lipase enzymes that break down free fatty acids in skin lipids. This study aimed to determine whether or not there is antibacterial activity from the extract of the Chinese betel leaf plant (Peperomia pellucida L) against Propionibacterium acnes and to determine the concentration of the inhibition zone. The study was experimental with 25%, 50%, 75% and 100% extract concentrations. The method used to test antibacterial activity in this study was the disc diffusion method, namely using discs planted on Nutrient Agar (NA) media. The maceration of Chinese betel leaves (Peperomia pellucida L) is the Chinese betel leaf extraction method. The results showed that at a concentration of 25% Chinese betel leaf extract, the results were 22.5 mm; at a concentration of 50% extract, the inhibition zone was 24 mm; at a concentration of 75% Chinese betel leaf extract, the inhibition zone was 30 mm, at a concentration of 100% Chinese betel leaf extract, the inhibition zone was 20 mm. The inhibition zone of the positive control using the antibiotic chloramphenicol was obtained at 10 mm; in the negative control using sterile distilled water, there was no inhibition zone. The results of the significance test of the Chinese betel leaf extract (Peperomia pellucida) from the Greenwood classification results in the Post hoc test show that the difference between concentrations can be stated as significant at each concentration.
Formulasi Sabun Mandi Padat Transparan Dari Ekstrak Bunga Kamboja Putih (Plumeria alba L.) Adriani, Azmalina; Mardiana, Rosa; Mukhlisa, Ida; Wahyuna, Nadira Dina; Khairunnisa
Journal of Science and Health Darussalam Vol. 4 No. 2 (2024): Jurnal Sains dan Kesehatan Darussalam
Publisher : Akademi Analis Farmasi dan Makanan Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56690/jskd.v4i2.153

Abstract

Sabun mandi dengan zat aktif ekstrak bunga kamboja putih (Plumeria alba L) dapat digunakan sebagai zat aktif dalam pembuatan sabun. Tujuan dari penelitian ini adalah untuk menformulasikan sabun mandi padat transparan dari ekstrak bunga kamboja putih yang berfungsi untuk membersihkan tubuh dari kontaminasi bakteri, debu dan kotoran lainnya dan dapat melembabkan kulit. Penelitian ini merupakan penelitian yang bersifat eksperimental dengan membuat 4 tipe sediaan sabun padat. Yang membedakan yaitu dasar sabun (Kontrol Negatif), sabun padat yang diformulasikan dengan ekstrak bunga kamboja putih pada konsentrasi 1,%, 3% dan 4,5%. Hasil penelitian menunjukkan bahwa ekstrak bunga kamboja putih dapat diformulasikan dalam bentuk sediaan sabun mandi padat transparan. Konsentrasi ekstrak bunga kamboja yang paling bagus dalam formulasi sediaan sabun mandi padat transparant adalah konsentrasi 4,5%, hal ini dibuktikan pada konsentrasi 4,5% sediaan sabun mandi padat transparant tetap stabil dan tidak tejadi perubahan warna, bau, bentuk dan pH dan tinggi busa yang stabil. Kata kunci: Bunga Kamboja Putih, Sabun Mandi Padat Transparant
Daya Analgesik Ekstrak Daun Picisan (Polypodium nummulariifolium Mett) Pada Mencit Putih Ceriana, Ria; Mukhlisa, Ida; Zafis, Fathiya Imaniyyah; Safira, Ulfia; Pratiwi, Silvia Putri; Desi, Navira Nava; Husni, Barada; Rumaida, Rumaida; Kinanti, Kinanti; Adisah, Nur; Putri, Virda
Science: Indonesian Journal of Science Vol. 1 No. 2 (2024)
Publisher : LPPI Yayasan Almahmudi bin Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/science.v1i2.15

Abstract

Pengalaman empirik tentang pemanfaatan aneka herba dalam seni pengobatan dunia timur telah menarik perhatian masyarakat barat untuk mempelajari lebih lanjut tanaman herba sebagai sumber obat- obatan masa depan. Daun picisan termasuk dalam famili Polypodiaceae. Daun picisan memiliki berbagai manfaat diantaranya dapat digunakan sebagai antinyeri atau analgesik. Penelitian ini menggunakan sampel dan konsentrasi yang berbeda dari penelitian sebelumnya dimana sampel diambil berasal dari daerah Aceh Besar dengan volume 0,5 ml. Oleh karena itu, penelitian ini perlu dilakukan untuk mengetahui daya analgesik ekstrak daun picisan (Polypodium nummulariifolium Mett) pada mencit putih. Penelitian ini menggunakan 3 kelompok perlakuan yaitu akuades, ekstrak daun picisan dan obat Ibuprofen. Perlakuan tersebut diulang sebanyak 3 kali. Data dianalisis secara deskriptif yang ditampilkan dalam bentuk tabel. Kesimpulan dari penelitian ini adalah ekstrak daun picisan memiliki daya analgesik yang dapat terlihat dari penurunan jumlah lompatan pada mencit.
The Relationship Between Frequency And Breastfeeding Education With The Smoothness Of Postpartum Mother's Breast Milk Production In The Matang Janeng Village Community Aiman, Ummu; Mukhlisa, Ida
Aceh Sanitation Journal Vol 2 No 2 (2023): ,
Publisher : Jurusan Kesehatan Lingkungan, Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The World Health Organization (WHO), United Nation International Children's Emergency fund (UNICEF) and the Ministry of Health recommend initiating breastfeeding within the first hour of a baby's life, exclusive breastfeeding for 6 months, up to 2 years, breastfeeding must be provided together with a safe breastfeeding companion. and nutritious. Production of breastmilk that is not smooth is one of the factors that causes failure in exclusive breastfeeding. One of the efforts to increase breast milk is by breastfeeding children regularly. The purpose of this study was to determine the relationship between the frequency of breastfeeding and the smooth production of postpartum mother's milk in Matang Janeng Village, Tanah Pasir District, North Aceh Regency. This type of research is analytic with cross sectional study design, with a sample of 38 people by total sampling. This research was conducted from 13 to 26 July 2020 with the method of measuring the distribution of questionnaires. Data processing was performed using the chi square test. The results of the univariate analysis showed that the frequency of breastfeeding in postpartum mothers was mostly in the irregular category amounting to 23 people (60.5%) and the milk production of postpartum mothers was mostly in the non-smooth category amounting to 21 people (55.3%) while the results of the analysis bivariate, it was found that there was a relationship between the frequency of breastfeeding and the smooth production of breast milk for postpartum mothers with a p value of 0.003. It is hoped that respondents can breastfeed their babies regularly so that milk production can come out smoothly so that the baby can be fulfilled with nutrition
Formulasi Sediaan Masker Peel off dari Ekstrak Buah Batok Aceh (Limonia Acidissima L.) Sebagai Pencerah Kulit Mukhlisa, Ida; Riska, Riska; Mardiana, Rosa; Yusrawati, Yusrawati
Journal of Pharmaceutical and Health Research Vol 6 No 3 (2025): October 2025
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v6i3.8385

Abstract

Batok fruit or known as Limonia acidissima is a fruit commonly found in South and Southeast Asia, with content that has the potential to provide benefits for skin health. Batok fruit contains many antioxidants that can improve skin brightness. This study aims to formulate and evaluate the physical characteristics of peel-off mask preparations to brighten the skin containing Aceh batok fruit extract (Limonia acidissima). The extract was obtained by maceration method using 96% ethanol solvent. The mask preparations were made in four formulations: F0 as a base without extract, and F1, F2, and F3 with extract concentrations of 10%, 20%, and 30%, respectively. Evaluation of the quality of the preparations included organoleptic tests, homogeneity, pH, viscosity, spreadability, adhesion, drying time, and irritation test. The results showed that the addition of the extract affected the color of the preparation from yellow to yellowish brown and gave the extract a distinctive aroma. All formulas were proven safe, with pH values ​​within the physiological range of the skin (6.2-6.4) and did not irritate the panelists' skin. The drying time for all formulas was uniform, at 15 minutes. Formula F3 (30% extract) demonstrated the best spreadability (4.5 cm) compared to the other formulas. However, all formulas showed inhomogeneous results and had adhesion below the ideal standard for topical preparations, which is less than 2 seconds. It was concluded that formula F3 was the most optimal among those tested because it had the best spreadability, did not cause irritation, and improved skin brightness after washing for 1 week. However, further research is needed to improve the homogeneity and adhesion of the formulations.
Co-Authors Adisah, Nur Adriani, Azmalina Aiman, Ummu Desi, Navira Nava DITA, SASMIATI FARACH Husni, Barada Juwita ZR, Juwita ZR Khairunnisa Kinanti Kinanti, Kinanti Mardiana, Rosa Pratiwi, Silvia Putri Putri, Virda Ria Ceriana, Ria Riska Riska Rumaida, Rumaida Safira, Ulfia Wahyuna, Nadira Dina Yusrawati Yusrawati Zafis, Fathiya Imaniyyah