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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Farmasi Indonesia JURNAL FARMASIMED (JFM) Jurnal Farmasi dan Sains Indonesia (JFSI) Generics: Journal of Research in Pharmacy Jurnal Pharmacopoeia SEMINAR NASIONAL PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT Generics : Journal of Research in Pharmacy Jurnal Sains dan Kesehatan JPEMAS: Jurnal Pengabdian Kepada Masyarakat
Purwaningsih, Avianti Eka Dewi Aditya
Program Studi Profesi Apoteker, Fakultas Farmasi, Universitas Setiabudi, Surakarta, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : JURNAL FARMASIMED (JFM)

 1 
Evaluation of Inpatient Antibiotic Use at Hospital X, Semarang Regency, in 2023 Using Quantitative Methods Ivana; Avianti Eka Dewi Aditya Purwaningsih; Fadhila Shaumi Chunaesiana
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/q734wz44

Abstract

Background: Antibiotic resistance is a critical global health problem resulting from the inappropriate use of antibiotics. Understanding the pattern of antibiotic utilization is necessary to support rational prescribing and reduce resistance.Objective: This study aimed to evaluate the pattern of antibiotic use among inpatients at Hospital X in Semarang Regency in 2023. Methods: A retrospective study was conducted among inpatients aged 19–59 years who received antibiotic therapy between January and December 2023. Data were analyzed using the Anatomical Therapeutic Chemical/Defined Daily Dose method and Drug Utilization 90% to assess consumption patterns. Results: A total of 1,402 patients were included, with most patients being female and within the 49–59 age group. The majority of hospital stays lasted 1–5 days. Ceftriaxone injection is the most frequently used antibiotic and records the highest defined daily dose, followed by levofloxacin and ampicillin sulbactam. Conclusion: The study shows that ceftriaxone injection dominates antibiotic utilization. Regular evaluation using standardized methods is essential to ensure appropriate use and prevent resistance. Antibiotic procurement policies should be guided by actual consumption data to improve efficiency in drug management.
Antibiotic Use in Inpatients with Diarrhea in Children: A Quantitative Evaluation at Hospital X, Semarang Regency, 2023 Widiastuti, Zulfia; Purwaningsih, Avianti Eka Dewi Aditya; Ulum, Amalia Nurul
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/s8qfqn40

Abstract

Background : Infection remain one of the leading causes of morbidity in tropical regions such as Indonesia, with Escherichia coli being one of the most freequently identified pathogens. The high incidence of Escherichia coli-related infections has led to increased antibiotics use, considering that this commensal gut bactericum can cause both asymptomatic infections and symtomatic diarrhe, either bloody or non-bloody. Objective : This study aimed to evaluate use in pediatric patiens with diarrea at Hospital X, Semarang Regency, in 2023. Methods: This was a retrospective study uutilizing medical records of 323 pediatric patiens who met the inclusion and exclusion criteria. Data analysis was performed using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) methodology. Result:The analysis revealed that Ceftriaxone injection was the most frequently used antibiotic (61.95%), followed by Ampicillin, Amikacin, Gentamicin, and Cefotaxime. Ceftriaxone was often prefered due to its efficacy against both gram-positive and gram-negative bacteria comonly associated with pediatric diarrhea, as well as the advantage of accurate dosing trough injectable formulations. Most diarrhea cases occurred in boys (62.54%) and in children under five years of age (65.63%). Conclusion:Injectable formulations were chosen to reduce the risk of vomiting and to facilitate precise and effective dosing. Evaluation using the ATX/DDD method highlighted the need for more rational antibiotic management to prevent bacterial resistance in the future. Optimizing antibiotic stewardship is crucial to ensure targeted in the future. Optimizing antibiotic stewardship is crucial to ensure targeted, effective use and to preserve therapeutic efficacy in the long term. 
Co-Authors Abadi, Dzithauly Maulidiva Adhi Wardhana Amrullah Adhi Wardhana Amrullah Agnes Prawistya Sari Amrullah, Adhi Wardhana Atiek Murharyati Chandra, Sherley Widya Djoko Wahyono Djoko Wahyono Eersta Zusvita Widyastuti Effendy, Aura Nurul Alfiah Endang Sri Rejeki Fadhila Shaumi Chunaesiana Fita Rahmawati Fita Rahmawati Harsono, Samuel Budi Ivana Marlina, Dian Nur Anggreini Dwi Sasangka Rahardjoputro, Rolando Rolando Rahardjoputro Sari, Agnes Prawistya Ulum, Amalia Nurul Untsa, Farrohatul Widiastuti, Zulfia Widyaningrum, Riana Widyastuti, Eersta Zusvita