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All Journal BioEksakta : Jurnal Ilmiah Biologi Unsoed Jurnal Medika Veterinaria
Indriani, Amanda
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

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Keunikan Plestiastrea sp., Acropora Cervicornis, Pleuractis Paumotensis di perairan Laut Teluk Tamiang, Kalimantan Selatan Jumrodah, Jumrodah; Indriani, Amanda; Rosida, Anis; Najhah, Nor Rezqiyatun; Nuridah, Nuridah; Pitria, Pitria; Azizah, Sarah; Maysaroh, Siti; Alia, Rahmah
BioEksakta : Jurnal Ilmiah Biologi Unsoed Vol 7 No 2 (2025): BioEksakta
Publisher : Fakultas Biologi Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.bioe.2025.7.2.14498

Abstract

Penelitian ini bertujuan untuk mendeskripsikan morfologi tiga spesies yaitu Plestiastrea sp, Acropora cervicornis, dan Pleuractis paumotensis yang ditemukan di ekosistem terumbu karang Teluk Tamiang, Kabupaten Kotabaru, Kalimantan Selatan. Penelitian ini menggunakan metode deskriptif dengan observasi langsung melalui snorkeling, pengambilan dokumentasi foto bawah air, dan pengamatan mikroskopis terhadap sampel. Selain itu, dilakukan juga pengukuran parameter lingkungan seperti suhu, pH, salinitas, dan intensitas cahaya untuk mengetahui kondisi habitat. Hasil pengamatan menunjukkan bahwa ketiga spesies memiliki morfologi yang khas dan berpotensi sebagai bioindikator kesehatan ekosistem. Plestiastrea sp. memiliki koloni bulat dengan polip besar; Acropora cervicornis memiliki cabang menyerupai tanduk rusa; sedangkan Pleuractis paumotensis berbentuk cakram dengan septa radial. Penelitian ini memberikan informasi awal yang dapat mendukung kajian taksonomi dan pelestarian spesies lokal di wilayah pesisir Kalimantan Selatan Kata kunci : Ekosistem terumbu karang, Teluk Tamiang
Antihyperuricemic Effect of the Combination of Eleutherine bulbosa and Syzygium polyanthum Extracts on Uric Acid Reduction in Hyperuricemic Mice Indriani, Amanda; Hujjatusnaini, Noor; Nurindahsari, Lilin Ika
Jurnal Medika Veterinaria Vol 19, No 2 (2025): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v19i2.48281

Abstract

Hyperuricemia is a metabolic disorder characterized by elevated serum uric acid levels, which may lead to gout and other related complications. Long-term pharmacological treatments often cause adverse effects, making natural products a promising alternative therapy. This study aimed to evaluate the antihyperuricemic activity of a combined extract of Eleutherine bulbosa (Dayak onion) and Syzygium polyanthum (bay leaf) in hyperuricemic mice (Mus musculus). The experiment employed a post-test only control group design using 28 male Balb/c mice induced with a high-purine diet to establish hyperuricemia. Treatments included single and combined extracts of E. bulbosa and S. polyanthum at doses of 100, 200, and 300 mg/kg body weight with a ratio of 1:2, alongside a positive control (allopurinol). Phytochemical analysis revealed the presence of flavonoids, tannins, and saponins, which act as xanthine oxidase inhibitors and synergistic antioxidants. Statistical analysis using one-way ANOVA indicated a significant effect of the extract combination on reducing serum uric acid levels (p = 0.016). Further Duncans post-hoc test identified the 200 mg/kg dose (1:2 ratio) as the most effective, exhibiting a response comparable to allopurinol. These results suggest that the combination of E. bulbosa and S. polyanthum extracts possesses significant antihyperuricemic potential and may serve as a candidate for the development of stable phytopharmaceutical formulations for hyperuricemia therapy
Co-Authors Alia, Rahmah Azizah, Sarah Jumrodah Jumrodah, Jumrodah Najhah, Nor Rezqiyatun Noor Hujjatusnaini Nuridah, Nuridah Nurindahsari, Lilin Ika Pitria, Pitria Rosida, Anis Siti Maysaroh