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BIOMARKER C-REACTIVE PROTEIN (CRP) SEBAGAI PREDIKTOR KOMPLIKASI MAKROVASKULAR PADA PASIEN DIABETES MELITUS TIPE 2 Abror, Yogi; Rahayu, Ira Gustira; Patria, Cecep
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 17 No 1 (2025): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v17i1.2798

Abstract

The prevalence of diabetes mellitus (DM) in Indonesia increased significantly in recent years, with type 2 diabetes mellitus as the most common form. Type 2 DM is strongly associated with macrovascular complications, including coronary heart disease and stroke. Increased fasting blood glucose and C-reactive protein (CRP) levels have been associated with these complications. However, the use of CRP as a predictive biomarker for macrovascular disease in patients with type 2 DM has not been explored. The purpose of this study was to examine the CRP biomarker as a predictor of macrovascular complications in patients with type 2 DM. The findings of this study is to help improve DM management and reduce complications of DM and coronary heart disease. This study was conducted with an Observational Analytic approach to 30 patients type 2 DM selected using a purposive sampling technique. Blood specimens were tested to measure fasting blood glucose and CRP levels, then the results were analyzed using the Saphiro Wilk test followed by the Spearman rank correlation test. The results showed that all participants had fasting blood glucose levels > 200 mg/dL and CRP levels > 5 mg/L. There was a strong positive correlation (R = 0.657) between fasting blood glucose and CRP indicating a relationship between hyperglycemia and blood vessel damage. These findings suggest that CRP may serve as a biomarker to predict macrovascular complications in type 2 DM, thus allowing early detection.
PEMBERDAYAAN MASYARAKAT UNTUK PENCEGAHAN PENYEBARAN TUBERKULOSIS DI DESA TANIMULYA KECAMATAN NGAMPRAH KABUPATEN BANDUNG BARAT DENGAN MENERAPKAN TEKNOLOGI PEMBUATAN HANDSANITIZER BERBAHAN DASAR DAUN SELEDRI (Apium graveolens L.) Marliana, Nina; Kurniati, Iis; Abror, Yogi Khoirul; Patria, Cecep
Jurnal Pengabdian Masyarakat Kesehatan Indonesia Vol. 4 No. 2 (2025): Jurnal Pengabdian Masyarakat Kesehatan Indonesia
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jpmki.v4i2.4218

Abstract

TB remains a global problem. In our country, TB prevention, including thorough handwashing, is a fairly effective health protocol for preventing TB transmission. Hand sanitizer is an alcohol-based hand cleaning liquid used to reduce contaminating bacteria by up to 99.9% by using it without rinsing with water. This liquid contains various ingredients that very quickly kill bacteria on the skin of the hands. Hand sanitizer aims to remove dirt and flora that stick to our hands. Celery (A. graveolens L.) is a type of vegetable plant with a menthol and distinctive celery aroma. Usually, celery is only used as a complementary ingredient in food preparations, but it turns out that celery contains several beneficial compounds such as flavonoids, saponins, tannins, essential oils as antibacterials. Therefore, celery can be used as a hand sanitizer. The practical goal of this PPDM is for the community in Tanimulya Village, Ngamprah District, West Bandung Regency to process celery for use as a hand sanitizer. The method offered is technology transfer through counseling, training, and mentoring. The target of the PPDM program was Tani Mulya Village in West Bandung Regency, given the dense population and high pollution in the area, necessitating hand sanitizer to prevent the spread of tuberculosis through the hands. The results of the PPDM program in Tani Mulya Village showed an increase in community knowledge and skills, as evidenced by the pre- and post-test results. The average pre-test score was 66.2, while the post-test score increased to 75.7.