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All Journal Indonesian Journal of Cancer Journal of Comprehensive Science Blantika : Multidisciplinary Journal
Perdana, I Gede Sukma Okta
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Electrical & Electronics Engineering Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Public Health

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Method of Choice of Anesthesia for Circumcision in Preventing Penile Cancer Perdana, I Gede Sukma Okta; Oki Lestari, Desak Putu
Journal of Comprehensive Science Vol. 4 No. 6 (2025): Journal of Comprehensive Science
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v4i6.3336

Abstract

Circumcision is a common minor surgical procedure performed not only for cultural or religious reasons but also as a preventive measure against infectious diseases and penile cancer. The selection of an appropriate anesthesia method plays a critical role in ensuring patient comfort and procedural effectiveness. This study aims to examine the most suitable anesthesia techniques in circumcision procedures with a focus on their preventive role against penile cancer. The method employed is a systematic literature review of clinical and epidemiological journals discussing the link between circumcision, anesthesia techniques, and penile cancer incidence. The results indicate that local anesthesia, particularly the dorsal penile nerve block, is most recommended due to its efficiency, safety, and minimal postoperative pain. Circumcision is shown to reduce the risk of HPV infection and balanitis, two contributing factors to penile cancer. In conclusion, the appropriate choice of anesthesia in circumcision enhances patient experience and reinforces its role as a preventive measure against penile cancer.
Monitoring Peran Anestesi pada Kasus Laminektomi dan Stabilisasi Posterior pada Cedera Tulang Belakang Asia Skala Impairment B Akibat Spondylolisthesis Grade: Laporan Kasus Perdana, I Gede Sukma Okta; Arnanda, Noor
Blantika: Multidisciplinary Journal Vol. 3 No. 8 (2025): Special Issue
Publisher : PT. Publikasiku Academic Solution

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57096/blantika.v3i8.383

Abstract

Cedera sumsum tulang belakang (SCI) merupakan kondisi neurologis serius yang dapat menyebabkan morbiditas dan kecacatan jangka panjang, seringkali terkait dengan trauma fisik pada tulang belakang dan kondisi lain seperti spondilolistesis, di mana segmen vertebra atas bergeser dan menyebabkan gejala neurologis. Penelitian ini melaporkan kasus seorang pasien laki-laki berusia 40 tahun yang mengeluhkan nyeri leher dan kelemahan ekstremitas setelah jatuh dari pohon dengan leher membentur tanah terlebih dahulu. Pemeriksaan fisik menunjukkan defisit neurologis yang signifikan, dan diagnosis spondilolistesis servikal dikonfirmasi melalui pencitraan. Pasien menjalani laminektomi dekompresif dan stabilisasi posterior untuk mencegah cedera lebih lanjut. Hasilnya menunjukkan bahwa SCI servikal akibat spondilolistesis adalah kondisi yang langka namun mengancam jiwa, dengan morbiditas dan mortalitas yang tinggi. Diagnosis dan penanganan yang tepat sangat penting untuk mencegah cedera lanjutan, dan pendekatan anestesi yang hati-hati juga diperlukan untuk mengurangi risiko komplikasi selama prosedur bedah. Penanganan cepat dan tepat terhadap SCI yang disebabkan oleh spondilolistesis dapat meningkatkan kualitas hidup pasien serta mencegah komplikasi lebih lanjut, menggarisbawahi pentingnya pengelolaan yang tepat dalam kasus ini.
Correlation of Age, Tumor Size, and Histopathological Type with Indicator Tumor Progression of Penile Squamous Cell Carcinoma in Bali Astuti, Ni Luh Putu Vina Juni; Lestari, Desak Putu Oki; Sari, Ni Luh Putu Eka Kartika; Armerinayanti, Ni Wayan; Evayanti, Luh Gde; Perdana, I Gede Sukma Okta
Indonesian Journal of Cancer Vol 19, No 3 (2025): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i3.1340

Abstract

Background: Penile cancer is a rare malignancy globally, but Bali accounts for approximately 40% of Indonesia’s cases. Age, tumor size, and histopathological type are recognized factors influencing penile cancer progression, with grade, depth of invasion, lymph node metastasis, and distant metastasis serving as key indicators. However, the prognostic value of these factors, particularly depth of invasion, remains debated. This study aimed to evaluate the correlation between age, tumor size, and histopathological type with indicators of tumor progression in penile squamous cell carcinoma (SCC) in Bali.Method: A cross-sectional analytical study was conducted on 160 cases of penile SCC. Dependent variables included tumor grade, depth of invasion, and lymph node metastasis, while independent variables were age, tumor size, and HPV status (inferred from histopathology). Age was categorized as 60 or ≥60 years, tumor size as 4 cm or ≥4 cm, and depth of invasion as T1–T4. Multivariate analysis using the chi-square test was performed to assess associations.Results:  Most patients were aged ≥ 60 years, had HPV-independent SCC, tumor size ≥ 4 cm, grade 2 tumors, and T1 depth of invasion, with lymph node metastasis observed in a minority. Multivariate analysis revealed significant correlations between age, tumor size, and histopathological type with grade (p = 0.026, R² = 0.056), depth of invasion (p 0.001, R² = 0.445), and lymph node metastasis (p = 0.004, R² = 0.075). Tumor size demonstrated the strongest association with depth of invasion (OR = 9.618, p 0.001) and lymph node metastasis (OR = 6.846, p 0.001).Conclusion: Tumor size is a significant predictor of both depth of invasion and lymph node metastasis in penile SCC. Clinical assessment of tumor size should be emphasized as a key prognostic factor to guide early intervention strategies in patients with penile SCC in Bali.
Co-Authors Arnanda, Noor Astuti, Ni Luh Putu Vina Juni Desak Putu Oki Lestari Luh Gde Evayanti Ni Wayan Armerinayanti, Ni Wayan Oki Lestari, Desak Putu Sari, Ni Luh Putu Eka Kartika