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Anthelmintic Potential of Annona muricata seed Infusion: An In Vitro Study on Haemonchus contortus in Goats Baihaqi, Zein Ahmad; Lisnanti, Ertika Fitri; Tamara, Safira; Ekawasti, Fitrine; Anggrahini, Santika; Fauziah, Ima
Jurnal Sain Veteriner Vol 43, No 1 (2025): April
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.100652

Abstract

Parasitic infections, particularly those caused by Haemonchus contortus, significantly impact the health and productivity of small ruminants worldwide. Traditional anthelmintic treatments are increasingly challenged by resistance issues, prompting the search for alternative treatments. The objective of this study was to assess the effectiveness of Annona muricata seed infusion on Haemonchus contortus mortality in goats in vitro. The research was conducted from November 2023 to March 2024 at the Laboratory of the Faculty of Agriculture, Islamic University of Kadiri, and BRIN. The method employed was one-way ANOVA. Treatments included a negative control with 0.9% NaCl, 10% concentration infusion, 20% concentration infusion, and albendazole. Mortality rates were assessed at 0.5, 1, 2, 4, 6, 8, 10, and 12-hour intervals. The results revealed that Annona muricata seed infusion contains compounds such as tannins, flavonoids, alkaloids, saponins, and steroids, which are capable of damaging the cuticle and buccal tissues of Haemonchus contortus. Phenolic content was measured at total phenolics of 9.1 mg RE / g Dw, total flavonoids of 4.7 mg RE / g Dw, total tannins of 7.2%, condensed tannins / CT of 3.4%, and hydrolyzable tannins / HT of 3.9%. Infusions at 10% and 20% concentrations achieved 100% mortality of Haemonchus contortus by the 8th hour. Scanning Electron Microscopy (SEM) revealed structural changes in Haemonchus contortus at different infusion concentrations, including wrinkling, irregular lines, and the presence of holes in the cuticle and buccal regions. The infusion of Annona muricata seed infusion is effective as an anthelmintic against Haemonchus contortus, achieving 100% mortality at concentrations of 10% and 20% within 8 hours. The study also demonstrates structural damage to the worms, affirming the potential of Pineapple Peel infusion as a natural parasitic control in small ruminants.
Mangosteen Peel Meal as a Natural Feed Additive: Effects on Production Performance and Feed Efficiency in Antibiotic-Free Broiler Chickens Sadarman, Sadarman; Harahap, Rakhmad Perkasa; Friyanto, Dedi; Hidayatulloh, Muhammad Andika; Maharaja, M. Adil; Nurfitriani, Rizki Amalia; Andriani, Mira; Syahniar, TM; Baihaqi, Zein Ahmad
Jurnal Nutrisi Ternak Tropis Vol. 9 No. 1 (2026): JNT Jurnal Nutrisi Ternak Tropis March
Publisher : Faculty of Animal Science, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jnt.2026.009.01.4

Abstract

This study was conducted to evaluate the effect of different levels of mangosteen peel meal (Garcinia mangostana Linn.) supplementation in commercial rations on feed consumption, body weight gain, and feed conversion ratio of broiler chickens. A total of 100 broiler chicks aged 8 days with uniform body weight were randomly assigned to four dietary treatments with five replications, each consisting of five birds. The treatments were: T1 (control, commercial ration without mangosteen peel meal), T2 (commercial ration + 2.50% mangosteen peel meal), T3 (commercial ration + 3% mangosteen peel meal), and T4 (commercial ration + 3.50% mangosteen peel meal). The experiment was conducted using a Completely Randomized Design (CRD). Data were analyzed using analysis of variance (ANOVA) and Duncan's multiple range test. The results showed that supplementation of mangosteen peel meal up to 3.50% did not significantly affect (P>0.05) feed consumption, body weight gain, and feed conversion ratio of broilers. The average feed consumption ranged from 603 to 640 g/bird, body weight gain ranged from 296 to 310 g/bird, and feed conversion ratio ranged from 1.99 to 2.17. It was concluded that mangosteen peel meal supplementation up to 3.50% in commercial rations did not improve the production performance of broilers.