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Anthelmintic Potential of Annona muricata seed Infusion: An In Vitro Study on Haemonchus contortus in Goats Baihaqi, Zein Ahmad; Lisnanti, Ertika Fitri; Tamara, Safira; Ekawasti, Fitrine; Anggrahini, Santika; Fauziah, Ima
Jurnal Sain Veteriner Vol 43, No 1 (2025): April
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.100652

Abstract

Parasitic infections, particularly those caused by Haemonchus contortus, significantly impact the health and productivity of small ruminants worldwide. Traditional anthelmintic treatments are increasingly challenged by resistance issues, prompting the search for alternative treatments. The objective of this study was to assess the effectiveness of Annona muricata seed infusion on Haemonchus contortus mortality in goats in vitro. The research was conducted from November 2023 to March 2024 at the Laboratory of the Faculty of Agriculture, Islamic University of Kadiri, and BRIN. The method employed was one-way ANOVA. Treatments included a negative control with 0.9% NaCl, 10% concentration infusion, 20% concentration infusion, and albendazole. Mortality rates were assessed at 0.5, 1, 2, 4, 6, 8, 10, and 12-hour intervals. The results revealed that Annona muricata seed infusion contains compounds such as tannins, flavonoids, alkaloids, saponins, and steroids, which are capable of damaging the cuticle and buccal tissues of Haemonchus contortus. Phenolic content was measured at total phenolics of 9.1 mg RE / g Dw, total flavonoids of 4.7 mg RE / g Dw, total tannins of 7.2%, condensed tannins / CT of 3.4%, and hydrolyzable tannins / HT of 3.9%. Infusions at 10% and 20% concentrations achieved 100% mortality of Haemonchus contortus by the 8th hour. Scanning Electron Microscopy (SEM) revealed structural changes in Haemonchus contortus at different infusion concentrations, including wrinkling, irregular lines, and the presence of holes in the cuticle and buccal regions. The infusion of Annona muricata seed infusion is effective as an anthelmintic against Haemonchus contortus, achieving 100% mortality at concentrations of 10% and 20% within 8 hours. The study also demonstrates structural damage to the worms, affirming the potential of Pineapple Peel infusion as a natural parasitic control in small ruminants.
Analisis Usability Sistem Lalu Lintas Sistem Informasi Kesehatan Hewan Nasional (LaLin iSIKHNAS) melalui Cognitive Walkthrough untuk Optimalisasi Pelaporan SKKH Fikriya, Arina Ashfa; Baihaqi, Zein Ahmad; Sihabudin, Ilham Fattra; Saputra, Tri; Zamri, M Yusuf Zidani; Havid, Achmad; Zidan, Muhamad
Jurnal Komputer Teknologi Informasi Sistem Informasi (JUKTISI) Vol. 4 No. 2 (2025): September 2025
Publisher : LKP KARYA PRIMA KURSUS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62712/juktisi.v4i2.600

Abstract

Sistem informasi digital berperan penting dalam mendukung pengambilan keputusan berbasis data di sektor kesehatan hewan. Di Indonesia, Sistem Informasi Kesehatan Hewan Nasional (iSIKHNAS) dikembangkan sebagai platform nasional untuk mengelola data kesehatan hewan, termasuk modul LaLin yang berfungsi memfasilitasi pelaporan dan pemantauan lalu lintas ternak. Penelitian ini bertujuan mengevaluasi usability modul LaLin menggunakan metode Cognitive Walkthrough (CW), dengan menekankan pada pengalaman pengguna baru dalam menyelesaikan skenario pelaporan Surat Keterangan Kesehatan Hewan (SKKH). Lima responden dilibatkan dalam pengujian dengan skenario terstruktur. Hasil penelitian menunjukkan bahwa dari aspek learnability dan effectiveness , seluruh responden mampu menyelesaikan tugas dengan tingkat keberhasilan 100% tanpa kesalahan. Namun, pada aspek efficiency ditemukan hambatan, khususnya pada pengisian form dan proses penyimpanan data yang membutuhkan waktu lebih lama. Rekomendasi perbaikan difokuskan pada penyederhanaan form, validasi input otomatis, serta optimasi performa penyimpanan. Dengan penerapan rekomendasi ini, LaLin diharapkan dapat lebih mendukung keterlacakan ternak, meningkatkan kualitas data surveilans, serta memperkuat keberlanjutan iSIKHNAS.