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Pneumonia ANALISIS RASIONALITAS PENGGUNAAN ANTIBIOTIK DAN PENGARUHNYA TERHADAP LAMA RAWAT INAP PASIEN PNEUMONIA DI RSUD AHMAD YANI METRO, LAMPUNG: ANALYSIS OF THE RATIONALITY OF ANTIBIOTIC USE AND ITS EFFECT ON THE LENGTH OF HOSPITAL STAY IN PNEUMONIA PATIENTS AT RSUD JENDERAL AHMAD YANI METRO, LAMPUNG Asti, Windi; Sarnianto, Prih; Sumiyati, Yati; Syahputri, Devina Harti; Suri, Nurma
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2521

Abstract

Pneumonia is an acute infectious disease that affects lung tissue and is caused by bacteria, fungi, viruses, and parasites, leading to inflammation of the lung parenchyma and accumulation of inflammation in the respiratory tract. In Lampung Province, there was an increase in pneumonia case detection coverage, from 39.8% in 2020 to 40.6% in 2021. At RSUD Ahmad Yani in Metro City, Lampung, pneumonia ranks among the top 10 most common diseases. The purpose of this study was to evaluate the rationality and appropriateness of antibiotic use according to treatment guidelines in pneumonia patients. This study employed an observational descriptive-analytic design with a cross-sectional approach and data collection from patient medical records using purposive sampling. The samples consisted of inpatient records diagnosed with pneumonia infection at RSUD Ahmad Yani in Metro City during January–December 2023. Data were obtained retrospectively through medical record reviews of inpatients. Quantitative analysis of antibiotic use was conducted using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) method, while qualitative analysis utilized the Gyssens algorithm. Statistical calculations were performed using SPSS software with Spearman’s correlation test. In this study, from 190 antibiotic prescriptions, the ATC/DDD value was 138.18 DDD per 100 patient-days. The correlation between the rationality of antibiotic use and length of hospital stay showed a Spearman correlation coefficient of 0.42, indicating a moderate positive correlation; however, the significance value of 0.567 indicated that this relationship was not statistically significant.   Keywords : ATC/DDD, Gyssens, Length of Stay (LOS), Pneumonia, Hospital
ANALISIS KUALITATIF DAN KUANTITATIF PENGGUNAAN ANTIBIOTIK PADA PASIEN PASCA OPERASI LAPAROTOMI DI RUANG ICU RSUD JENDERAL AHMAD YANI METRO LAMPUNG TAHUN 2023: ANALISIS KUALITATIF DAN KUANTITATIF PENGGUNAAN ANTIBIOTIK PADA PASIEN PASCA OPERASI LAPAROTOMI DI RUANG ICU RSUD JENDERAL AHMAD YANI METRO LAMPUNG TAHUN 2023 Kurniati, Rizki; Sumiyati, Yati; Ramadaniati, Hesty Utami; Syahputri, Devina Harti
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2522

Abstract

Laparotomy is a surgery performed to open the abdomen, a form of major surgery by cutting the layers of the abdominal wall, risking causing infection of the surgical wound where antibiotics are given as treatment. Antibiotic resistance can lead to increased morbidity, mortality and health costs, therefore there needs to be an analysis for the use of antibiotics. The analysis of the use of antibiotics was carried out in the ICU room of the General Ahmad Yani Metro Lampung Hospital with the aim of analyzing how to use antibiotics qualitatively and quantitatively. The method used is descriptive with retrospective data collection from the period of January 1 to December 31, 2023. The qualitative analysis of the use of antibiotics used the Gyssens method and quantitatively with the ATC/DDD du 90% method. The sample of this study consisted of 52 patients after laparotomy surgery in the ICU room of General Ahmad Yani Metro Hospital Lampung, where based on the inclusion and exclusion criteria determined. Based on the results of the analysis of antibiotic use with the Gyssens method, 83.8% used antibiotics non-adherence (category 0) and 16.2% used antibiotics adherence (categories VIA and V). Analysis of the use of antibiotics using the ATC/DDD method obtained that Seftriaxone had the highest DDD with DDD/100 patients – 76.4 DDD per day and those in the DU segment of 90% were Seftriaxone and Metronidazole.    Keywords: ATC/DDD du 90%, Gyssens, Laparotomy, Quantitative, Qualitative