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All Journal Indonesian Journal of Human Nutrition Journal of Public Health Sciences Journal of Diverse Medical Research: Medicosphere
Mahroos, Rifda El
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Dentistry Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences

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Role of Ficus carica in Alleviating Chronic Hypoxia Impact in Rat’s Lungs Anggraini, Dini; Meliala, Andreanyta; Siswanto; Fitria, Laksmindra; Narwidina, Paramita; Mahroos, Rifda El; Sudesty, Shellya Puti
Indonesian Journal of Human Nutrition Vol. 11 No. 2 (2024)
Publisher : Department of Nutrition, Faculty of Health Sciences, Universitas Brawijaya Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.ijhn.2024.011.02.3

Abstract

Chronic Intermittent Hypoxia (CIH) can initiate oxidative stress and inflammation. Ficus carica is known to contain antioxidant compounds capable of suppressing oxidative stress. This study aims to investigate the protective role of Ficus carica puree (FCP) on the levels of Malondialdehyde (MDA), Superoxide Dismutase (SOD), SOD/MDA ratio, Platelet Lymphocyte Ratio (PLR), and Tumor Necrosis Factor-α (TNF-α) in the lungs of rats induced by CIH. Rats were treated with FCP at doses of 1.25 ml/200g (CIH-F1), 2.5 ml/200g (CIH-F2), and 5 ml/200g (CIH-F3). All rats, except for the neutral control group, were subjected to chronic intermittent hypoxia (CIH) for 4 hours/day for 30 days. The CIH-F2 and CIH-F3 groups demonstrated significantly lower levels of lung MDA compared to the CIH group. The CIH-F3 group showed a considerably lower level of lung SOD compared to the CIH group. However, the SOD/MDA exhibited a considerably greater value in the CIH-F3 induction group compared to the other groups. The TNF-α in lungs and PLR levels were significantly lower in the CIH-F3 group than in the CIH group. These findings suggest that FCP may serve as a functional food to mitigate the negative impact of hypoxic circumstances on lung health.
The Role Of Motility And Gastric Acid Secretion in The Pathophysiology of Gastroesophageal Reflux Disease (GERD): A Literature Review el mahroos, rifda
Journal of Diverse Medical Research : Medicosphere Vol. 2 No. 9 (2025): J Divers Med Res 2025
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v2i9.215

Abstract

Introduction: Gastroesophageal reflux disease (GERD) is a chronic disorder of the upper gastrointestinal tract that involves a complex interaction between physiologic and pathologic factors. The two main components that play a role in this dynamic are gastric motility and acid secretion. Methods: This review used a narrative literature review approach by searching the current scientific literature from various databases between 2015-2024. Discussion: Normal gastric motility maintains gastric emptying efficiency and lowers the risk of reflux, while disorders such as delayed gastric emptying increase intragastric pressure and trigger reflux. Excessive secretion of gastric acid, especially HCl and pepsin, amplifies the aggressive nature of gastric contents and exacerbates damage to the esophageal mucosa. These two aspects interact to create an imbalance between protective and aggressive factors in GERD. Conclusion: The interplay between gastric motility and acid secretion plays a key role in the transition from physiologic to pathologic mechanisms in GERD, so a thorough understanding of both is important in diagnosis and treatment strategies.
Assistive Technology to Support Medical Professionals for Disaster Management Devi, Debrina Kusuma; Yuliwulandari, Rika; Febriawan, Zulfan; Mahroos, Rifda El; Khan, Hafiz Tareq Abdullah
Journal of Public Health Sciences Vol. 5 No. 01 (2026): Journal of Public Health Sciences
Publisher : The Indonesian Institute of Science and Technology Research

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56741/IISTR.jphs.001436

Abstract

Medical assistive technology plays a crucial role in enhancing response and recovery efforts during disasters. This technology includes advanced tools and devices designed to support medical professionals in assessing, treating, and managing patients in high-pressure disaster situations. This paper will explore the medical assistive technology to enhance disaster management. This literature review was conducted via searching in databases such as PubMed, Science Direct, Google Scholar, and Scopus using keywords such as “technology for disaster management”; “pharmaceutical technology for disaster”; “health information”; “communication and technology”; and “disaster medicine technology, robotic, and IoT for healthcare”. The result showed that several tools and software were developed in many countries such as 3D printing for pharmaceuticals for medication printing, drone technology for delivering medical equipment, drugs, and blood, Emergency Medical Information Systems (EMIS), virtual reality (VR) for disaster medicine training, robotics, and innovative mobile applications like SaveMyLife, mental health applications, and rapid DNA technology for disaster victim identification. Using the Health System Resilience Framework, this study highlights how these technologies strengthen service delivery, workforce capacity, and information systems in emergencies. Despite their benefits, most innovations originate in high-income countries, raising challenges for equitable adoption. Future research should address scalability, local adaptation, and ethical considerations to enhance health system resilience in low-resource settings.
Co-Authors Debrina Kusuma Devi Dini Anggraini, Dini Febriawan, Zulfan Khan, Hafiz Tareq Abdullah Laksmindra Fitria Meliala, Andreanyta Narwidina, Paramita Rika Yuliwulandari Siswanto Sudesty, Shellya Puti