Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Biologica Samudra
MZ, Kartika
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Immunology & microbiology Veterinary

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Quantitative Analysis of Sibutramine Hydrochloride in Slimming Herbal Medicines in Banda Aceh Using UV-Vis Spectrophotometry Ruhul Maghfirah; Farida, Mutia; Purnama, Agnia; Afifi, Muhammad Ridho; MZ, Kartika; Rahmawati, Erda
JURNAL BIOLOGICA SAMUDRA Vol 7 No 1 (2025): Biologica Samudra
Publisher : Program Studi Biologi, Fakultas Teknik, Universitas Samudra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jbs.v7i1.11763

Abstract

Sibutramine hydrochloride is a chemical compound that was once often used as a weight loss drug. This drug is hazardous if used illegally in herbal medicine because it can cause health problems such as kidney failure, heart attacks, and strokes. BPOM has banned its use in herbal medicine, but until now herbal medicine containing sibutramine hydrochloride is still on the market. This study aims to determine the levels of Sibutramine Hydrochloride contained in slimming herbal medicine. The samples used in this study consisted of four brands of slimming herbal medicine that are not registered with BPOM, coded A, B, C, and D, which were obtained from several shops in Baiturrahman District, Banda Aceh City. Sampling was carried out using the total sampling method and then analyzed quantitatively using UV-Vis spectrophotometry. The results of the analysis showed that the four samples were positive for containing Sibutramine Hydrochloride with an average level of 31.69% of herbal medicine sample A; 39.88% of herbal medicine sample B; 7.09% of herbal medicine sample C; and 36.60% of herbal medicine sample D. Therefore, stricter examination and supervision of the circulation of slimming herbal medicine products in the Banda Aceh city area are needed to protect public health.
Antibacterial Activity of Triterpenoid from The Leaves of Tahi Ayam (Lantana camara Linn) MZ, Kartika; Suryati, Suryati; Efdi, Mai
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 8, No 3 (2023): October 2023
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v8.i3.110

Abstract

Tahi Ayam (Lantana camara Linn) is known as the herbal plant to cure several diseases and has been used in folk medicine. The result of this study indicates that the isolated compound and the ethyl acetate fraction are components having antibacterial activity. The isolated compound from the ethyl acetate fraction from the leaves of the Lantana camara Linn plant is 9-hydroxy-Lantadene A. The compound includes the triterpenoid compound group, the molecular formula is C35H52O6, and another name is 22-angeloiloxy-9-hydroxy-3-oxo-olean-12-en-28-oat. The antibacterial activity of this compound was determined by looking at the inhibition zone of the test bacteria, namely Staphylococcus aureus as gram-positive and Escherichia coli as gram-negative. The treatment has been using the disc diffusion method and using amoxicillin as a control positive. The result of the antibacterial activity test revealed that both 9-hydroxy-Lantadene A and the ethyl acetate fraction exhibited antibacterial activity. Becouse there are inhibition zones around the discs at concentrations of 10 μg/disk and 5 μg/disk.
Co-Authors Afifi, Muhammad Ridho Mai Efdi Mutia Farida, Mutia Purnama, Agnia Rahmawati, Erda Ruhul Maghfirah Suryati Suryati