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Quantitative Analysis of Sibutramine Hydrochloride in Slimming Herbal Medicines in Banda Aceh Using UV-Vis Spectrophotometry Ruhul Maghfirah; Farida, Mutia; Purnama, Agnia; Afifi, Muhammad Ridho; MZ, Kartika; Rahmawati, Erda
JURNAL BIOLOGICA SAMUDRA Vol 7 No 1 (2025): Biologica Samudra
Publisher : Program Studi Biologi, Fakultas Teknik, Universitas Samudra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33059/jbs.v7i1.11763

Abstract

Sibutramine hydrochloride is a chemical compound that was once often used as a weight loss drug. This drug is hazardous if used illegally in herbal medicine because it can cause health problems such as kidney failure, heart attacks, and strokes. BPOM has banned its use in herbal medicine, but until now herbal medicine containing sibutramine hydrochloride is still on the market. This study aims to determine the levels of Sibutramine Hydrochloride contained in slimming herbal medicine. The samples used in this study consisted of four brands of slimming herbal medicine that are not registered with BPOM, coded A, B, C, and D, which were obtained from several shops in Baiturrahman District, Banda Aceh City. Sampling was carried out using the total sampling method and then analyzed quantitatively using UV-Vis spectrophotometry. The results of the analysis showed that the four samples were positive for containing Sibutramine Hydrochloride with an average level of 31.69% of herbal medicine sample A; 39.88% of herbal medicine sample B; 7.09% of herbal medicine sample C; and 36.60% of herbal medicine sample D. Therefore, stricter examination and supervision of the circulation of slimming herbal medicine products in the Banda Aceh city area are needed to protect public health.
DETERMINATION OF LEAD (PB) CONTAMINATION IN LETTUCE (Lactuca sativa L.) FROM VARIOUS COLLECTION SOURCES IN BANDA ACEH, INDONESIA Muhammad Afifi; Suprida Suprida; Agnia Purnama; Ruhul Maghfirah; Mutia Farida
Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Vol. 8 No. 1 (2026): Literasi Artikel Penelitian Kimia
Publisher : Program Studi Kimia, Fakultas MIPA, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/jc.v8i1.7164

Abstract

Lettuce (Lactuca sativa L.) is a vegetable that is often consumed fresh, therefore the safety of its contents needs attention, especially regarding contamination with the heavy metal lead (Pb). This study aims to analyze Pb levels in lettuce obtained from the supermarket, traditional market, and local garden in Banda Aceh City using the Atomic Absorption Spectrophotometry method (AAS) and to evaluate differences in Pb content based on the source of acquisition. The analytical method was validated through linearity, sensitivity, and precision. The Pb calibration curve shows a good linear relationship with a coefficient of determination (R²) value of 0.9931. The limit of detection (LOD) and limit of quantification (LOQ) values were 0.162 mg/L and 0.492 mg/L, respectively. The precision test at low concentrations yielded a %RSD value of 4.91%, which met the method validation criteria. The results of the analysis showed that the Pb content in lettuce from the supermarket, traditional market, and local garden was 2.54 ± 0.12 mg/kg, 2.60 ± 0.07 mg/kg, and 2.38 ± 0.08 mg/kg, respectively, all of which exceeded the maximum Pb contamination limit according to BPOM (0.2 mg/kg). The one-way ANOVA test showed that there was no statistically significant difference (p > 0.05) between Pb levels among the different sources.