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All Journal MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Jurnal Medika: Medika Science: Indonesian Journal of Science
Tasrif, Ari Bandana
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Agriculture, Biological Sciences & Forestry Chemistry Dentistry Health Professions Mathematics Medicine & Pharmacology Nursing Physics Public Health Veterinary

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VASOGENIC EDEMA AND HYDROCEPHALUS AS COMPLICATIONS OF GLIOBLASTOMA Tasrif, Ari Bandana
MEDALION JOURNAL: Medical Research, Nursing, Health and Midwife Participation Vol. 6 No. 4 (2025): December
Publisher : PT. Radja Intercontinental Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59733/medalion.v6i4.223

Abstract

Glioblastoma is the most aggressive and common primary brain tumor in adults, characterized by rapid growth, infiltrative behavior, and poor prognosis despite multimodal treatment. Among its most significant complications are vasogenic edema and hydrocephalus, which exacerbate intracranial hypertension and contribute substantially to morbidity and mortality. We report the case of a 59-year-old male who presented with progressive decreased consciousness, severe headaches, right-sided weakness, and visual disturbances. Neuroimaging revealed a left temporoparietal mass with cystic, solid, and necrotic components, accompanied by extensive vasogenic edema, midline shift, and obstructive hydrocephalus. Histopathological examination confirmed glioblastoma, WHO grade IV. The patient was treated with intravenous dexamethasone and acetazolamide, resulting in improved consciousness and partial symptomatic relief. This case illustrates the pathophysiological role of blood–brain barrier disruption in vasogenic edema and cerebrospinal fluid flow obstruction in hydrocephalus. Dexamethasone remains the cornerstone of symptomatic management for edema, while acetazolamide may provide temporary benefit in hydrocephalus, although its long-term efficacy is limited. The coexistence of these complications significantly worsens prognosis, and treatment primarily focuses on symptom control and quality of life. Prompt recognition and appropriate management are essential to stabilize patients, even though overall survival in glioblastoma remains limited.
Edukasi Penanggulangan Gizi Buruk pada Balita Dalam Pemantauan Rumah Sehat di Desa Pantai Cermin Syafriani, Syafriani; Tasrif, Ari Bandana; Irinericy, Rani; Sahariah, Sahariah; Starlista, Viva; Rustanti, Nita; Muniroh, Muniroh; Irhamna, Mailisa
Jurnal Medika: Medika in progres
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/wksx2652

Abstract

Masalah gizi buruk pada balita masih menjadi permasalahan kesehatan masyarakat di Indonesia yang dapat berdampak pada pertumbuhan fisik, perkembangan kognitif, serta kualitas sumber daya manusia di masa depan. Salah satu upaya yang dapat dilakukan untuk mencegah masalah tersebut adalah melalui peningkatan pengetahuan ibu mengenai pemenuhan gizi balita. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan ibu balita mengenai penanggulangan gizi buruk melalui edukasi kesehatan dalam pemantauan rumah sehat. Kegiatan dilaksanakan di Desa Pantai Cermin, Kecamatan Tapung, Kabupaten Kampar dengan sasaran ibu yang memiliki balita. Metode kegiatan meliputi tahap observasi, persiapan, pelaksanaan edukasi kesehatan, serta evaluasi kegiatan. Hasil kegiatan menunjukkan bahwa ibu-ibu peserta memiliki antusiasme yang tinggi selama kegiatan penyuluhan serta menunjukkan peningkatan pemahaman mengenai penyebab, dampak, serta upaya pencegahan gizi buruk pada balita. Edukasi kesehatan yang dilakukan secara langsung terbukti efektif dalam meningkatkan pengetahuan masyarakat mengenai pentingnya pemenuhan gizi seimbang bagi balita. Kegiatan ini diharapkan dapat mendorong perubahan perilaku keluarga dalam pemenuhan gizi anak serta meningkatkan kesadaran masyarakat dalam melakukan pemantauan pertumbuhan balita secara rutin melalui kegiatan posyandu.
Hemorrhagic Transformation in Cardioembolic Stroke with Anticoagulant Use: A Case Report Tasrif, Ari Bandana
Science: Indonesian Journal of Science Vol. 2 No. 5 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/sciencejurnalkesehatanmasyarakatdanteknologiterapan.v2i5.395

Abstract

Embolic stroke is a subtype of ischemic stroke characterized by the sudden onset of severe neurological deficits due to abrupt vascular occlusion. One of its important complications is hemorrhagic transformation (HT), defined as bleeding within infarcted brain tissue. This case report describes a 49-year-old male with a history of prior stroke and warfarin use who presented with decreased consciousness. Brain CT scan revealed extensive cerebral infarction with hemorrhagic transformation classified as HI-1 based on the European Cooperative Acute Stroke Study (ECASS) criteria. HT results from a complex interplay between blood–brain barrier disruption, reperfusion injury, and risk factors such as large infarct size and anticoagulant use. Management includes hemodynamic stabilization, discontinuation and reversal of anticoagulation, and intracranial pressure control. Although HI-1 is considered less severe than parenchymal hematoma, it still carries significant clinical implications, particularly when associated with cerebral edema. Early detection and appropriate management are essential to improve patient outcomes.
Co-Authors Irhamna, Mailisa Irinericy, Rani Muniroh, Muniroh Nita Rustanti Sahariah, Sahariah Starlista, Viva Syafriani Syafriani, Syafriani