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ANALISIS BIAYA KEMOTERAPI PADA PASIEN RAWAT INAP KANKER PAYUDARA PESERTA JKN DI RSUD ULIN BANJARMASIN Aisyah, Noor; Andayani, Tri Murti; Puspandari, Diah Ayu
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3, No 2 (2018)
Publisher : Akademi Farmasi ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (8.262 KB)

Abstract

Kanker payudara merupakan jenis penyakit katastropik yaitu penyakit yang high cost, high volume dan high risk yang menyebabkan terjadinya pembengkakan biaya penyakit. Berdasarkan data klaim Indonesian-Case Based Groups sampai dengan bulan bayar Januari 2016, penyakit kanker menduduki urutan kedua setelah jantung yang paling banyak membutuhkan biaya pengobatan, yaitu Rp1,8 triliun. Tujuan penelitian ini untuk mengetahui gambaran kemoterapi dan mengetahui berapa besar perbedaan biaya riil dengan tarif INA-CBGs pada pasien kemoterapi kanker payudara rawat inap peserta JKN di RSUD Ulin  Banjarmasin.Penelitian ini merupakan penelitian analisis farmakoekonomi dengan perspektif rumah sakit terhadap biaya medis langsung (direct medical cost) dan data diambil secara retrospektif. Objek pada penelitian ini adalah berkas keuangan rumah sakit pelayanan rawat inap dan rekam medis pasien kanker payudara peserta JKN periode bulan Januari – Oktober 2017 di RSUD Ulin Banjarmasin. Sampel yang digunakan sebanyak 259 episode perawatan. Analisis data dilakukan dengan one sample test untuk membandingkan rata-rata biaya riil dengan tarif INA-CBGs.Hasil penelitian menunjukkan gambaran kemoterapi pada pasien kanker payudara rawat inap peserta Jaminan Kesehatan Nasional di RSUD Ulin Banjarmasin periode Januari-Oktober 2017 adalah docetaxel 62,36%, siklofosfamid 52,35% dan epirubicin 40%. Besarnya perbedaan antara biaya riil dengan tarif paket INA-CBGs yaitu sebesar Rp662.143.091 (259 episode perawatan). Sedangkan rata-rata biaya riil dengan kemoterapi per episode perawatan yaitu pada tingkat keparahan I sebesar Rp.4.502.210, pada tingkat keparahan II sebesar Rp8.239.624 dan pada tingkat keparahan III sebesar Rp7.403.713.
KOMPARASI PENJUALAN OBAT PREKURSOR SEBELUM DAN SESUDAH INSPEKSI BPOM DI APOTEK KIMIA FARMA 61 VETERAN BANJARMASIN TAHUN 2017 Noor Aisyah; Desi Rahmida; Mochammad Maulidie Alfiannor Saputera; Shela Puzi Dina
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Submission of pharmaceutical drug precursors for hard drugs to patients must be prescribed by a doctor. The use of inappropriate precursors can be misused for the manufacture of illegal narcotics and psychotropics, including Pseudoephedrine. The purpose of this study was to determine the comparison of the sales of pseudoephedrine precursor drugs, hard drug groups that used prescriptions and did not use prescriptions before and after the inspection of the BPOM. This research was conducted at Kimia Farma Pharmacy No. 61 Veteran Banjarmasin with descriptive method. The population taken in the study was the sale of precursor drugs containing pseudoephedrine hard drug, three months before and three months after the BPOM inspection. The samples in this study were data on drug sales in the KIS system, the drugs were Aldisa sr sr, Lapifed, SR Rhinos, Rhinofed, Trifed and Tremenza. Data analysis was the Mann Whitney U-test. The results showed that there was no difference in sales of hard drug precursor of the pseudoephedrine type using prescription before and after BPOM inspection based on the Mann Whitney U-test with a significance value of0.579(p>0.05), and there were differences in the drug sales that did not use prescription with a significance value of0,000(p <0.05).
KOMPARASI BIAYA RIIL DENGAN TARIF INA-CBG’s PADA PASIEN RAWAT INAP KEMOTERAPI KANKER PARU DI RSUD ULIN BANJARMASIN noor aisyah; Yoga Saputra; Mardiana Mardiana
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.401

Abstract

Kanker paru merupakan penyakit yang memiliki tingkat morbiditas yang tinggi hampir diseluruh dunia. Kanker paru termasuk penyakit katastropik yang membutuhkan biaya tinggi dalam pengobatannya serta memiliki komplikasi yang dapat mengancam jiwa. Penelitian bertujuan untuk mengetahui perbedaan antara biaya riil dengan tarif INA-CBGs pada pasien rawat inap kemoterapi kanker paru peserta JKN di RSUD Ulin Banjarmain. Metode penelitian non eksperimental dengan rancangan cros sectional, diambil secara retrospektif dari berkas klaim JKN, penelitian merupakan penelitian yang bersifat komparatif. Teknik sampling yang digunakan adalah sampling jenuh jumlah, dengan jumlah sampel 49 pasien (108 episode perawatan). Instrument yang digunakan adalah lembar observasi, data diambil pada periode tahun 2018 dan dimasukkan dalam lembar observasi. Analisis data yang digunakan adalah uji one sample T-tes dan Mann-whitney Berdasarkan hasil penelitian dapat disimpulkan bahwa ada selisih positif antara total biaya riil dengan total tarif INA-CBGs pada tingkat keparahan I Rp.33.764.472, Tingkat keparahan II Rp.101.772.251 dan Tingkat keparahan III Rp.17.198.887. Berdasarkan uji SPSS menunjukan bahwa pada tingkat keparahan I dan II (kelas 1,2 dan kelas 1) tidak meiliki perbedaan secara signifikan karena nilai Æ¿ > 0,05, sedangkan tingkat keparahan I,II dan III (kelas 3) memiliki perbedaan secara signifikan karena nilai Æ¿ < 0,05.
ANALISIS BIAYA KEMOTERAPI PASIEN KANKER PAYUDARA DAN KANKER SERVIKS DI RSUD ULIN BANJARMASIN Noor Aisyah; Akhmad Syarifuddin; Putri Amami; Mardiana Mardiana
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.500

Abstract

Breast cancer and cervical cancer are the most cancers in Indonesia that require public health action and intervention.Cancer financing at Jamkesmas 2012 ranked second as much Rp.144.7M.The aim of the study was to find out the comparison between the real costs and the INA-CBGs package rates for breast cancer chemotherapy patients and cervical cancer JKN participants in RSUD Ulin Banjarmain.Nonexperimental research method with cross-sectional data design was taken retrospectively from JKN claim file in 2018, the study is comparative.Research samples in cancer patients were 306 episodes of care and 127 episodes of care in cervical cancer patients.Data analysis was tested with one-sample t-test to see the comparison of average real costs with INA CBG rates.Based on the results of one-sample t-test, it shows that in all severity levels(I,II,III) there is a significant difference (p<0.05) between real costs and INA-CBGs package rates, except for the severity of I (class1) values p>0.05. The average cost for breast cancer patients to pay for each chemotherapy, the severity I is Rp.4,496,831 and the severity II is Rp.7,797,032.The average cost in patients with cervical cancer chemotherapy, at the severity level I Rp.3,388,248, the severity level II Rp.3,475,007 and the severity level III Rp.3,535,933.
Characterization of Chitosan from the Haliling Snail (Filopaludina javanica) Shell in South Kalimantan Siska Musiam; Noor Aisyah
CHEMICA: Jurnal Teknik Kimia Vol 7, No 2 (2020): Desember 2020
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26555/chemica.v7i2.18013

Abstract

Chitosan is a renewable natural polymer derived from chitin which can be found in many invertebrate animals. Chitosan has non-toxic properties, is easily broken down (biodegradable and bioresorbable), and is able to adapt to its environment (biocompatibility). This study aims to characterize chitosan produced from haliling (Filopaludina javanica) shell waste originating from South Kalimantan. Haliling meat is consumed as a side dish by the people of South Kalimantan so that the shell becomes a waste that can be used as raw material for chitosan. Chitosan characterization included determination of yield, solubility test, calculation of the degree of deacetylation with Fourier Transform Infra Red (FTIR), as well as observing the crystallinity and morphology of the yield compounds by X-Ray Diffraction (XRD) and Scanning Electron Microscope (SEM). The yield of chitosan obtained was 8.890% with the best solubility at 0.1 N HNO3 N. The FTIR analysis of chitosan obtained a degree of deacetylation of 60.581%. XRD and SEM data showed a crystallinity index of 52.945% with a granular surface.
ANALISIS BIAYA KEMOTERAPI PADA PASIEN RAWAT INAP KANKER PAYUDARA PESERTA JKN DI RSUD ULIN BANJARMASIN Noor Aisyah; Tri Murti Andayani; Diah Ayu Puspandari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 2 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (177.474 KB) | DOI: 10.36387/jiis.v3i2.189

Abstract

Kanker payudara merupakan jenis penyakit katastropik yaitu penyakit yang high cost, high volume dan high risk yang menyebabkan terjadinya pembengkakan biaya penyakit. Berdasarkan data klaim Indonesian-Case Based Groups sampai dengan bulan bayar Januari 2016, penyakit kanker menduduki urutan kedua setelah jantung yang paling banyak membutuhkan biaya pengobatan, yaitu Rp1,8 triliun. Tujuan penelitian ini untuk mengetahui gambaran kemoterapi dan mengetahui berapa besar perbedaan biaya riil dengan tarif INA-CBGs pada pasien kemoterapi kanker payudara rawat inap peserta JKN di RSUD Ulin  Banjarmasin.Penelitian ini merupakan penelitian analisis farmakoekonomi dengan perspektif rumah sakit terhadap biaya medis langsung (direct medical cost) dan data diambil secara retrospektif. Objek pada penelitian ini adalah berkas keuangan rumah sakit pelayanan rawat inap dan rekam medis pasien kanker payudara peserta JKN periode bulan Januari – Oktober 2017 di RSUD Ulin Banjarmasin. Sampel yang digunakan sebanyak 259 episode perawatan. Analisis data dilakukan dengan one sample test untuk membandingkan rata-rata biaya riil dengan tarif INA-CBGs.Hasil penelitian menunjukkan gambaran kemoterapi pada pasien kanker payudara rawat inap peserta Jaminan Kesehatan Nasional di RSUD Ulin Banjarmasin periode Januari-Oktober 2017 adalah docetaxel 62,36%, siklofosfamid 52,35% dan epirubicin 40%. Besarnya perbedaan antara biaya riil dengan tarif paket INA-CBGs yaitu sebesar Rp662.143.091 (259 episode perawatan). Sedangkan rata-rata biaya riil dengan kemoterapi per episode perawatan yaitu pada tingkat keparahan I sebesar Rp.4.502.210, pada tingkat keparahan II sebesar Rp8.239.624 dan pada tingkat keparahan III sebesar Rp7.403.713.
SINTESIS NANOKITOSAN DARI LIMBAH CANGKANG HALILING (Filopaludina javanica) KALIMANTAN SELATAN Siska Musiam; Noor Aisyah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.547 KB) | DOI: 10.36387/jiis.v4i2.362

Abstract

Haliling (Filopaludina javanica) is usually consumed as a side dish by the people of South Kalimantan by taking part of the meat, then the shell is disposed as untapped waste. This research utilizes the waste from the haliling shell as raw material for chitosan synthesis. Chitosan is a multipurpose natural polymer used in the biomedical field as a protective active drug. Haliling shell powder deproteinated with a solution NaOH 4%(w/v) of 10:1 ratio by refluxing for 2 hours at 100°C. The results of the deproteination reaction were demineralized with a solution of HCl 1 N of 15:1 ratio which was stirred for 2 hours at room temperature. Furthermore, the demineralization reaction results are depigmented with a solution of NaOCl 0.315%(w/v) of 10:1 ratio which was stirred for 2 hours at 40°C to obtain chitin. Deacetylation reaction was carried out on chitin using a solution of NaOH 60%(w/v) of 20:1 ratio by refluxing it for 2 hours at 80°C so that chitosan was obtained. Chitosan nanoparticles were synthesized using the ionic gelation method with sodium tripolyphosphate crosslinker. The product obtained is known as chitosan based on the results of FTIR analysis which shows the emergence of the -NH2 amine group at wave number 3300-3500 cm-1 with an average size of chitosan nanoparticles of 500 nm.
PENENTUAN KADAR FENOLIK TOTAL EKSTRAK ETANOL 96% DAUN TERAP (Artocarpus odoratissimus Blanco) DENGAN METODE SPEKTROFOTOMETRI VISIBEL Anna Khumaira Sari; Noor Aisyah; Erna Prihandiwati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (415.444 KB) | DOI: 10.36387/jiis.v5i1.417

Abstract

Terap leaf (Artocarpus odoratissimus Blanco) is a plant that contains flavonoids which are phenolic groups. These compounds are effectively used as natural antioxidants. Antioxidants function to reduce the speed of lipid peroxidation by giving electrons to free radicals, can make normal molecules. Phenol compounds also have bacteriosid, antihelmintic, analgesic, anti-inflammatory, antimicrobial, anticancer and degenerative diseases. The purpose of this study was to determine the total phenolic levels contained in the terap leaf plants. The terap leaves were obtained from Amuntai City, Hulu Sungai Tengah which were selected based on inclusion and exclusion criteria. Phenolic compounds in terap leaves were extracted using maceration method using 96% ethanol solvent. Qualitative testing of terap leaf was determined using FeCl3 reagent, determination of terap leaf compounds was expressed with gallic acid equivalence value. The method used is Visible Spectrophotometry with Folin ciocalteau reagents. The concentrations used in linear regression curves are 5, 10, 15, 20, 25 and 30µg / mL. Qualitative test results obtained the terap leaf extract positive containing phenolic compounds with marked changes in yellow to green. Based on quantitative test results obtained operating time at minute 1 and the maximum wavelength obtained is 762 nm. Linear regression obtained by y = 0.0213x + 0.117. The value of total phenolic content obtained in the terap leaf extract was 10.56% w / w.
FAKTOR-FAKTOR YANG MEMPENGARUHI BIAYA RIIL PASIEN KEMOTERAPI KANKER PAYUDARA PESERTA JKN DI RSUD ULIN BANJARMASIN Noor Aisyah; Saftia Aryzki; Amaliyah Wahyuni; Tri M Andayani; Diah A Puspandari
JCPS (Journal of Current Pharmaceutical Sciences) Vol 2 No 2 (2019): March 2019
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Data from IARC in 2012 as many as 1.7 million women were diagnosed with breast cancer. Breast cancer is catastrophic, high-cost and life-threatening complications. The claim data for INA-CBGs for cancer is one of the diseases that absorbs the biggest costs. The factors that influence the real costs of breast cancer patients are length of stay, severity, class of care and age. The aim of the study was to determine the factors that affect the real costs of breast cancer chemotherapy patients hospitalized JKN participants in Ulin Banjarmasin Hospital. The study is a pharmacoeconomic analysis study with a hospital perspective on direct medical costs, data taken retrospectively. The study sample was a hospital financial file and a medical record of breast cancer patients at JKN participants for the period of January-October 2017 in Ulin Banjarmasin Hospital with 259 episodes of treatment. To find out the factors that influence the real costs using multivariate linear regression correlation analysis. The results showed that the factors that influence the real costs of chemotherapy patients in breast cancer hospitalized JKN participants in RSUD Ulin Banjarmasin were severity (p = 0,000) and treatment class (p = 0,000). The total cost of medicine from 259 episodes of care is Rp. 669,577,809, average real costs with chemotherapy treatment episodes at severity level I amounted to Rp.4,502,210, II severity level Rp.8,239,624 and III severity level Rp.7,403,713.
PROGRAM BINA DESA DALAM PEMBERDAYAAN MASYARAKAT UNTUK PEMANFAATAN BUDI DAYA IKAN DALAM EMBER DAN AQUAPONIK ERA COVID-19 Mochammad Maulidie Alfiannor Saputera; Noor Aisyah
Jurnal Bakti untuk Negeri Vol 1 No 1 (2021)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

In 2018 the village development program in the Tatah Layap Village was implemented. Activities carried out in 2020 include empowering the community in the cultivation of fish in buckets and aquaponics. This program aims to increase fishery resilience in supporting the community's economy. The program this time is to utilize catfish seeds and kale seeds. The community involved this time is the head of the household who comes from Tatah Layap Village. The number of participants in this activity was 22 people. The method used in this community service is a combination of community empowerment, training and mentoring for 3 days by involving students in 2020 village development program participants. The first step is making bucket containers in breeding catfish seeds which previously activated water media using EM4 for 2 days. Then prepare the materials needed in making aquaponics. Fish farming in buckets and aquaponics is maintained until the harvest process. The results show that the harvest of water spinach is once every 2 weeks within the period of spreading water spinach seeds once and harvesting catfish for 2 months.