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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Journal of Pharmaceutical and Sciences.
Purbowo Sintoro, Henry
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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The Effectiveness of Kombucha Coffee (Coffea canephora) Extract Antioxidant Moisturizer on UV-B Induced Skin Epidermal Thickness Chandra, Lifia; Prameswari, Renata; Arundani, Prima; Purbowo Sintoro, Henry
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 2 (2025): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.2.2025.125-129

Abstract

Background: The exposure to UV-B (280-320 nm) in Indonesia's tropical sunlight leads to the accumulation of free radicals, which in turn causes the formation of dry skin and thickening of the epidermis, a sign of skin photoaging. Topical intervention with moisturizers containing antioxidants is one approach to prevent further damage. The addition of kombucha coffee extract from fermented robusta coffee (Coffea canephora) with SCOBY (symbiotic cultures of bacteria and yeasts) can be a source of antioxidants. Purpose: To evaluate the effect of Coffea canephora extract as an antioxidant moisturizer in reducing epidermal thickness on mice’s back skin exposed to UV-B irradiation. Methods: This research is a true experimental design with a post-test only control design. The sample used in this research is thirty male white mice (Rattus norvegicus), which were divided into six groups and were UV-B irradiated for two weeks with total dosage of 980 mJ/cm2.At the end of the treatment, skin samples were excised and stained histologically with Mollory Azan (MA) to evaluate the thickness of the epidermis. Data obtained were analyzed statically with SPSS. Result: The Kruskal-Wallis test demonstrated significant results (0.0001, p<0.05) across all groups, indicating the efficacy of the kombucha coffee extract antioxidant moisturizer in reducing epidermal thickness. Conclusion: The application of Coffea canephora extract antioxidant moisturizer provided photoprotection against UV-B induced hyperplasia skin epidermis with the concentration of 5% and 10% extract.
Gambaran gaya hidup penderita hipertensi di puskesmas Pamolokan Kecamatan Kota Sumenep Kabupaten Sumenep tahun 2023 Ulfa, Nadiyah; Purbowo Sintoro, Henry; Wibowo, Prajogo; Pratama A., Ronald
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 1 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i1.426

Abstract

Hypertension, a widespread global health issue, significantly contributes to the burden of non-communicable diseases. Its escalating prevalence globally and in Indonesia necessitates a comprehensive understanding of associated lifestyle patterns. This study, conducted at Pamolokan Health Center in Sumenep City District, Sumenep Regency, in 2023, focuses on the lifestyles of hypertensive patients. Globally, hypertension affects a substantial portion of the population, impacting public health significantly. In Indonesia, the prevalence of hypertension has steadily risen, prompting a focused examination of contributing factors. Among 85 hypertensive respondents, those aged 36-45 comprised 74.12%, with females constituting 76.67%. Hypertension severity varied, with 55.29% experiencing grade 1 hypertension. The study assessed lifestyle components, revealing 23.53% smoking, 67.06% favouring salty foods, 52.94% consuming fatty foods, 58.82% indulging in coffee, and 35.29% reporting regular physical activity. Understanding the lifestyle patterns of hypertensive patients is crucial for devising targeted interventions. This study's findings illuminate the interplay between age, gender, hypertension severity, and lifestyle choices. Insights contribute to the hypertension management and prevention discourse, emphasising the imperative of tailored public health strategies to address this global health challenge.
Co-Authors Arundani, Prima Chandra, Lifia Pratama A., Ronald Renata Prameswari Ulfa, Nadiyah Wibowo, Prajogo