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All Journal Jurnal Fitofarmaka Indonesia Jurnal Review Pendidikan dan Pengajaran (JRPP)
Anisa, Rianti
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Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Languange, Linguistic, Communication & Media Medicine & Pharmacology Social Sciences Other

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OPTIMASI METODE EKSTRAKSI KUNYIT HITAM (CURCUMA CAESIA) TERHADAP AKTIVITAS ANTIOKSIDAN HM, Nur Rahmah; Fadliyah, Nurfadhilah; Handayani, Virsa; Anisa, Rianti; Ahmad, Aktsar Roskiana; Malik, Abd.
Jurnal Review Pendidikan dan Pengajaran Vol. 8 No. 2 (2025): Volume 8 No. 2 Tahun 2025
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jrpp.v8i2.44562

Abstract

Kunyit hitam (Curcuma caesia) merupakan tanaman dari keluarga Zingiberaceae yang memiliki potensi sebagai sumber senyawa bioaktif seperti fenol dan antioksidan. Penelitian ini bertujuan untuk mengevaluasi kadar fenol total dan aktivitas antioksidan ekstrak kunyit hitam menggunakan metode peredaman radikal bebas DPPH. Ekstraksi dilakukan dengan metode maserasi dan ultrasonikator pada variasi suhu dan durasi. Hasil penelitian menunjukkan bahwa sampel S1 memiliki kadar fenol tertinggi sebesar 42,122 mg/g dan aktivitas antioksidan tertinggi dengan nilai IC50 sebesar 0,405 ppm. Aktivitas antioksidan menunjukkan korelasi positif dengan kadar fenol total. Penelitian ini menunjukkan potensi kunyit hitam sebagai sumber antioksidan alami yang dapat dikembangkan lebih lanjut.
Antioxidant Activity Test of Sappan (Caesalpinia sappan L.) and Chinese Teak (Senna alexandrina) Extract Combination Using DPPH (1,1 Diphenyl 2 Picrylhydrazyl) Free Radicals Scavenging Method Anisa, Rianti; Naid, Tadjuddin; Malik, Abd.; Nisaa, Nur Rezky Khairun
Jurnal Fitofarmaka Indonesia Vol 10, No 3 (2023): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v10i3.1103

Abstract

Sappan (Caesalpinia sappan L.) is applied as food and traditional medicine. Chinese teak (Senna alexandrina) is a plant from the tropics that can be developed as an antioxidant. This study was conducted to determine the antioxidant activity of the combination of Sappan and Chinese Teak by the DPPH (1,1 Diphenyl 2 Picrylhydrazyl) Free Radical Scavenging method. The extraction method used was maceration with Ethanol 96% as solvent. Determination of antioxidant levels was done quantitatively using the UV-Vis Spectrophotometer instrument at a wavelength of 514 nm. From the results of the study, the regression value obtained for the comparison of Quercetin is y = 3.1303x + 0.2292 with R2 = 0.9974 and IC50 value of 15.899 μg/mL. For the antioxidant activity of Sappan, the regression value y=0.5769x + 18.543 with R2=0.9969 and IC50 value of 54.53 μg/mL, Chinese Teak obtained regression value y=0.1421x + 17.506 with R2=0.9989 and IC50 value of 228.67 μg/mL, and for the combination obtained regression value y=0.4304x + 36.622 with R2=0.9954 and IC50 value of 40.38 μg/mL. The results of this study indicate that the combination of Sappan and Chinese Teak extracts has a very strong antioxidant effect (<50 μg/mL).
Co-Authors ABD. MALIK Ahmad, Aktsar Roskiana Fadliyah, Nurfadhilah HM, Nur Rahmah Nisaa, Nur Rezky Khairun Tadjuddin Naid Virsa Handayani