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All Journal Indonesian Journal of Pharmaceutical Science and Technology MPI (Media Pharmaceutica Indonesiana) Jurnal Fitofarmaka Indonesia PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Abdi Insani Jurnal Pengabdian Masyarakat (ABDIRA) JUKEJ: Jurnal Kesehatan Jompa Proceeding Mulawarman International Conference on Tropical Public Health
Nisaa, Nur Rezky Khairun
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Anti-Inflammatory Activity of Dysmenorrhea Herbal Medicine Through Inhibition of the Cyclooxygenase Enzyme and Identification of Compound in Sambiloto Extract Mus, Nurul Muhlisa; Prasetya, Fajar; Widowati, Lucie; Bafadal, Mentarry; Nisaa, Nur Rezky Khairun; Isnawati, Ani
Indonesian Journal of Pharmaceutical Science and Technology 2024: Suppl. 6, No. 1 (Special Issue for Mulawarman Pharmaceutical Conference)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v6i1.53219

Abstract

Dismenore adalah rasa kram atau nyeri yang terjadi ketika menstruasi. Meskipun efektif dalam pengobatan dismenore, penggunaan AINS jangka panjang dapat menyebabkan efek samping pada sistem gastrointestinal dan terjadi pendarahan. Tujuan penelitian ini adalah untuk mengetahui aktivitas antiinflamasi ramuan jamu dismenore yang terdiri dari ekstrak sambiloto, kunyit, kelor, jahe merah,dan coklat hitam terhadap enzim COX yang ditentukan dengan menggunakan metode TMPD  secara spektrofotometri. Berdasarkan hasil pengujian, diketahui ekstrak sambiloto memiliki aktivitas penghambatan baik pada enzim COX-1 maupun enzim COX-2 dengan persen inhibisi masing-masing sebesar 4.5% (1000 ppm) dan 74.29% (1000 ppm). Berdasarkan hasil analisis metabolomik menggunakan LC-HRMS, salah satu senyawa yang terdeteksi pada sampel ekstrak etanol sambiloto yaitu senyawa turunan andrographolide yaitu 14-Deoxy-11,12-didehydro andrographolide dengan rumus kimia C20H28O4. Senyawa paling melimpah kedua pada ekstrak sambiloto ini terdeteksi oleh ESI positif dengan waktu retensi 9.804 menit dan dengan berat molekul 332,1974.
Pengaruh Edukasi Manajemen Diri terhadap Kualitas Hidup Pasien Diabetes Melitus Tipe II Maesa, Beki; Hajrah; Nisaa, Nur Rezky Khairun
MPI (Media Pharmaceutica Indonesiana) Vol. 6 No. 1 (2024): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v6i1.6519

Abstract

Diabetes melitus tipe II merupakan suatu kondisi dimana gula darah mengalami kenaikan, yang disebabkan oleh sel β pankreas memproduksi insulin dalam jumlah sedikit dan juga adanya gangguan pada fungsi insulin. Edukasi merupakan salah satu pilar yang penting dalam penatalaksanaan pencegahan dan pengendalian diabetes melitus melalui manajemen diri. Tujuan penelitian ini yaitu untuk mengetahui pengaruh edukasi manajemen diri terhadap kualitas hidup pasien diabetes tipe II di Puskesmas Wonorejo Samarinda. Metode penelitian yaitu penelitian eksperimen semu yangdianalisis menggunakan statistik deskriptif dan uji Wilcoxon. Populasi dalam penelitian ini adalah pasien diabetes melitus tipe II di wilayah Wonorejo Samarinda pada bulan-Juni 2023 dengan jumlah sampel sebanyak 47 responden. Hasil penelitian menunjukan bahwa data karakteristik pasien diabetes melitus tipe 2 di wilayah kerja Puskesmas Wonorejo Samarinda paling banyak terjadi pada usia 55-65 (51%), jenis kelamin perempuan (77%), pendidikan terakhir SMA (55%) dan pekerjaan ibu rumah tangga (58%). Data pengaruh edukasi manajemen diri terhadap kualitas hidup responden yaitu terdapat pengaruh edukasi manajemen diri terhadap kualitas hidup pasien dengan nilai signifikan p = 0,000. Data pengaruh edukasi manajemen diri terhadap kadar gula darah puasa pasien yaitu terdapat pengaruh edukasi manajemen diri terhadap kadar gula darah puasa pasien dengan nilai signifikan p = 0,000. Type II diabetes mellitus is a condition where blood sugar rises due to pancreatic β-cells producing small amounts of insulin and also impaired insulin function. Education is one of the important pillars in management to prevent and control diabetes mellitus through self-management. The purpose of this study was to determine the effect of self-management education on the quality of life of type II diabetes patients at the Wonorejo Samarinda Health Center. The research method is a pseudoexperimental study analyzed using frequency distribution and Wilcoxon test. The population in this study were patients with type II diabetes mellitus at the Wonorejo Samarinda Health Center in June 2023 with a sample size of 47 respondents. The results of this study indicated that the data on the characteristics of patients with type 2 diabetes mellitus in the Wonorejo Samarinda Health Center working area are mostly age 55-65 (51%), female gender (77%), high school education (55%) and housewife work (58%). Data on the effect of self-management education on the quality of life of respondents showed that there was an effect of self-management education on the quality of life of patients with a significant value of p = 0.000. Data on the effect of self-management education on patient fasting blood sugar levels showed that there was an effect of self-management education on patient fasting blood sugar levels with a significant value of p = 0.000.
Pembuatan Simplisia Rimpang-rimpangan dan Dorongan Pembentukan Ukot Umot pada Kelompok Tani Desa Lempake Samarinda Sulistiarini, Riski; Nisaa, Nur Rezky Khairun; Farah, Harra Ismi; Arifian, Hanggara; Meylina, Lisna; Rijai, Akhmad Jaizzur; Prasesti, Gayuk Kalih
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 5, No 1 (2025): Abdira, Januari
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v5i1.568

Abstract

The community service activity themed "Preparation of Rhizome Simplisia and Encouragement for the Formation of Ukot Umot in the Farmer Group of Lempake Village, Samarinda" aimed to increase public knowledge about the preparation of high-quality rhizome simplisia and to encourage the establishment of local institution-based organizations (Ukot Umot). The activity involved farmer groups, women's PKK groups, and village officials. The materials presented included stages of washing, cutting, drying, and storing simplisia. Additionally, a participatory discussion on the importance of Ukot Umot institutions was conducted to strengthen collaboration and improve market access. Based on an evaluation through a questionnaire, 100% of participants stated that the activity was highly beneficial, with high satisfaction levels regarding the relevance of the material, the delivery method, and the benefits of the activity. The initial impacts of the activity included increased participant knowledge, a commitment to forming Ukot Umot, and motivation to process rhizomes independently. Despite challenges such as limited facilities, this activity successfully laid the foundation for the sustainable development of rhizome-based businesses.
Inovasi Pengolahan Buah Nipah Tua (Nypa fruticans) menjadi Tepung dan Nugget: Pemberdayaan Masyarakat Desa Salo Palai: Innovation in Processing Old Nypa (Nypa fruticans) Fruit into Flour and Nuggets: Empowering the Community of Salo Palai Village Wahyuni, Leny Eka Tyas; Pijaryani, Indria; Fadilla, Raisa; Anggreini, Putri; Siregar, Vita Olivia; Arief, Maryam Jamila; Nisaa, Nur Rezky Khairun
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 4 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i4.8523

Abstract

Old Nypa fruit (Nypa fruticans) often becomes waste in Salo Palai Village, East Kalimantan, due to a lack of knowledge regarding its utilization. Therefore, this activity aims to empower the community through training on processing old Nypa fruit into flour and nuggets, enhancing economic value, and reducing waste by utilizing local natural resources. The method consists of socialization by an expert speaker followed by a workshop on processing Nypa fruit. The activities were attended by members of the forest farmer group in Salo Palai Village. The outcome of this activity includes the production of Nypa fruit flour and nuggets made from Nypa flour. The results indicate that the residents of Salo Palai Village, particularly the members of the farmer group, are capable of applying information and technology related to processing aged Nypa fruit into flour and nuggets.
Skrining Fitokimia dan Studi Komparasi Kadar Flavonoid Dalam Bunga, Daun, dan Kulit Batang Pinus (Pinus merkusii) Nisaa, Nur Rezky Khairun; Wahyuni, Leny Eka Tyas; Anggreini, Putri
JUKEJ : Jurnal Kesehatan Jompa Vol 4 No 1 (2025): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol4.Iss1.1422

Abstract

Penelitian ini bertujuan untuk mengevaluasi kandungan flavonoid dan melakukan skrining fitokimia terhadap bunga, daun, dan kulit batang dari Pinus merkusii. Desain penelitian menggunakan pendekatan eksperimental laboratorium secara deskriptif dan komparatif. Sampel berupa bunga, daun, dan kulit batang pinus diperoleh secara purposive dari hutan pinus di wilayah X, dikeringkan dan diekstraksi menggunakan etanol 70%. Skrining fitokimia dilakukan dengan pereaksi spesifik untuk mendeteksi senyawa alkaloid, flavonoid, fenolik, saponin, steroid, dan terpenoid. Kadar flavonoid total dianalisis menggunakan spektrofotometri UV-Vis dengan metode AlCl₃ dan kurva standar kuersetin. Hasil menunjukkan bahwa ketiga bagian tanaman mengandung flavonoid dengan kadar rata-rata yang relatif rendah dan seragam, yaitu sebesar 0,043 mg QE/g. Senyawa fenolik dan alkaloid terdeteksi pada semua sampel, sementara steroid dan terpenoid tidak teridentifikasi. Kesimpulannya, bunga, daun, dan kulit batang Pinus merkusii memiliki potensi sebagai sumber antioksidan alami, namun untuk pengembangan lebih lanjut diperlukan isolasi senyawa aktif serta pengujian bioaktivitas spesifik
PEMBERDAYAAN KELOMPOK TP-PKK DESA ARGO MULYO, KECAMATAN SEPAKU, PENAJAM PASER UTARA MELALUI POJOK LITERASI TANAMAN OBAT KELUARGA (TOGA) Rozi, Fahrul; Siddiq, Muhammad Nuzul Azhim Ash; Anggreini, Putri; Kawareng, Andi Tenri; Wahyuni, Leny Eka Tyas; Nisaa, Nur Rezky Khairun; Majiding, Chaidir Masyhuri; Annisa, Oktavia Nasrul; Putra, Arya Yuliansyah; Aulia, Nasywa; Febriyanthy, Adhiesty Syaffila
Jurnal Abdi Insani Vol 11 No 4 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i4.2034

Abstract

Hypertension and hypercholesterolemia are common health problems in Argo Mulyo Village, Sepaku Sub-district, North Penajam Paser Regency. These diseases require a preventive approach through the utilization of family medicinal plants (TOGA) such as ginger, turmeric, and temulawak, which have been proven effective in reducing blood pressure and cholesterol levels. This empowerment activity aims to increase community knowledge, particularly among the TP-PKK group, regarding the use of TOGA as a preventive measure against hypertension and hypercholesterolemia. The activity was conducted on September 7-8, 2024, in Argo Mulyo Village. The methods used included education, training on the production of herbal powder from ginger, turmeric, and temulawak, and the planting of TOGA in the village land. Evaluation was carried out through pretest and posttest assessments to measure the participants' knowledge improvement. The results of the educational activity related to hypertension and hypercholesterolemia showed a significant increase in participants' knowledge, with an average pretest score of 60.23 rising to 76.51 in the posttest. The results of the herbal powder-making activity also showed an improvement in knowledge, with the pretest average score at 71.76 and 92.94 in the posttest. Additionally, the herbal powder products produced by the participants met the established standards. The planting of TOGA in the village land was also successfully implemented, indicating the success of this activity in raising community awareness and skills in utilizing local resources. In conclusion, this TOGA-based empowerment not only contributes to improving community health but also holds the potential to enhance economic welfare through herbal production.
Antioxidant Activity Test of Sappan (Caesalpinia sappan L.) and Chinese Teak (Senna alexandrina) Extract Combination Using DPPH (1,1 Diphenyl 2 Picrylhydrazyl) Free Radicals Scavenging Method Anisa, Rianti; Naid, Tadjuddin; Malik, Abd.; Nisaa, Nur Rezky Khairun
Jurnal Fitofarmaka Indonesia Vol 10, No 3 (2023): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v10i3.1103

Abstract

Sappan (Caesalpinia sappan L.) is applied as food and traditional medicine. Chinese teak (Senna alexandrina) is a plant from the tropics that can be developed as an antioxidant. This study was conducted to determine the antioxidant activity of the combination of Sappan and Chinese Teak by the DPPH (1,1 Diphenyl 2 Picrylhydrazyl) Free Radical Scavenging method. The extraction method used was maceration with Ethanol 96% as solvent. Determination of antioxidant levels was done quantitatively using the UV-Vis Spectrophotometer instrument at a wavelength of 514 nm. From the results of the study, the regression value obtained for the comparison of Quercetin is y = 3.1303x + 0.2292 with R2 = 0.9974 and IC50 value of 15.899 μg/mL. For the antioxidant activity of Sappan, the regression value y=0.5769x + 18.543 with R2=0.9969 and IC50 value of 54.53 μg/mL, Chinese Teak obtained regression value y=0.1421x + 17.506 with R2=0.9989 and IC50 value of 228.67 μg/mL, and for the combination obtained regression value y=0.4304x + 36.622 with R2=0.9954 and IC50 value of 40.38 μg/mL. The results of this study indicate that the combination of Sappan and Chinese Teak extracts has a very strong antioxidant effect (<50 μg/mL).
EDUKASI LIMBAH MAKANAN, BAHAYA TERHADAP KESEHATAN DAN LINGKUNGAN SERTA POTENSI PEMANFAATANNYA UNTUK MENGURANGI FOOD WASTE Muhammad Nuzul Azhim Ash Siddiq; Pakki, Irfansyah Baharuddin; Junaidin, Junaidin; Sinthary, Venna; Rozi, Fahrul; Majiding, Chaidir Masyhuri; Wahyuni, Leny Eka Tyas; Nisaa, Nur Rezky Khairun; Anggreini, Putri; Wirawanti, Ika Wirya; Khuzaimah, Ummi; Rahmadani, Aulia Tia; Sari, Mila Warma
Jurnal Abdi Insani Vol 11 No 3 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i3.1928

Abstract

Bukit Merdeka Village has great potential for the development of pineapple commodities; however, the utilization of pineapple peel waste remains suboptimal and is often regarded as mere waste. The management of food waste has become a critical issue due to its negative impact on health and the environment, where food waste is often discarded without further utilization. The objective of this community service activity is to educate the public about the dangers and potential benefits of food waste, with the hope of reducing waste, increasing economic welfare through innovation, and encouraging the people of Bukit Merdeka Village to better understand and optimize the use of food waste creatively and productively. This activity was conducted through lectures and interactive discussions involving all members of the PKK in Bukit Merdeka Village. Participants were also asked to take pre-tests and post-tests to measure their understanding before and after the education. There was a significant increase in the post-test results compared to the pre-test, with the average score of participants rising from 56.0 ± 3.2 to 84.6 ± 1.7. These results indicate that the education provided successfully improved participants' understanding of the dangers of food waste and how to utilize it. This educational activity successfully raised awareness and improved community skills in managing food waste, as well as opened economic opportunities through the utilization of pineapple peel waste.
Comparative study of vitamin c content in rome Beauty apples (malus sylvestris mill) with several Processing methods Wahyuni, Leny Eka Tyas; Furkon, Leily Amalia; Safika, Erri Larene; Nisaa, Nur Rezky Khairun
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background : Apples are known to contain antioxidants and vitamin C, which play important roles in protecting the body from oxidative stress and degenerative diseases. However, vitamin C is sensitive to heat, light, and oxygen, which can lead to degradation during processing. Objective : This study aimed to compare the vitamin C content of Rome Beauty apple (Malus sylvestris Mill) in various processed forms commonly consumed by the public, including fresh apple, apple juice, cider, dodol, and apple chips. Research Methods/ Implementation Methods : The research was conducted using a titrimetric method with 2,6-dichlorophenol-indophenol dye to determine vitamin C content. Five samples were analyzed in duplicate. The data were statistically tested using the Kruskal–Wallis and Mann–Whitney tests to evaluate differences among samples. Results : The vitamin C content ranged from 2.85 to 12.36 mg/100 g. The highest content was found in fresh apples (12.36 mg/100 g), followed by apple juice (6.41 mg/100 g), apple extract (5.23 mg/100 g), apple dodol (2.85 mg/100 g), and apple chips (2.85 mg/100 g). Statistical analysis showed significant differences (p < 0.05) among the samples, particularly between fresh or juiced apples and processed forms such as dodol and chips. Conclusion/Lesson Learned : Processing significantly reduces the vitamin C content of Rome Beauty apples. Heat treatment, oxidation, and exposure to air during processing are the major factors contributing to vitamin C loss. Therefore, consuming fresh apples provides the greatest nutritional benefit in terms of vitamin C intake.
PEMBERDAYAAN KELOMPOK WANITA TANI NUSA INDAH MELALUI PENGEMBANGAN KEBUN KELOR DAN DIVERSIFIKASI PRODUK OLAHAN KELOR Masyhuri Majiding, Chaidir; Rozi, Fahrul; Nisaa, Nur Rezky Khairun
Jurnal Abdi Insani Vol 12 No 10 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i10.3044

Abstract

Moringa oleifera is a nutrient-rich plant with potential as a functional food and a source of household income. The Nusa Indah Women Farmers’ Group (KWT) has access to moringa resources but faces challenges such as limited knowledge, skills, and the absence of a standardized moringa garden. Consequently, their products have been restricted to sticks and herbal tea, leaving economic value underutilized. Empowerment through training and product diversification was therefore introduced as a strategic solution. This program aimed to enhance the knowledge and skills of KWT Nusa Indah in developing moringa gardens and producing diversified products such as biscuits, dried noodles, and herbal soap. The method included establishing a moringa garden using planter bags, applying compost fertilizer, and conducting training with hands-on product processing. Knowledge was evaluated through pretest and posttest, while skills were assessed by direct observation. The results showed the establishment of a moringa garden with 20 well-maintained plants and the successful production of moringa-based biscuits, noodles, and soap. The mean pretest score of 62.40 increased to 90 in the posttest, with a Wilcoxon test confirming significant improvement (p=0.000). This indicates a 27.6% increase in knowledge. Participants also demonstrated enhanced skills through the ability to produce standardized products. In conclusion, the empowerment program effectively improved knowledge, skills, and productivity of KWT Nusa Indah, while promoting sustainable utilization of moringa as both a nutritional resource and an economic opportunity. Keywords: empowerment, moringa garden, product diversification, women farmers’ group
Co-Authors ABD. MALIK Andi Tenri Kawareng Anggreini, Putri Ani Isnawati Anisa, Rianti Annisa, Oktavia Nasrul Arief, Maryam Jamila Arifian, Hanggara Aulia, Nasywa Bafadal, Mentarry Fadilla, Raisa Fahrul Rozi Farah, Harra Ismi Febriyanthy, Adhiesty Syaffila Furkon, Leily Amalia Hajrah Irfansyah Baharuddin Pakki Junaidin, Junaidin Lucie Widowati Maesa, Beki Majiding, Chaidir Masyhuri Masyhuri Majiding, Chaidir Meylina, Lisna Muhammad Nuzul Azhim Ash Siddiq Mus, Nurul Muhlisa Pijaryani, Indria Prasesti, Gayuk Kalih Prasetya, Fajar Putra, Arya Yuliansyah Rahmadani, Aulia Tia Rijai, Akhmad Jaizzur Safika, Erri Larene Sari, Mila Warma Siddiq, Muhammad Nuzul Azhim Ash Sinthary, Venna Siregar, Vita Olivia Sulistiarini, Riski Tadjuddin Naid Ummi Khuzaimah Wahyuni, Leny Eka Tyas Wirawanti, Ika Wirya