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All Journal Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains
Juwita, Nur Aira
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Agriculture, Biological Sciences & Forestry Education Law, Crime, Criminology & Criminal Justice Social Sciences

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Analisis Network Pharmacology Senyawa Metabolit Sekunder Tumbuhan Benalu Kopi (Loranthus ferrugineus Roxb.ex Jack Danser) pada Penyakit Kanker Payudara Juwita, Nur Aira; Sujarwo, Wawan; Rizka Manurung, Dinda
BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains Vol. 8 No. 4 (2025): Bioedusains: Jurnal Pendidikan Biologi dan Sains
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/gz2pdd34

Abstract

This study aims to evaluate the potential of coffee bean metabolite compounds as breast anticancer agents through a network pharmacology approach. The method used starts from literature study and PubChem database. Selection of compound eligibility was carried out with SwissADME using Lipinski's Rule of Five criteria. Protein target prediction was done through SwissTargetPrediction, while breast cancer target data was obtained from GeneCards and OMIM. Protein-protein interactions were analyzed with STRING and visualized using Cytoscape. Compound-protein interactions were analyzed through STITCH. The results showed that nine metabolite compounds from coffee bean met the pharmacokinetic criteria, with five main compounds showing anticancer potential is quercetin, oleic acid, linoleic acid, GCG, and PPARA. Protein interaction network analysis identified five central target proteins: IL6, TNF, AKT1, PTGS2, and ESR1. The compound-protein interactions suggest multitarget potential in the modulation of breast cancer-related molecular pathways. Keywords: Breast Cancer, Loranthus ferrugineus, Network Pharmacology
Training on Manufacture of Processed Cassava to Improve the Economy in Serasi Jaya Farmer Group Reveny, Julia; Masfria; Syahputra, Hafid; Juwita, Nur Aira; Rohani, Ade Sri
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 1 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i1.9525

Abstract

Cassava (Manihot utilissima) is a local food commodity that is widely cultivated in Indonesia. The advantages of this plant are rich in carbohydrates, long harvest range, capable of producing in less fertile or infertile soils. However, cassava peel waste is still rarely processed into more useful products. Therefore, it is necessary to make efforts to increase the utilization of cassava peels into innovative products by conducting counseling and training in the manufacture of processed body scrubs with cassava peels as a base material to utilize regional natural resources into products with higher economic value, especially in the Serasi Jaya Village Farmer Group. The people's glare is located in Sei Rampah District, Serdang Bedagai Regency, North Sumatra. The method of service activities is carried out by lectures and demonstrations/training. The results of this activity were very satisfying because participants were able to make and use cassava peels into innovative products, namely body scrubs which were useful as skin care cosmetics so that they could help improve the community's economy
Training and Hedonic Survey Test of Lemon Candy Using Natural Sweetener from Sugarcane Water as an Odors Fadhillah, Nurul; Surbakti, Chemayanti; Lubis, Muhammad Fauzan; Juwita, Nur Aira
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 2 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i2.10841

Abstract

Lemon candy is a candy that has a combination of sweet and sour taste. In making lemon candy using several ingredients. One of them is using natural ingredients. Plants that can be used as ingredients for making candy are lemon juice and sugarcane juice. This community service activity involved class XI HKBP Sidorame Private High School students which was based on product innovation in the form of lemon candy with a combination of the two natural ingredients above. The purpose of this activity is to determine the level of preference (hedonic) for a product in the form of lemon candy with a combination of lemon juice and sugarcane juice. The activity begins with making a product in the form of lemon candy from a combination of lemon juice and sugarcane juice. The activity continued with data collection using pre-test, post-test and hedonic test questionnaires. The results of filling out the pre-test showed that SMAS HKBP Sidorame students' knowledge regarding lemon candy was still lacking with the percentage of yes answers to each question namely 100%, 33.33%, 20%, 6.67%, 40%. The results of filling out the post-test showed that SMAS HKBP students' knowledge was very good with the percentage of yes answers to each question namely 100%, 77%, 97%, 93%, 93%. This shows the development and increase in knowledge of SMAS HKBP Sidorame students about lemon candy. The results of the hedonic test survey obtained the highest percentage for shape parameters of 33.33% (very like), color of 43.3% (quite like), aroma of 40% (like very much), hardness of 30% (very like) and taste of 46.67% (very like). These results indicate that SMAS HKBP Sidorame students like the preparation of lemon candy.
Training and Hedonic Survey Tests of Herbal Bath Salt Products with a Combination of Jeringau and Lemon Peel as a Body Relaxant Utami, Nurhafizah; Surbakti, Chemayanti; Lubis, Muhammad Fauzan; Juwita, Nur Aira
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 2 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i2.10899

Abstract

Bath salt or better known as bath salt is a product that has recently been growing rapidly. Herbal bath salt itself is still not widely developed by the community. Herbal bath salts can be made from ginger powder and lemon peel which has a distinctive fragrance that can be relaxing for anyone who uses it. This community service activity involved class XI HKBP Sidorame Private High School students based on an innovative herbal bath salt preparation with a combination of ginger and lemon peel. The purpose of this activity is to determine the level of preference (hedonic) for a combination of lemon peel and ginger bath salt preparations. The activity began with the preparation of a combination of lemon peel and ginger bath salt. The activity ended with data collection using pre-test, post-test and hedonic test questionnaires. The results of filling out the pre-test showed that SMAS HKBP Sidorame students' knowledge was still lacking with the proportions for each question namely 23,33%, 6,66%, 10%, 0% and 30%. The results of filling out the post-test showed that the students' knowledge of SMAS HKBP was very good with a proportion of 100% for each question. This shows the development and increase in knowledge of SMAS HKBP Sidorame students about bath salts. The results of the hedonic test survey obtained the largest proportion for shape parameters of 56,66% (very like), color of 50% (like very much), fragrance of 70% (very like), hardness of 46,66% (very like) and ease of use of 63,33% (very like). These results indicate that SMAS HKBP Sidorame students like bath salt product.
Co-Authors Fadhillah, Nurul Hafid Syahputra Julia Reveny lubis, muhammad fauzan Masfria Rizka Manurung, Dinda Rohani, Ade Sri Surbakti, Chemayanti Utami, Nurhafizah Wawan Sujarwo