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All Journal Sewagati: Jurnal Pengabdian Masyarakat Indonesia Parapemikir Jurnal Ilmiah Farmasi Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Wulandari, Anggita Dipika
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Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Optimasi Pembuatan dan Karakterisasi Ukuran Partikel Superparamagnetic Iron Oxyde Nanoparticles Wulandari, Anggita Dipika; Yusuf, Mubarika Sekarsari; Husniyah, Laelatul
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 2 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i2.8716

Abstract

Superparamagnetic Iron Oxide Nanoparticles (SPION) are iron-based nanoparticles gaining attention in the medical field due to their ability to be magnetically guided and their biocompatibility. This study aimed to explore how different homogenization speeds affect the size, distribution, and stability of SPION synthesized through the co-precipitation method. Three formulations were prepared using homogenization speeds of 1000 rpm, 3000 rpm, and 6000 rpm. The resulting particles were analyzed using Dynamic Light Scattering (DLS) to determine particle size, polydispersity index (PDI), and zeta potential. The results showed that Formula 2 (3000 rpm) produced the smallest and most evenly distributed particles (305,2 nm) with good stability. Formula 3 (6000 rpm) had a higher zeta potential, its particle size was larger and distribution less uniform. Formula 1 (1000 rpm) yielded large but more uniformly distributed particles. The results of this study show moderate homogenization speed offers the best conditions for producing SPION that are small, stable, and suitable for biomedical applications. Formula 2 shows the most promise for future development in drug delivery or magnetic hyperthermia therapies
Pelatihan Pembuatan Lotion Anti Nyamuk Herbal Kombinasi Daun Sereh dan Daun Pandan sebagai Upaya Perlindungan terhadap Gigitan Nyamuk pada PKK di Kelurahan Sukorejo, Kota Semarang Anggita Dipika Wulandari; Rifda Naufa Lina; Rahmawati Salsa Dinurrosifa
SEWAGATI: Jurnal Pengabdian Masyarakat Indonesia Vol. 4 No. 3 (2025): September : Jurnal Pengabdian Masyarakat Indonesia
Publisher : BADAN PENERBIT STIEPARI PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56910/sewagati.v4i3.3107

Abstract

The rainy season in Sukorejo Village, Semarang City, increases mosquito populations due to stagnant water, potentially transmitting diseases such as dengue fever, malaria, and chikungunya. The community still relies on chemical-based mosquito repellent lotions containing DEET, which carry risks of skin irritation, allergies, and potential toxicity. Natural ingredients such as lemongrass (Cymbopogon nardus) and pandan leaves (Pandanus amaryllifolius) contain active compounds—citronellal, geraniol, alkaloids, flavonoids, and polyphenols—that are effective as natural repellents. The purpose of this activity is to enhance the knowledge and skills of PKK women in utilizing lemongrass and pandan leaves for the production of safe, effective, and environmentally friendly herbal mosquito repellent lotion. The program was implemented in four stages: (1) health education on mosquito-borne diseases and active plant compounds, (2) training on herbal lotion production covering raw material selection, hygienic processing, formulation, and packaging, and (3) production assistance by the community service team. Methods included lectures, discussions, demonstrations, and hands-on practice. The program improved participants’ understanding of natural repellents and their ability to independently produce herbal lotion. The lemongrass–pandan lotion produced met safety standards, had a pleasant aroma, and was effective in protecting against mosquito bites. This training effectively increased the capacity of PKK members, reduced dependency on commercial chemical-based products, and opened opportunities for local, small-scale businesses.
Senyawa Metabolit Sekunder pada Daun Kelengkeng dan Daun Jeruk Limau yang Berkhasiat sebagai Obat Tradisional Rifda Naufa Lina; Anggita Dipika Wulandari; Laelatul Husniyah
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 3 (2025): November : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i3.8041

Abstract

Public interest in natural remedies has increased significantly in recent years, leading to a growing reliance on traditional medicinal plants as alternative or complementary therapies. Among the plants widely used across generations in various cultural practices are longan leaves (Euphoria longan (Lour.) Steud) and kaffir lime leaves (Citrus amblycarpa (Hassk.) Ochse). Both are believed to possess a variety of health-promoting properties and have long been utilized in traditional medicine for their therapeutic potential. Despite their popularity, scientific investigations that specifically explore their phytochemical composition and pharmacological activities remain limited. This study was therefore conducted to examine the secondary metabolite content of both plants and to evaluate their potential as sources of bioactive compounds. The extraction process was carried out using the maceration technique with 96% ethanol as a solvent, followed by a series of phytochemical screening tests. The analysis aimed to identify the presence of key classes of secondary metabolites such as flavonoids, alkaloids, tannins, saponins, terpenoids, and steroids, which are known to contribute to various biological activities including antioxidant, anti-inflammatory, antimicrobial, and hepatoprotective effects. The results revealed that both longan and kaffir lime leaves tested positive for all targeted secondary metabolite groups. The consistent presence of flavonoids, alkaloids, tannins, saponins, terpenoids, and steroids suggests that these plants hold considerable pharmacological promise. Their metabolite profiles align with the reported therapeutic uses of these leaves in traditional medicine, providing scientific support for their continued application as herbal remedies. Overall, this research strengthens the understanding of Euphoria longan and Citrus amblycarpa as potential sources of phytopharmaceuticals. The findings not only validate their traditional medicinal uses but also highlight their potential in the development of natural-based drug formulations. Further in-depth studies, including isolation of active compounds and pharmacological assays, are recommended to fully characterize their therapeutic properties and clinical applications.
Evaluasi Fisik Sediaan Tablet Amlodipine (Besilat) sebagai Obat Antihipertensi: Perbandingan antara Tablet Generik dan Generik Bermerek Laelatul Husniyah; Anggita Dipika Wulandari; Hafidz Muzaki
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 4 No. 2 (2025): Mei : Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v4i2.4060

Abstract

Popular antihypertensive drugs used are amlodipine (besylate) in generic and branded generic tablets. To ensure that a drug is of good quality and efficacy, evaluation of the physical quality of the tablet is very important. This study aims to determine the results of the physical evaluation of generic and branded amlodipine (besylate) tablets that are currently available for purchase. This type of experimental study involves random sample selection. Testing was carried out on three samples of generic amlodipine (besylate) tablets and one sample of branded generic tablets. The physical evaluation of the tablets carried out was uniformity of weight, uniformity of size, hardness, friability, and disintegration time as part of the physical examination. The test results showed that generic tablets 3 and branded generics met the requirements of the Indonesian Pharmacopoeia.    
Co-Authors Hafidz Muzaki Husniyah, Laelatul Laelatul Husniyah Rahmawati Salsa Dinurrosifa Rifda Naufa Lina Yusuf, Mubarika Sekarsari