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Antiemetic prophylaxis utilization in cancer patients in a hospital in Yogyakarta Special Region Faridah, Imaniar Noor; Dyah Aryani Perwitasari; Siswandi; Lamhot B Simanjuntak; Suhendra, Gugun; Wulandari, Dewi; Dania, Haafizah; Rizky, Muhammad Arif; Islami, Safira Nur; Fatimah, Salma Auliya
Indonesian Journal of Pharmacology and Therapy Vol 5 No 3 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.14243

Abstract

Chemotherapy is a type cancer treatment that uses anticancer drugs to inhibit cell division and kill cancer cells. Chemotherapy can cause side effect due to normal cells damages. The study aimed to investigate the use of antiemetic prophylaxis as premedication to prevent or reduce side effects on cancer patients undergoing chemotherapy. It was a observational study with retrospective design using medical records data of cancer patients who underwent chemotherapy in a hospital in Yogyakarta Special Region during May – September 2022. The results showed the cancer patients were dominated by women (85.71%) with ages 46-65 yr (63.27%) and stage III cancer (87.76%). There were 18 types of anticancer drugs and the most widely used drugs were doxorubicin 60 mg for the moderate emetogenic category and vinorelbine 37.5 mg for the low emetogenic category. The most widely used premedication regimen was a combination granisetron 3 mg, ondansetron 8 mg, and dexamethasone 10 mg regimen (72.45%). This combination was most often used for the cancer patients with the moderate emetogenic category (39 patients or 49.4%). However, not all the cancer patients undergoing chemotherapy with the low and moderate emetogenic anticancer drugs were administered the premedication. In conclusion, doxorubicin and vinorelbine are the most widely used for cancer patients undergoing chemotherapy in the hospital. In addition, a combination of granisetron, ondansetron, and dexamethasone is widely used as premedication.
The quality of life of hemodialysis patients in Yogyakarta, Indonesia Siswandi, Siswandi; Perwitasari, Dyah Aryani; B Simanjuntak, Lamhot; Suhendra, Gugun; Wulandari, Dewi; Dania, Haafizah; Faridah, Imaniar Noor; Adnan, Adnan
Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.28449

Abstract

The assessment of quality of life serves as a critical evaluation of the effectiveness of the administered hemodialysis treatment. The measurement of quality of life can be conducted using the Kidney Disease Quality of Life Short Form (KDQoL-SF™) questionnaire. This research aims to gather information concerning the quality of life among patients with hemodialysis due to chronic kidney failure at the dr. S. Hardjolukito Regional Military Hospital in Yogyakarta. The research employed a cross-sectional design. The respondents consisted of 65 patients selected through purposive sampling based on specific inclusion and exclusion criteria. The Independent T-test, Mann-Whitney test, Chi-Square test and Fischer test were conducted to define the association between quality of life and respondent characteristics. Most of the hemodialysis patients was male (50.8%) with average od age was 54.66 years old. The findings revealed that 64.6% of the respondents experienced moderate/poor quality of life, while 35.4% exhibited good quality of life. Statistical analysis established a significant relationship between respondent characteristics and quality of life based on the variables of age and duration of hemodialysis (p<0.05). Hemoglobin levels, number of prescribed medications, gender, education, occupation and income demonstrated no significant relationship with the quality of life. Among the respondents’ characteristics, age and duration of hemodialysis were associated with the quality of life.
Nutritional Status and Quality of Life of Hemodialysis Patients in a Hospital in Yogyakarta Siswandi, Siswandi; Suhendra, Gugun; Wulandari, D; Simanjuntak, LB; Dania, Haafizah; Irham, Lalu Muhammad; Faridah, Imaniar; Adnan, Adnan; Perwitasari, Dyah Aryani
Pharmacon: Jurnal Farmasi Indonesia Vol 20, No 2 (2023)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v20i2.23313

Abstract

Kidney failure is a disease with a moderate prevalence in Indonesia but causes the second highest cost burden in Indonesia. One of the treatments for chronic kidney failure is hemodialysis. The problem with hemodialysis patients is a high incidence of malnutrition, which can affect the patient's quality of life. Therefore, this study will examine the relationship between nutritional status and quality of life in chronic kidney failure patients undergoing hemodialysis. This research is a cross-sectional study by collecting medical record data and filling out questionnaires. Selection of research subjects with inclusion criteria aged ≥18 years, routinely undergoing hemodialysis, willing to participate in the study and complete medical record data. The patient's nutritional status was seen from the Body Mass Index (BMI), and the patient's quality of life was assessed by the Indonesian version of the Kidney Disease Quality of Life Short-Form (KDQoL-SFTM) questionnaire. The average age of the hemodialysis patients in this study was 53.70 years, the average body weight was 57.24 kg and the average height was 10.82 cm. Patients with lean BMI were 20.5%, normal 56.4%, overweight 23.1%, and obesity 2.6%. The domain of employment status is related to nutritional status (p-value 0.005). Nutritional status is related to the quality of life of hemodialysis patients in the occupational status domain.