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All Journal BioEksakta : Jurnal Ilmiah Biologi Unsoed Journal of Medicine and Health Technology
Aprilia, Veranita
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Veterinary

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Pengaruh Perbedaan Konsentrasi Nacl pada Pertumbuhan Varietas Padi Logawa, Situ Bagendit, dan Inpari Secara In Vitro Rosyid Ridho, Muhammad Ainur; Aprilia, Veranita; Irwandi, Shafannisa Febrina; Helan, Maria Elfiana Ina Kewa
BioEksakta : Jurnal Ilmiah Biologi Unsoed Vol 7 No 3 (2025): BioEksakta
Publisher : Fakultas Biologi Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.bioe.2025.7.3.15581

Abstract

Studi ini menyelidiki pengaruh konsentrasi natrium klorida (NaCl) terhadap pertumbuhan tiga varietas padi: Logawa, Situ Bagendit, dan Inpari, menggunakan kultur in vitro. Media kultur disiapkan dengan konsentrasi NaCl bervariasi (150 mM, 250 mM, dan 255 mM) dan parameter pertumbuhan diukur, termasuk panjang dan jumlah daun, panjang dan jumlah akar, berat segar, kandungan klorofil, dan tinggi total tanaman. Hasil menunjukkan bahwa varietas Logawa memiliki toleransi tertinggi terhadap stres salinitas, dengan pertumbuhan yang lebih baik dibandingkan Situ Bagendit dan Inpari. Peningkatan konsentrasi NaCl menyebabkan penurunan kandungan klorofil dan berat segar pada semua varietas, mengindikasikan dampak negatif salinitas terhadap efisiensi fotosintesis dan kesehatan tanaman.
Exploring the Phytochemistry and Pharmacological Potentials of Annona squamosa L. : A Systematic Review of Traditional Uses and Modern Applications Rosyid Ridho, Muhammad Ainur; Indriani, Ratri Dwi; Wulansari, Arfiana Tanti; Purwani, Kristanti Indah; Nurhidayati, Tutik; Trisnawati, Indah; Aprilia, Veranita; Pradani, Anindhita Nabilah; Putra, Roy Ardiansyah; Lekatompessy, Vanela Chatrin
Journal of Medicine and Health Technology Vol. 2 No. 2 (2025)
Publisher : Direktorat Riset dan Pengabdian Kepada Masyarakat, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j30466865.v2i2.4287

Abstract

Annona squamosa L. (Annonaceae) is a tropical evergreen fruit tree with a long history of traditional use across various cultures. Its fruit, known as srikayas, is commonly consumed fresh and used in candies, ice creams, and beverages. Different parts of A. squamosa have been widely applied in ethnomedicine as tonics, apophlegmatisants, coolants, abortifacients, and heart sedatives. Phytochemical studies have identified key bioactive compounds including annonaceous acetogenins (ACGs), diterpenes (DITs), alkaloids (ALKs), and cyclopeptides (CPs), with 33 diterpenes, 19 alkaloids, 88 acetogenins, and 13 cyclopeptides reported up to 2016. Extensive research reveals A. squamosa exhibits diverse pharmacological activities such as anticancer, antioxidant, antidiabetic, antihypertensive, hepatoprotective, antiparasitic, antimalarial, insecticidal, microbicidal, and molluscicidal effects. Notably, diterpenes and acetogenins contribute to its potent anticancer properties through apoptosis induction and cell cycle arrest. Leaf and seed extracts demonstrate significant antidiabetic, anti-inflammatory, and hepatoprotective actions, while seed peptides exhibit vasorelaxant and hypotensive effects via calcium channel inhibition. This review integrates phytochemical, ethnopharmacological, and bioactivity data, highlighting the therapeutic potential of A. squamosa and encouraging further clinical studies to validate its medicinal applications.
Phytochemical Constituents and Therapeutic Potential of Pine Bark and Needle Extracts in Cardiovascular and Metabolic Disorders Rosyid Ridho, Muhammad Ainur; Indriani, Ratri Dwi; Wulansari, Arfiana Tanti; Purwani, Kristanti Indah; Nurhidayati, Tutik; Aprilia, Veranita; Pradani, Anindhita Nabilah; Putra, Roy Ardiansyah; Farid, Ardiansyah
Journal of Medicine and Health Technology Vol. 3 No. 1 (2026)
Publisher : Direktorat Riset dan Pengabdian Kepada Masyarakat, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j30466865.v3i1.4288

Abstract

Cardiovascular and metabolic diseases remain leading global health challenges, necessitating novel and complementary therapeutic strategies. Natural plant-derived compounds, particularly from pine bark and needles, have attracted attention for their potential health benefits. This study aims to comprehensively review the phytochemical composition of pine bark and needle extracts, focusing on their biological activities and potential roles in preventing and managing cardiovascular and metabolic disorders. A literature review was conducted using databases such as PubMed, ScienceDirect, and Google Scholar, focusing on studies published from 2000 to 2024. The selection criteria included in vitro, in vivo, and clinical research articles investigating the phytochemical profiles and pharmacological effects of pine bark and needle extracts on cardiovascular and metabolic health. Pine bark and needle extracts, especially from Pinus pinaster, are rich in proanthocyanidins, flavonoids, phenolic acids, stilbenes, and terpenoids. These bioactive compounds exhibit potent antioxidant, anti-inflammatory, and endothelial protective properties. Clinical and preclinical studies demonstrate improvements in blood pressure, lipid profiles, glucose metabolism, and vascular function. Emerging evidence also suggests a role in modulating gut microbiota, contributing to systemic metabolic benefits. Pine bark and needle extracts hold significant promise as adjunct therapies for cardiovascular and metabolic diseases through their multi-targeted mechanisms. Further well-designed clinical trials are necessary to validate their efficacy, optimize dosages, and ensure safety for broader therapeutic application.
Co-Authors Farid, Ardiansyah Helan, Maria Elfiana Ina Kewa Indriani, Ratri Dwi Irwandi, Shafannisa Febrina Kristanti Indah Purwani Lekatompessy, Vanela Chatrin Pradani, Anindhita Nabilah Putra, Roy Ardiansyah Rosyid Ridho, Muhammad Ainur Trisnawati, Indah Tutik Nurhidayati Wulansari, Arfiana Tanti