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All Journal BioEksakta : Jurnal Ilmiah Biologi Unsoed JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Rumphius Pattimura Biological Journal Journal of Medicine and Health Technology
Rosyid Ridho, Muhammad Ainur
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Veterinary

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The The Potential of Curcuma longa as an Antidiabetic Agent: Review: The Potential of Curcuma longa as an Antidiabetic Agent: Review Rosyid Ridho, Muhammad Ainur; Indriani, Ratri Dwi
Journal of Medicine and Health Technology Vol. 2 No. 1 (2025)
Publisher : Direktorat Riset dan Pengabdian Kepada Masyarakat, Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j30466865.v2i1.2383

Abstract

Diabetes mellitus (DM) is a chronic metabolic disease characterized by persistently elevated blood sugar levels due to impaired insulin action or production. It is a global health concern, contributing to various complications such as retinopathy, neuropathy, and cardiovascular diseases. While antidiabetic medications have improved treatment options, challenges such as adverse effects, resistance, and high costs have fueled the interest in exploring natural alternatives, including Curcuma longa, commonly known as turmeric. This review aims to evaluate the potential of Curcuma longa as an antidiabetic agent by synthesizing data from existing literature. A systematic search of databases including PubMed, Scopus, Web of Science, and Google Scholar was conducted, focusing on studies from 2000 to 2024 that examined the pharmacological effects, mechanisms of action, and clinical applications of Curcuma longa in diabetes. The review highlights that curcumin, the active compound in Curcuma longa, significantly reduces blood glucose levels, improves insulin sensitivity, and exhibits anti-inflammatory and antioxidant properties. Curcumin acts through multiple mechanisms, including the modulation of glucose transporters, activation of AMPK, reduction of oxidative stress, and inhibition of inflammatory cytokines. Preclinical and clinical studies demonstrate that curcumin can improve glycemic control, reduce insulin resistance, and prevent diabetes-related complications. Despite promising results, further clinical trials are needed to confirm its therapeutic potential. This review underscores the potential of Curcuma longa as a natural adjunct or alternative to conventional antidiabetic therapies.
Ethnopharmacy and Traditional Knowledge Study with a Family Use Value Approach in Sumberbrantas Village, Bumiaji District, Batu City, East Java Rosyid Ridho, Muhammad Ainur; Trisnawati, Indah; Nurhidayati, Tutik; Purwani, Kristanti Indah; Saptarini, Dian; Kuswytasari, Nengah Dwianita
RUMPHIUS Vol 7 No 2 (2025): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/rumphiusv7i2p088-100

Abstract

Indonesia is recognized as one of the world’s most biodiverse countries, with an estimated 17% of global plant and animal species found within its borders. This biodiversity supports a wealth of medicinal plants that have been traditionally utilized by local communities. However, rapid modernization has led to a decline in the transmission of ethnobotanical knowledge. This study investigates the ethnopharmacological practices in Sumberbrantas Village, Bumiaji District, Batu City, East Java, with a focus on the Family Use Value (FUV) approach to identify the most utilized plant families in traditional medicine. Data were collected through structured interviews with 70 respondents selected using purposive and snowball sampling techniques. The study analyzed the FUV and Fidelity Level (FL) of various plant species to determine their significance in traditional healing practices. Results indicate that the Zingiberaceae and Euphorbiaceae families have the highest FUV (0.45), highlighting their widespread use in treating various ailments. Conversely, the Oxalidaceae family exhibits the lowest FUV (0.01). The FL analysis shows that Allium cepa (shallot) has the highest fidelity level (75%), demonstrating its prominence in treating multiple conditions. This research provides critical insights into the preservation of ethnomedicinal knowledge and the sustainable use of medicinal plant resources. The findings serve as a valuable reference for conservation efforts and the development of community-based herbal medicine initiatives.
Pengaruh Perbedaan Konsentrasi Nacl pada Pertumbuhan Varietas Padi Logawa, Situ Bagendit, dan Inpari Secara In Vitro Rosyid Ridho, Muhammad Ainur; Aprilia, Veranita; Irwandi, Shafannisa Febrina; Helan, Maria Elfiana Ina Kewa
BioEksakta : Jurnal Ilmiah Biologi Unsoed Vol 7 No 3 (2025): BioEksakta
Publisher : Fakultas Biologi Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.bioe.2025.7.3.15581

Abstract

Studi ini menyelidiki pengaruh konsentrasi natrium klorida (NaCl) terhadap pertumbuhan tiga varietas padi: Logawa, Situ Bagendit, dan Inpari, menggunakan kultur in vitro. Media kultur disiapkan dengan konsentrasi NaCl bervariasi (150 mM, 250 mM, dan 255 mM) dan parameter pertumbuhan diukur, termasuk panjang dan jumlah daun, panjang dan jumlah akar, berat segar, kandungan klorofil, dan tinggi total tanaman. Hasil menunjukkan bahwa varietas Logawa memiliki toleransi tertinggi terhadap stres salinitas, dengan pertumbuhan yang lebih baik dibandingkan Situ Bagendit dan Inpari. Peningkatan konsentrasi NaCl menyebabkan penurunan kandungan klorofil dan berat segar pada semua varietas, mengindikasikan dampak negatif salinitas terhadap efisiensi fotosintesis dan kesehatan tanaman.
Bibliometric Analysis of Global Research Trends on the Antidiabetic Potential of Andaliman (Zanthoxylum armatum DC.) Rosyid Ridho, Muhammad Ainur; Indriani, Ratri Dwi; Hidayanti, Restu
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 4 No. 2 (2025): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v4i2.4279

Abstract

This study presents a bibliometric analysis of global research trends concerning the antidiabetic potential of Zanthoxylum armatum DC. Data were retrieved from the Scopus database and analyzed using VOSviewer to map keywords, thematic clusters, and research evolution. The findings highlight a strong focus on antidiabetic effects and the pharmacological activity of bioactive compounds such as alkylamides, flavonoids, and phenolics, which act through mechanisms including inhibition of α-glucosidase and α-amylase, activation of the AMPK pathway, and enhancement of glucose transport. The visualizations also reveal the incorporation of Z. armatum into low-glycemic functional foods. This study underscores the plant’s promising role in natural diabetes therapy and the value of bibliometric approaches in systematically evaluating research landscapes.
Co-Authors Aprilia, Veranita Dian Saptarini Helan, Maria Elfiana Ina Kewa Hidayanti, Restu Indriani, Ratri Dwi Irwandi, Shafannisa Febrina Kristanti Indah Purwani Nengah Dwianita Kuswytasari Trisnawati, Indah Tutik Nurhidayati