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All Journal Jurnal Biologi Tropis JURNAL BIOSHELL
Rahmawati, Ayu Sintya Citra
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology

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Hubungan Pengetahuan dan Kepatuhan Cuci Tangan terhadap Kejadian Demam Tifoid di Kabupaten Tulungagung Nurjanah, Mutia Hariani; Wijaya, Anas Fadli; Fuzianingsih, Eka Novia; Rahmawati, Ayu Sintya Citra; Martha, Rahma Diyan
JURNAL BIOSHELL Vol 14 No 2 (2025): Oktober
Publisher : Universitas Islam Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56013/bio.v14i2.4572

Abstract

Demam tifoid adalah penyakit infeksi yang ditimbulkan oleh bakteri Salmonella typhi dan menyebar melalui makanan atau minuman yang terkontaminasi tinja atau urine yang mengandung bakteri tersebut. Penyakit ini termasuk ke dalam kategori penyakit menular (transmissible disease). Gejala utama yang biasa muncul antara lain mual, nyeri pada perut, gangguan buang air besar seperti diare atau sembelit, serta demam tinggi. Penelitian ini bertujuan untuk mengetahui hubungan antara cuci tangan dengan kejadian demam tifoid. Penelitian dilakukan dengan desain pendekatan cross-sectional dan melibatkan 30 responden. Berdasarkan hasil analisis menggunakan uji chi-square, diperoleh nilai p = 0,004, yang menunjukkan adanya hubungan yang signifikan antara kebersihan diri dan kejadian demam tifoid, serta faktor lingkungan. Kesimpulan: Terdapat hubungan yang signifikan antara kebersihan diri dengan kejadian demam tifoid. Sebagian besar partisipan dalam penelitian ini adalah perempuan, dengan rentang usia terbanyak berada antara 5 hingga 13 tahun.
Antibacterial Activity of Red Ginger (Zingiber officinale) Extract Against Diarrhea Causing Bacteria Using the Well Diffusion Method Fuzianingsih, Eka Noviya; Rahmawati, Ayu Sintya Citra; Safitri, Yunita Diyah
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10911

Abstract

Acute diarrhea resulting from bacterial infections remains a significant concern in public health. The improper or excessive use of antibiotics contributes to the emergence of antibiotic resistance, creating a need for safer therapeutic alternatives derived from natural sources, such as red ginger (Zingiber officinale). This study aimed to evaluate the antibacterial potential of red ginger extract against Escherichia coli, one of the common bacterial agents causing diarrheal disease. The assessment was carried out using the well-diffusion technique by observing and measuring the diameter of the inhibition zones produced by the extract. The extract was tested at concentrations of 40%, 60%, and 80%, accompanied by a positive control (ciprofloxacin 1 mg/mL) and a negative control (distilled water). The findings demonstrated that the positive control produced a mean inhibition zone of 44.375 mm, whereas the negative control showed no inhibitory activity. The 40% extract yielded an average inhibition zone of 17.125 mm, the 60% concentration produced 19.625 mm, and the 80% concentration generated an average diameter of 22 mm. Statistical evaluation using one-way ANOVA indicated a significance level of ≤ 0.05, and the Duncan post hoc analysis confirmed significant differences between all extract concentrations compared to the antibiotic control. Overall, the study demonstrated that red ginger extract possesses substantial antibacterial activity and effectively suppresses the growth of diarrhea-causing E. coli through the well-diffusion approach.
Co-Authors Anas Fadli Wijaya Fuzianingsih, Eka Novia Fuzianingsih, Eka Noviya Nurjanah, Mutia Hariani Rahma Diyan Martha Safitri, Yunita Diyah