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All Journal Multicore International Journal of Multidisciplinary (MIJM) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM)
Salmasfattah, Novynanda
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Economics, Econometrics & Finance Education Engineering Health Professions Languange, Linguistic, Communication & Media Social Sciences Other

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Training on Oral Drug Administration in Test Animals as an Effort to Strengthen Pharmacology Practicum Competence Prasetyawan, Fendy; Saristiana, Yuneka; Salmasfattah, Novynanda; Alshol, Mohammad Firdaus
Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) Vol. 1 No. 1 (2025): Maret
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/mjpmm.v1.i1.4

Abstract

Training in the skill of administering oral medication to test animals is a form of community service aimed at enhancing pharmacy students' competencies in pharmacology laboratory practices. This activity will take place on May 19, 2025, in the Pharmacology Laboratory at Kadiri University. It will consist of direct training that includes theoretical presentations, demonstrations, and independent practice by students, accompanied by guidance from instructors and laboratory staff. The materials presented include the anatomy of the mouse digestive system, the basic principles of oral gavage, the ethics of using test animals, and safety aspects. The evaluation results indicate that this training has enhanced the participants' understanding of oral gavage techniques as well as their skills in performing the procedure safely and accurately. Based on the comparison of pretest and posttest scores, as well as practical observations, there is a significant improvement in the technical skills and ethical attitudes of the students. This training also enhances the understanding of the importance of animal welfare in pharmacological experiments. This activity is expected to serve as a sustainable model for enhancing the quality of practical learning in the field of pharmacy education.
Prediction of Scabertopin from Tapak Liman (Elephantopus scaber) for Antileukemic Saristiana, Yuneka; Prasetyawan, Fendy; Salmasfattah, Novynanda; Ilmi, Tsamrotul; Fadel, Muhammad Nurul; Besan, Emma Jayanti
Multicore International Journal of Multidisciplinary (MIJM) Vol. 1 No. 1 (2025): May
Publisher : Marasofi International Media and Publishing (MIMP)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64123/mijm.v1.i1.5

Abstract

Leukemia remains a significant global health challenge, necessitating the exploration of novel therapeutic agents with improved efficacy and safety profiles. Elephantopus scaber (commonly known as Tapak Liman) is a medicinal plant traditionally used for various ailments, including cancer. Scabertopin, a sesquiterpene lactone isolated from E. scaber, has attracted scientific interest due to its potential antileukemic properties. This study aims to predict the antileukemic activity of Scabertopin through an in silico approach. The compound's chemical structure was retrieved in SMILES format from the PubChem database and analyzed using the PASS (Prediction of Activity Spectra for Substances) online tool. The prediction results indicated a high probability of antileukemic activity, with a Pa (probability of activity) value of 0.822 and a Pi (probability of inactivity) value of 0.004. These findings suggest a strong likelihood that Scabertopin exhibits antileukemic effects, supporting its potential as a candidate for further pharmacological and clinical investigations. The use of computational prediction tools provides an efficient and cost-effective preliminary screening method for identifying promising bioactive compounds from natural sources. This study contributes valuable insights into the therapeutic potential of Scabertopin and highlights the importance of traditional medicinal plants in drug discovery for leukemia treatment.
Co-Authors Alshol, Mohammad Firdaus Besan, Emma Jayanti Fendy Prasetyawan Muhammad Nurul Fadel Tsamrotul Ilmi Yuneka Saristiana