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All Journal Diponegoro International Medical Journal (DIMJ) GEMBIRA (Pengabdian Kepada Masyarakat)
Choirunnisa, Armadina Fitra
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KELITA (KELAS IBU BALITA) SEBAGAI STRATEGI EDUKASI BERBASIS KOMUNITAS UNTUK PENCEGAHAN STUNTING DI KELURAHAN PANGGUNG LOR, KOTA SEMARANG Maharani, Aidza Aijrina; Alifa, Ailsa Ocha; Putri, Anmitha Rakeesha; Choirunnisa, Armadina Fitra; Kusumaningrum, Devi; Amirudin, Fariha Akmalina; Daharu, Nyes Biru; Nuraida, Siti; Herryananda, Tanasya Fyrsta; Putra, Hega Bintang Pratama; Rachma, Yasmin Aulia
Jurnal Gembira: Pengabdian Kepada Masyarakat Vol 3 No 05 (2025): OKTOBER 2025
Publisher : Media Inovasi Pendidikan dan Publikasi

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Abstract

Stunting merupakan masalah gizi kronis pada balita yang berdampak pada pertumbuhan fisik, perkembangan kognitif, dan produktivitas masa depan. Di Kelurahan Panggung Lor, Semarang Utara, meskipun jumlah kasus relatif lebih rendah, proporsi balita stunting masih tinggi. Untuk mendukung percepatan penurunan stunting, mahasiswa Universitas Diponegoro melaksanakan program KELITA (Kelas Ibu Balita) yang berfokus pada edukasi gizi, pola asuh, serta perilaku hidup bersih dan sehat (PHBS). Program ini melibatkan 16 ibu balita melalui pemeriksaan kesehatan, penyampaian materi interaktif, diskusi, dan kuis edukatif. Hasil evaluasi menunjukkan peningkatan skor pengetahuan rata-rata dari 41 menjadi 88. Kolaborasi lintas sektor menjadi kunci keberhasilan, meski terdapat tantangan seperti keterbatasan waktu peserta dan rendahnya pengetahuan awal. KELITA terbukti efektif meningkatkan pengetahuan ibu dan berpotensi direplikasi di wilayah lain untuk mendukung target nasional penurunan stunting.
THE EFFECT OF DAYAK ONION (ELEUTHERINE PALMIFOLIA) EXTRACT CREAM APPLICATION ON SERUM INTERLEUKIN-6 LEVELS: AN EXPERIMENTAL STUDY IN UVB-INDUCED MALE WISTAR RATS Choirunnisa, Armadina Fitra; Afriliana, Liza; Damayanti, Galih Sari; Widyawati, Widyawati
Diponegoro International Medical Journal Vol 6, No 2 (2025): December 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v6i2.29701

Abstract

Background: Indonesia receives intense ultraviolet B (UVB) exposure. Prolonged exposure to (UVB) radiation is a major environmental factor contributing to oxidative stress and skin inflammation through the overproduction of reactive oxygen species (ROS) and subsequent upregulation of pro-inflammatory cytokines, including interleukin-6 (IL-6). Eleutherine palmifolia, traditionally used in Indonesian herbal medicine, contains abundant flavonoids and phenolic compounds with documented antioxidant and photoprotective properties. Its ability to absorb UV rays and neutralizing ROS suggests potential efficacy as a topical agent for mitigating UVB-induced inflammatory responses. Objective: This study aimed to evaluated the effect of Eleutherine palmifolia extract cream at various concentrations (10%, 15%, 20%) on serum IL-6 levels in UVB-induced male Wistar rats. Methods: A true experimental design with post-test only control group was conducted using 36 male Wistar rats randomly assigned to four groups: control (placebo), P1 (10%), P2 (15%), and P3 (20%). The cream was applied 20 minutes before UVB exposure and again 4 hours after irridation, three times per week for 30 days. Serum IL-6 levels were measured using ELISA. Statistical analysis was performed using Shapiro–Wilk, Levene’s test, one-way ANOVA, and LSD post-hoc test. Results: Mean IL-6 levels (pg/mL): control 1.63; P1 1.59; P2 1.65; P3 1.57. ANOVA indicated a significant differences among groups (p = 0.047). Post-hoc analysis showing a significant difference only between P2 and P3 groups (p = 0.012). Conclusion: The 20% Eleutherine palmifolia cream showed the strongest anti-inflammatory effect, significantly lowering IL-6 compared with 15%, while other group differences were not significant.
Co-Authors Afriliana, Liza Alifa, Ailsa Ocha Amirudin, Fariha Akmalina Daharu, Nyes Biru Damayanti, Galih Sari Herryananda, Tanasya Fyrsta Kusumaningrum, Devi Maharani, Aidza Aijrina Nuraida, Siti Putra, Hega Bintang Pratama Putri, Anmitha Rakeesha Rachma, Yasmin Aulia Widyawati Widyawati