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Pada Vinski, Deby Susanti Pada Vinski
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Computer Science & IT Economics, Econometrics & Finance Engineering Health Professions Law, Crime, Criminology & Criminal Justice Social Sciences

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Stem Cell Therapy for Chronic Fatigue Syndrome: A Promising Approach Pada Vinski, Deby Susanti Pada Vinski; Trofimova, Svetlana; Quintosa, Jaime Rodriguez; Nugroho, Andi Kurniawan; Schroeter, CA; Jovanovic, Stevan
Journal of World Science Vol. 3 No. 11 (2024): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v3i11.1231

Abstract

Chronic Fatigue Syndrome (CFS), or Myalgic Encephalomyelitis (ME), is a debilitating condition marked by persistent fatigue, cognitive dysfunction, and chronic pain, severely affecting quality of life. This study explores the potential of mesenchymal stem cell (MSC) therapy as an innovative treatment for CFS. Using a qualitative descriptive design and case studies, data were gathered through interviews, medical record reviews, and observations of patients undergoing MSC therapy. The findings revealed significant improvements in fatigue, cognitive function, and physical well-being, with participants reporting better memory, concentration, reduced pain, and improved daily functioning. While some sleep disturbances persisted, their severity was reduced. These results highlight the potential of MSC therapy to alleviate CFS symptoms and enhance quality of life. Despite its promise, challenges such as high costs, regulatory hurdles, and the need for standardized protocols persist. Further research is required to confirm long-term efficacy and safety, contributing to the growing evidence for regenerative medicine in treating chronic conditions like CFS.
Exploring the Role of Stem Cell Therapy in Improving Cognitive and Physical Outcomes for Down Syndrome Patients Pada Vinski, Deby Susanti Pada Vinski; Nugroho, Andi Kurniawan; Vinski, Natasha Cinta; Dollar, Dollar; Gunawan, Dahlan
Journal of World Science Vol. 4 No. 1 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i1.1293

Abstract

This review explores the benefits of Mesenchymal Stem Cell (MSC) therapy concerning Down syndrome (DS), cognitive and behavioral disorders, and other related physiological complications. Two pediatric patients with DS participated in this study, receiving MSC therapy over six months through a qualitative case study approach. Patient A was a 5-year-old male experiencing moderate developmental delays and recurrent infections. Patient B was a 6-year-old female facing mild intellectual disabilities and difficulties in social interaction. The initial and follow-up assessments conducted at baseline, three months, and six months after treatment revealed that patients A and B significantly improved in linguistic abilities, attention, social interactions, and motor coordination. Moreover, enhancing inflammatory indices, such as CRP and IL-6, indicated effective regulation of the immune response and reduced inflammation. Both patients adhered to the therapy without any reported side effects. Thus, the findings highlight the potential neuroprotective and immunomodulatory effects of MSC therapy, suggesting it may serve as a viable adjunct treatment for DS. However, due to the limited number of participants and the relatively short observation period, some limitations, such as the small group size and brief study duration, should be acknowledged, necessitating further larger-scale trials to validate these results and establish protocols. This study adds to the existing literature on MSCs in neurodevelopmental disorders and aims to provide a foundation for exploring new treatment options for DS.
Co-Authors Andi Kurniawan Nugroho Dollar, Dollar Gunawan, Dahlan Jovanovic, Stevan Quintosa, Jaime Rodriguez Schroeter, CA Trofimova, Svetlana Vinski, Natasha Cinta