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All Journal Jurnal Kedokteran Meditek Asian Journal of Social and Humanities
Andrean, Melvin
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Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Earth & Planetary Sciences Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health

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Severe Leptospirosis (Weil’s Disease) Complicated by Septic Shock: A Case Report Andrean, Melvin; Sasongko, Calvin; Nabil Mubtadi Falah
Jurnal Kedokteran Meditek Vol 31 No 5 (2025): SEPTEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v31i5.3908

Abstract

Introduction: Weil’s disease is the severe manifestation of leptospirosis, characterized by multiorgan dysfunction and high mortality risk without timely diagnosis and treatment. Early clinical suspicion and prompt intervention are critical for favorable outcomes. Case Illustration: a 51-year-old male with fever, left leg myalgia, jaundice, hypotension, and tachycardia consistent with septic shock. Laboratory evaluation revealed leukocytosis, acute liver injury, and severe acute kidney injury. Additionally, chest imaging revealed bilateral pulmonary infiltrates. Initial management included fluid resuscitation, vasopressors, and broad-spectrum antibiotics. Leptospira IgM serology confirmed the presence of leptospirosis on day 2. Despite severe acute kidney injury, renal function improved without dialysis, and vasopressors were discontinued by day 3. The patient was discharged on day 11, having made a full recovery. Discussion: Severe leptospirosis can present with nonspecific symptoms and progress to septic shock and multiorgan dysfunction. In this case, the diagnosis was supported by IgM-ELISA and a history of exposure to floodwater. Early treatment with broad-spectrum antibiotics and supportive care led to a full recovery. Conclusion: This case highlights the uncommon presentation of septic shock as the dominant feature of Weil’s disease, together with rapid renal recovery without dialysis, underscoring the reversibility of multiorgan dysfunction when promptly managed.
Rare Malaria Case in Jakarta: Diagnostic Challenges and Treatment Strategies for General Practitioners in Non-Endemic Area Andrean, Melvin; Faizi Assafah, Afif
Asian Journal of Social and Humanities Vol. 3 No. 6 (2025): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v3i6.539

Abstract

Malaria, a significant global health issue caused by Plasmodium species, is rare in urban areas like Jakarta but remains endemic in regions such as Papua, Indonesia. This case report highlights a mixed Plasmodium infection (P. vivax and P. malariae) in a 27-year-old male presenting with fever, chills, and body aches. Initially misdiagnosed with dengue fever due to overlapping symptoms, further history revealed recent travel to Papua, leading to malaria diagnosis via blood smear examination. The case emphasizes diagnostic challenges in non-endemic regions where general practitioners may lack familiarity with malaria, especially in atypical presentations. Rapid diagnostic tests, hematological markers, and detailed travel histories are critical for improving diagnostic accuracy. Treatment with dihydroartemisinin-piperaquine and primaquine was effective, showcasing the importance of adhering to national malaria guidelines. This report highlights the need for heightened awareness, better training, and improved diagnostic resources to manage malaria in non-endemic urban areas effectively.
Co-Authors Faizi Assafah, Afif Nabil Mubtadi Falah Sasongko, Calvin