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All Journal Syntax Literate: Jurnal Ilmiah Indonesia Medicinus : Jurnal Kedokteran
Adrya, Jessica
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Humanities Education Environmental Science Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Determinant Factors of Type 2 Diabetes Mellitus Among Older Adults in Kelating Village Pake, Indry Agatha Rihi; Putra, I Made Gede Dwipayana; Adrya, Jessica; Jayaningrat, Dewa Ayu Tri; Wirawan, I Made Suma
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i2.57738

Abstract

Type 2 diabetes mellitus (DM) increased in the elderly population due to metabolic changes and decreased function of pancreatic β cells. This study aims to determine the prevalence of type 2 diabetes mellitus in the elderly and examine the risk factors—such as age, gender, blood pressure, and uric acid levels—that influence the incidence of type 2 DM. This cross-sectional study involved 31 elderly people (≥60 years) in Segara Santhi, Kelating Village, Tabanan, who were selected using purposive random sampling. Fasting blood glucose and uric acid levels were checked using Accu-Chek after fasting for at least 8 hours. Data analysis used the Fisher's Exact Test with a significance of p<0.05. The results show prevalence of type 2 DM was 64.5% (20 of 31 respondents). Age and type 2 DM had no significant association (p= 0.262). However, there was a significant association between type 2 DM and gender (p = 0.012) and uric acid levels (p = 0.029), but not with blood pressure (p = 1,000). The prevalence of type 2 DM in the elderly in Segara Santhi is quite high, but age is not the main factor. Other factors such as diet, physical activity, and genetic predisposition may play a greater role. Further studies with larger sample sizes and multivariate analysis are needed to understand the risk factors for type 2 DM in the elderly more specifically.
Investigating the Prognostic Value of Serum Albumin Levels in Patients Undergoing Hemodialysis: A Systematic Review and Meta-analysis Adrya, Jessica; Sasongko, Calvin; Andrean, Melvin; Kartadinata, Muhammad Faishal; Theis, Aveline Maisie; Putri, Syafira Ayudiah Syah; Mukti, A. Muh. Yasser; Moelyadi, Felly; Varsha, Srigita; Dhika, Veriantara Satya
Medicinus Vol. 15 No. 1 (2025): October
Publisher : Fakultas Kedokteran Universitas Pelita Harapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19166/med.v15i1.10770

Abstract

Background: Hypoalbuminemia, characterized by low serum albumin levels, is frequently observed in patients undergoing hemodialysis and has been identified as a potential predictor of increased mortality risk. This systematic review aims to evaluate the relationship between hypoalbuminemia and mortality in hemodialysis patients, assessing the prognostic value of serum albumin levels as an indicator for patient outcomes. Methods: A comprehensive search was conducted in databases including PubMed, Europe PMC, and Scopus to identify relevant studies. Studies were included if they investigated the association between serum albumin levels and mortality outcomes in adult patients undergoing hemodialysis. Data extraction was performed independently by two reviewers, focusing on study characteristics, patient demographics, albumin levels, and mortality outcomes. Quality assessment of studies was conducted using the Newcastle-Ottawa Scale (NOS). Result: A total of eight studies, encompassing 45,178 hemodialysis patients with a mean age in the 50s, met the inclusion criteria. The studies had a combined male cohort of 22,501 individuals. The definition of hypoalbuminemia varied across studies, with cutoff values ranging from 3.0 to 3.9 g/dL. Follow-up durations spanned from as early as 3 months to a maximum of 6.1 years. The meta-analysis revealed a pooled hazard ratio (HR) of 1.08 (95% CI: 0.94–1.25), suggesting a non-significant association between hypoalbuminemia and increased mortality risk (P = 0.28). However, substantial heterogeneity was present (I² = 79%), indicating variability across studies. Conclusions: Hypoalbuminemia showed a non-significant association with mortality in hemodialysis patients, though variability across studies suggests further research is needed for clarity.
Co-Authors Andrean, Melvin Dhika, Veriantara Satya Jayaningrat, Dewa Ayu Tri Kartadinata, Muhammad Faishal Moelyadi, Felly Mukti, A. Muh. Yasser Pake, Indry Agatha Rihi Putra, I Made Gede Dwipayana Putri, Syafira Ayudiah Syah Sasongko, Calvin Theis, Aveline Maisie Varsha, Srigita Wirawan, I Made Suma